Senior Scientist I - Process Chemistry

AbbVie Inc.; Chicago (IL); On-site; USD 120,000 - 180,000; Full time

Job summary

AbbVie Inc. in Chicago, IL, is seeking a Senior Scientist to lead chemical process development from pre-clinical to early clinical stages.

You will design and execute scalable synthetic routes for small molecules, peptides, and bioconjugates, with emphasis on quality, safety, and IP generation. The role requires deep expertise in modern synthetic organic chemistry, strong communication, and the ability to work autonomously in a collaborative team.

Qualifications

• BS/MS/PhD in Organic Chemistry with 10+/8+/0+ years experience
• Strong theoretical and practical understanding in organic chemistry
• Broad expertise in modern synthetic organic chemistry, purification, spectral interpretation; peptides/bioconjugations/biocatalysis/AI/ML/oligonucleotides desired
• Ability to search the literature and evaluate solutions to synthetic problems

Responsibilities

• Develop and execute chemical processes to support clinical development
• Demonstrate scientific initiative to resolve project hurdles
• Learn quickly and adapt course when needed
• Build cross-functional relationships to enable high performance
• Work autonomously in lab research and method development
• Maintain high productivity in the laboratory
• Publish research and present at conferences
• Foster a learning environment and embrace ideas
• Adhere to safety, quality, and conduct standards

Skills

Organic synthesis

Synthetic organic chemistry

Spectral analysis

Peptides

Bioconjugation

Biocatalysis

AI/ML awareness

Oligonucleotides

Education

Bachelor’s degree in Organic Chemistry

Master’s degree in Organic Chemistry

PhD in Organic Chemistry

Job description

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.

Job Description

The Process Chemistry team is responsible for inventing and executing the chemical processes and preparing active pharmaceutical ingredient (API) to enable toxicology studies, clinical trials, and drug product development for AbbVie’s pre-clinical and clinical candidates. We create valuable intellectual property through composition of matter, chemical processes, and technology, resulting in the development of safe and cost-effective commercial manufacturing processes.

AbbVie Process Chemistry is seeking a highly motivated Senior Scientist to conduct chemical process research and development, supporting projects from pre-clinical stages through early clinical phases.

Key Responsibilities:

• The successful candidate will be responsible for developing and executing chemical processes to support clinical development of potential therapies, which may include small molecules, antibody drug conjugates, peptides, and/or oligonucleotides.
• Routinely demonstrate scientific initiative and creativity in research or development activities to resolve key project hurdles.
• Learns fast, grasps the "essence", and can change course quickly where indicated.
• Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance.
• Highly autonomous and productive in performing laboratory research or method development, requiring only minimal direction from or interaction with supervisor.
• Maintain a high level of productivity in the laboratory setting.
• Publish research in peer-reviewed journals and present their work at scientific conferences.
• Creates a learning environment, embraces the ideas of others, open to suggestions and experimentation for improvement.
• Adheres to corporate standards regarding code of conduct, safety, quality, and appropriate

Qualifications

• Bachelor’s, Master’s, or PhD Degree in Organic Chemistry with typically 10+ (BS), 8+ (MS) or 0+ (PhD) years of experience
• Possesses a thorough theoretical and practical understanding of own scientific discipline.
• A broad range of functional expertise in modern synthetic organic chemistry, compound purification, spectral analysis/interpretation. Experience in peptides, bioconjugations, biocatalysis, AI/ML, or oligonucleotides is also desired.
• An ability to search the chemical literature and evaluate potential solutions to synthetic problems.
• Strong written and verbal communication skills.

Additional Information

• The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeofthis posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographiclocation,andwemayultimatelypaymore or less than the posted range. This range may bemodifiedin thefuture.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.
• This job is eligible toparticipatein our short-term incentiveprograms.

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.Theamountandavailabilityof anybonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employeeremainsin the Company'ssoleandabsolutediscretion unless and until paid andmay bemodifiedat the Company’s sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html