Senior Scientist, Membrane Protein Biochemistry

Amgen; South San Francisco (CA); On-site; USD 100,000 - 140,000; Full time

Benefits offered by this job

Comprehensive employee benefits package

Retirement and Savings Plan

Discretionary annual bonus

Stock-based long-term incentives

Award-winning time-off plans

Flexible work models

Job summary

Amgen is seeking a Senior Scientist specializing in Membrane Protein Biochemistry in South San Francisco. The role involves designing strategies for membrane protein production, analyzing scientific data, and collaborating across scientific teams. Candidates should have a PhD or equivalent, with experience in membrane protein characterization and strong communication skills. Amgen offers a comprehensive benefits package, including retirement plans and stock-based incentives, fostering a collaborative and innovative work environment.

Qualifications

• PhD or PharmD or MD with relevant post-doc experience.
• Minimum of 3 years of laboratory experience with a Master’s degree.
• Strong track record of scientific accomplishments.

Responsibilities

• Devise and implement membrane protein production strategies.
• Analyze and interpret scientific data for diverse audiences.
• Collaborate on methodological planning for projects.
• Advise on membrane protein technology and mentor junior staff.

Skills

Membrane protein production strategies

Analytical data interpretation

Collaboration skills

Mentoring

Communication skills

Education

Doctorate degree (PhD)

Master’s degree with 3 years experience

Bachelor’s degree with 5 years experience

Tools

ÄKTA systems

HPLC/UPLC

Mass spectrometry

Job description

Senior Scientist, Membrane Protein Biochemistry

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas—Oncology, Inflammation, General Medicine, and Rare Disease— we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions.

As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller, happier lives.

Our award‑winning culture is collaborative, innovative, and science‑based. If you have a passion for challenges and opportunities that lie within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

What You Will Do

In this vital role you will be part of an innovative integrative Protein Generation group within Discovery Protein Science, with responsibilities including the design of strategies for recombinant production of polytopic membrane protein (MP) targets and their purification with detailed analytical characterization. This role will also include opportunities to develop MP platforms and capabilities that increase the success rates of large‑molecule and small‑molecule therapeutic discovery programs.

Key Responsibilities

• Independently devise and implement state‑of‑the‑art membrane protein production strategies through conducting laboratory experiments with rigorous documentation and emphasis on quality of deliverables.
• Analyze and interpret scientific data with the intent to communicate results to audiences with diverse scientific backgrounds.
• Collaborate with other scientists to plan methodological approaches, necessary resources, timelines, and milestones to drive defined projects forward.
• Keep current in membrane protein expertise, advise supervisors and colleagues to shape future membrane protein technology development strategies, and mentor junior scientists and technical staff.

What We Expect Of You

Basic Qualifications

• Doctorate degree PhD
• PharmD
• MD (and relevant post‑doc experience)
• Master’s degree and 3 years of relevant laboratory experience
• Bachelor’s degree and 5 years of relevant laboratory experience

Preferred Qualifications

• Ph.D. plus relevant postdoctoral experience
• Flexible problem‑solving skills, as exemplified by a consistent track record of scientific accomplishments (e.g., peer‑reviewed publications and/or patents)
• Proven expertise with ÄKTA systems and analytical methods for membrane protein characterization using quality‑focused analytical methods such as HPLC/UPLC (SEC, fSEC), spectroscopy, or mass spectrometry.
• Proven expertise in structural biology or dissection of MP molecular pharmacology is a plus.
• Excellent communication skills (both written and oral), leadership skills, and the ability to work well in teams in a fast‑paced environment.

Benefits

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
• A discretionary annual bonus program, or for field sales representatives, a sales‑based incentive plan.
• Stock‑based long‑term incentives.
• Award‑winning time‑off plans.
• Flexible work models where possible.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

Amgen is an Equal Opportunity Employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Sponsorship for this role is not guaranteed.