Senior Scientist, Non-Viral Delivery Attribute Sciences

Bristol-Myers Squibb Co; Cambridge (MA); On-site; USD 142,000 - 172,000; Full time

Job summary

Bristol Myers Squibb seeks a Senior Scientist, Non-Viral Delivery Attribute Sciences to shape the Attribute Sciences capability and define mechanisms driving targeted LNP performance. You will integrate datasets, expand characterization with new tech, and partner across Research and CMC to translate insights into product decisions.

The role requires strong cell biology expertise, experience with cell-based assays and high-throughput strategies, and a passion for mechanistic understanding to

Qualifications

• Bachelor’s Degree with 7+ years of academic and/or industry experience.
• Master’s Degree with 5+ years of academic and/or industry experience.
• Ph.D. or equivalent advanced degree in the Life Sciences with 2+ years of academic and/or industry experience.

Responsibilities

• Contribute to the development of Attribute Sciences by advancing frameworks and characterization capabilities.
• Develop cellular characterization strategies using primary and patient-derived cells.
• Lead attribute characterization supporting formulation changes, comparability assessments, and investigations.
• Develop high-throughput, automated characterization approaches to improve throughput and reproducibility.
• Expand internal/external characterization capabilities for targeted LNP products with emerging tech.
• Collaborate across multidisciplinary Research and CMC functions to inform product development.
• Communicate findings and actionable recommendations to teams and leadership.
• Provide scientific mentorship to junior scientists and contribute to new approaches.

Skills

Cell biology

High-throughput workflows

Scientific communication

Mentorship

Cross-functional collaboration

Education

Ph.D. in Life Sciences

Master’s degree

Bachelor’s degree

Tools

Flow cytometry

Multiparametric analysis

Job description

At Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it. The Cell Therapy Thematic Research Center is one of BMS’s differentiated research platforms delivering innovative therapies to patients. Our mission is to drive leadership in the use of cellular therapies to harness the power of the immune system in treating hematologic malignancies, solid cancers, and autoimmune disease. More specifically, our discovery and translational scientists are focused on developing next-generation, engineered cell-based therapies. The team is committed to discovering and developing transformative therapies that harness the power of the immune system to improve patient outcomes.

Position Summary

We are seeking a highly motivated and scientifically curious Senior Scientist, Non-Viral Delivery Attribute Sciences to help shape a growing Attribute Sciences capability and establish the mechanistic understanding that will drive next-generation targeted LNP development. This role brings together cell biology, delivery science, and advanced characterization to define the product attributes and biological mechanisms that govern targeted LNP performance. You will integrate scientific datasets, expand advanced characterization capabilities through emerging technologies, and partner across Research and CMC to translate mechanistic insights into product development and program decisions. The ideal candidate brings strong expertise in cell biology and functional assay development, scientific curiosity across disciplines, and a passion for turning mechanistic understanding into innovative targeted therapeutics.

Position Responsibilities

• Contribute to the development of the Attribute Sciences function by advancing scientific frameworks and characterization capabilities that underpin non-viral delivery product and platform development.
• Develop biologically relevant cellular characterization strategies, including primary and patient-derived cell systems, to understand how product attributes and biological context influence functional performance.
• Lead attribute characterization supporting formulation and process changes, comparability assessments, and technical investigations, partnering with Analytical Development, Process Sciences, and Product Development to understand impacts on product quality and functional performance.
• Develop and implement high-throughput and automated characterization approaches to improve experimental throughput, reproducibility, and scalability.
• In close partnership with Analytical Development, identify and expand internal and external characterization capabilities for targeted LNP drug products, including emerging technologies and methodologies.
• Collaborate effectively across multidisciplinary Research and CMC functions and represent Attribute Sciences on program and CMC teams, providing scientific expertise to inform product development and program decisions.
• Effectively communicate scientific findings and actionable recommendations to multidisciplinary teams and leadership to influence delivery strategy and program decisions.
• Provide scientific mentorship to junior scientists, and contribute to the development of new experimental approaches and technologies.

Experience = Basic Qualifications:

• Bachelor’s Degree 7+ years of academic and / or industry experience
• Master’s Degree 5+ years of academic and / or industry experience
• Ph.D. or equivalent advanced degree in the Life Sciences 2+ of academic and / or industry experience

Preferred Qualifications:

• PhD in Cell Biology, Molecular Biology, Immunology, Biochemistry, Bioengineering, Pharmaceutical Sciences, or a related discipline with 2+ years of relevant industry experience; or MS with 5+ years; or BS with 7+ years of relevant experience.
• Strong background in cell biology or a related biological discipline, with demonstrated experience developing and applying cell-based assays to characterize biological activity and functional performance; experience with primary cells, multiparametric flow cytometry, or other advanced cellular characterization approaches.
• Experience with complex drug products, biologics, nanoparticle delivery systems, or related therapeutic modalities is desirable.
• Demonstrated experience applying analytical, biophysical, and cellular characterization approaches to support mechanistic product understanding and establish attribute–performance relationships is preferred.
• Experience with high-throughput, automated, or scalable experimental approaches is preferred.
• Demonstrated ability to work effectively in multidisciplinary teams and thrive in a highly collaborative, cross-functional research environment.
• Strong scientific communication skills, with the ability to present complex data and mechanistic insights clearly and compellingly to varied audiences including project teams and senior leadership.

#LI-Onsite

Compensation Overview:

Cambridge - MA - US: $142,220 - $172,340 The starting pay range(s) listed above is for full-time employees (FTE). You may also be eligible for additional discretionary incentive cash and stock opportunities. We determine starting pay thoughtfully – carefully considering the nature of the role, required skills, work location, schedule and the knowledge and experience you bring. Final compensation is guided by pay equity principles and applicable employment laws. Compensation programs are reviewed on an ongoing basis and may be adjusted over time to reflect evolving market factors, and individual, team or Company performance.

Benefits:

Subject to the terms and conditions of the applicable plans then in effect, you may be eligible to participate in our comprehensive benefit plans – including wellbeing support, retirement and financial protection benefits, and insurance offerings (medical, dental, vision, life and disability).

U.S.-based exempt employees are eligible for Flexible Time Off (FTO), which provides paid time off without a set accrual limit, subject to manager approval, along with 11 paid company holidays each year. Non-exempt employees, RayzeBio employees, and employees located in Puerto Rico receive 160 hours of paid vacation annually for new hires (subject to manager approval), 11 paid company holidays, and 3 optional holidays.

Depending on eligibility, employees may also have access to additional time-off benefits, including paid sick leave, up to two paid volunteer days per year, summer hours flexibility, and leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs.

Eligible employees also enjoy an annual Global Shutdown between Christmas Day and New Year's Day.

U.S.-based job seekers can explore full benefit offerings at https://careers.bms.com/benefits

How We Work

Where you work matters – because collaboration, innovation and patient impact happen in many settings. Our roles are structured across four work models: site-essential, site-by-design, field-based and remote-by-design. The model assigned to this role is based on its core responsibilities. Learn more at https://careers.bms.com/ways-of-working.

Supporting People with Disabilities

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [e-mail]. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Candidate Rights

BMS will consider qualified applicants with arrest and conviction records, pursuant to applicable laws in your area. For roles based in Los Angeles County only: If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

Data Protection

We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection. Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations. If this posting is missing required information required by local law or incorrect, contact BMS at [e-mail] the Job Title and Requisition number. Do not send application-related inquiries to this email. To check your application status, please login to your Candidate Home Account.

We’re creating innovative medicines for patients fighting serious diseases. We’re also nurturing our own diverse team with inspiring work and challenging career options. No matter the role, each one of us makes a contribution. And that makes all the difference.