Senior Scientist, Oral Formulation Sciences (On-site)

Merck & Co.; Rahway (NJ); On-site; USD 117,000 - 184,000; Full time

Benefits offered by this job

Medical insurance

Dental insurance

Vision insurance

401(k)

Paid holidays

Vacation

Sick days

Job summary

Merck & Co., Inc. in Rahway, NJ is seeking a scientist to support formulation development of new chemical entities from first-in-human formulations through final market formulation and manufacturing process robustness.

The role emphasizes collaboration, DOE design, evaluation of new technologies, and development of processes for clinical supplies, with opportunities for patents and publications.

Qualifications

• Ph.D. (or expected by March 2027) in a relevant engineering/science field or MS/BS with 5+ years of industrial experience.

Responsibilities

• Propose innovative approaches for product development, design experiments, execute plans, and interpret data.
• Coordinate development with process chemistry, preformulation, analytical, and characterization groups.
• Outsource formulation development or clinical manufacturing to CDMOs when needed.
• Prepare technical reports and presentations documenting results and progress.
• Contribute to patents, publications, and professional activities to advance science and technology.

Skills

Chemical Engineering

Chemistry

Cross-Functional Teamwork

Data Analysis

Design of Experiments

Innovative Thinking

Manufacturing Processes

Materials Science

Pharmaceutical Sciences

Preformulation

Process Development

Process Optimization

Product Development

Product Formulation

Technology Development

Education

Ph.D. in Chemical Engineering, Biomedical Engineering, Pharmaceutical Sciences or related discipline

Job description

Job Description

Our company's Pharmaceutical Sciences and Clinical Supply organization translates molecules to medicines, working from the discovery interface through registration stability manufacturing by designing, developing and scaling-up the formulation, device, and manufacturing process. Driving drug product design from the bench top to the Good Manufacturing Practice (GMP) manufacturing facilities, our Scientists use cutting edge science to transform drug delivery and manufacturing technology to positively impact patients.

The successful candidate will be a passionate Scientist with strong academic fundamentals and a drive to develop new medicines to improve human health. In this role, the individual will be responsible for supporting the formulation development of new chemical entities as part of a matrix team from initial first in human formulations (suspensions, solutions, capsules, tablets) through final market formulation definition and manufacturing process robustness assessment.

Primary Responsibilities

• Propose new, innovative approaches for product development, generate experimental designs, execute experimental plans, and interpret data. -
• Support internal capability development by evaluating new technologies and deploying them to pipeline assets. -
• Collaborate effectively within and across functional areas and possess advanced knowledge or experience in a specialized scientific area. The desired individual is someone who will bring knowledge and creativity to the position as well as have the discipline to drive results. -
• Execute formulation and process development activities using Design of Experiments for new chemical entities or life cycle management opportunities. -
• Coordinate development activities with process chemistry, preformulation, analytical, and physical characterization groups. -
• Outsource/coordinate formulation development or clinical manufacturing at Contract Development or Manufacturing Organizations. -
• Facilitate manufacturing, packaging, and release of clinical supplies for clinical studies, assist in scale up activities at pilot and commercial scale, and summarize results in technical reports and presentations. -
• Enhance our professional image and competitive advantage through patents, presentations, publications, and professional activities and advance areas such as science and technology development, technical and business strategic improvements, business process innovations. -
• Maintain awareness of relevant new and current technologies, capabilities, and effectively share this knowledge with others. -

Education Minimum Requirements

• Ph.D. in Chemical Engineering, Biomedical Engineering, Pharmaceutical Sciences or related discipline (with expected graduation no later than March 2027). Bachelor of Science (B.S.) or Master of Science (M.S.) degree in Engineering, Pharmaceutical Sciences or related discipline with minimum of 5 years' relevant industrial experience. -

Required Experience and Skills

• Proven ability to identify and develop innovative ideas. -
• Demonstrated ability to independently design and execute complex experiments and data analysis. -
• Ability to work effectively with team members of different skill sets and backgrounds. -
• Strong verbal and written communication skills. -

Preferred Experience and Skills

• Pharmaceutical development experience. -
• Demonstrated ability to identify, fundamentally characterize, and address manufacturing challenges through the development and optimization of novel production technologies. -
• Experience with advanced drug product manufacturing technologies, including: continuous manufacturing, three dimensional (3D) printing, controlled release, and/or oral delivery of large molecules. -
• Experience with process modeling, simulation, and automation integration in the pharmaceutical and/or industrial manufacturing sector. -
• Desire to build new capabilities through the evaluation of new technologies and hands-on optimization of existing technologies. -
• Demonstrated ability to apply the principles of physical/organic chemistry, physical pharmacy, and materials science to solving practical pharmaceutical development problems. -
• Hands-on experience in pharmaceutical pilot plants. -

We offer a comprehensive package of benefits.- Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days.

The salary range for this role is $117,000.00 - $184,200.00

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we "follow the science" and that great medicines can make a significant impact to our world. And we believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.

We are driven by our purpose to develop and deliver innovative products that save and improve lives. With 69,000 employees operating in more than 140 countries, we offer state of the art laboratories, plants and offices that are designed to Inspire our employees as we learn, develop and grow in our careers. We are proud of our 125 years of service to humanity and continue to be one of the world's biggest investors in Research & Development.

Required Skills

Chemical Engineering, Chemistry, Cross-Functional Teamwork, Data Analysis, Design of Experiments (DOE), Innovative Thinking, Manufacturing Processes, Materials Science, Pharmaceutical Sciences, Preformulation, Process Development (PD), Process Optimization, Product Development, Product Formulation, Technology Development

Preferred Skills:

San Francisco Residents Only: -We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only: -We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully- Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. -No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.-

Employee Status: Regular

Relocation: Domestic

VISA Sponsorship: Yes

Travel Requirements: 10%

Flexible Work Arrangements: Not Applicable

Shift: Not Indicated

Valid Driving License: No

Hazardous Material(s): n/a

Job Posting End Date: 10/3/2026

Requisition ID: R416270

*A job posting is effective until 11:59:59PM on the day BEFORE -the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.