Senior Scientist - Peptide & Protein Display

U175 (FCRS = US175) Novartis Institutes for BioMedical Research, Inc.; San Diego (CA); On-site; USD 94,000 - 174,000; Full time

Benefits offered by this job

Health, life & disability benefits

401(k) with company match

Generous time off

Job summary

Novartis Institutes for BioMedical Research, Inc. in San Diego seeks a Senior Scientist I/II for Exploratory Chemical Biology to advance discovery of small molecules, peptides, and proteins using display technologies and molecular engineering.

You will design and execute discovery campaigns, generate libraries, and collaborate across teams in a fast-paced research environment, contributing to next-generation platforms and breakthrough medicines.

Qualifications

• BS, MS, or recent PhD (within last 2 years) in Molecular Biology, Biochemistry, Biotechnology, Chemical Biology, Bioengineering, or a related field, with 4+ years of relevant experience or training.
• Hands-on experience with display technologies (phage, yeast, and/or mRNA), screening and assay technologies, and molecular biology methods, including library construction and quality control, PCR, cloning, electroporation, and DNA assembly.
• Strong laboratory skills, attention to experimental detail, and accurate, timely documentation in electronic laboratory notebooks.
• Strong organizational and prioritization skills, with the ability to manage multiple tasks and deliver results within established timelines.
• Excellent written and verbal communication and interpersonal skills, with a demonstrated ability to work effectively in a diverse, collaborative team.

Responsibilities

• Design and execute peptide and protein discovery campaigns using phage, mRNA, yeast, and other display or selection platforms.
• Generate, characterize, and quality-control combinatorial libraries using cloning, PCR, DNA assembly, mutagenesis, and sequencing.
• Identify and optimize discovery candidates through iterative selection, molecular engineering, and biochemical or biophysical characterization using ELISA, flow cytometry, BLI, SPR, and related technologies.
• Analyze data and clearly communicate findings to project teams.
• Implement new technologies, workflows, and automation approaches to improve discovery efficiency.

Skills

Display technologies

Phage display

Yeast display

mRNA display

Molecular biology

PCR

Cloning

DNA assembly

Electroporation

Quality control

Library construction

Education

BS/MS/PhD in Molecular Biology, Biochemistry, Biotechnology, Chemical Biology, Bioengineering or related field

Job description

Novartis Institutes for BioMedical Research, Inc. in San Diego seeks a Senior Scientist I/II for Exploratory Chemical Biology to advance discovery of small molecules, peptides, and proteins using display technologies and molecular engineering.

You will design and execute discovery campaigns, generate libraries, and collaborate across teams in a fast-paced research environment, contributing to next-generation platforms and breakthrough medicines.