Senior Scientist I/II, Process Engineering

BioSpace; North Chicago (IL); On-site; USD 90,000 - 150,000; Full time

Benefits offered by this job

PTO

Medical/Dental/Vision insurance

401(k)

Job summary

AbbVie is seeking a Process Engineer within the CrySP Center of Excellence, part of the Process Engineering function. The role focuses on developing robust, scalable processes for small molecule APIs, ADCs, toxins, CAIs, and drug products, guiding projects from early development through commercialization.

Emphasis on crystallization, separation, and partner collaboration across chemistry, analytics, and regulatory fields.

Qualifications

• BS/MS/PhD in Chemical Engineering or related field.
• 10+ years (BS) / 8+ years (MS) of relevant industrial experience.
• Strong oral and written communication and teamwork skills.

Responsibilities

• Develop robust scale up and manufacturing processes for small and/or large molecule assets through all phases of development.
• Perform laboratory experiments and process modeling to support understanding and optimization.
• Address challenging problems with separations and isolations using thermodynamics, crystallization fundamentals, transport phenomena, and mathematical modeling.
• Author and/or review technical documents summarizing process development efforts.
• Exhibit a collaborative nature and communicate findings to multidisciplinary teams.
• Author publications and present at scientific conferences.

Skills

Chemical engineering

Communication skills

Team player

Experimental techniques

Education

Chemical Engineering degree (BS/MS/PhD)

Job description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onLinkedIn,Facebook,Instagram,XandYouTube.

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onLinkedIn,Facebook,Instagram,XandYouTube.

Job Description

Process Engineering, a part of AbbVie R&Ds Small Molecule CMC Development organization, is responsible for designing and developing scalable processes to make small molecule drug substances and drug products, including antibody drug conjugates (ADCs), throughout pre-clinical and clinical development stages. Process Engineering also partners with Biologics CMC Development and Aesthetics R&D functions to provide active engineering support to enable robust process scale-up and manufacturing of biologics drug substances and drug products, including toxins and cosmetic active ingredients (CAIs). We contribute to the development of innovative engineering technologies and create valuable intellectual property through the composition of matter, chemical processes, and technologies resulting in cost-effective commercial manufacturing processes. We support the development of the supply chain for pipeline molecules and help prepare and defend CMC regulatory content.

Chemical/Bio Engineers support pipeline projects through all phases of development. Early in development, engineers focus on ensuring that the process can be run safely, identifying and addressing scale-up issues, enabling processes that can be scaled-up successfully. In the later stages of development, engineers optimize the drug substance and drug product processes and lead manufacturing campaigns. Engineers also work cross-functionally to transfer the optimized process to manufacturing sites, develop control strategy, and prepare reports to support regulatory filings.

Role Overview

The successful candidate will play a key role in the Center of Excellence in Crystalline Drug Substance and Drug Product (CrySP), a part of Process Engineering function.The core deliverable of Process Engineering is to develop robust processes to manufacture small molecule Active Pharmaceutical Ingredients (API), Antibody Drug Conjugates (ADCs), toxins, cosmetic active ingredients (CAIs), and drug products utilizing strong engineering fundamentals. The idea candidate will have background in crystallization fundamentals and crystallization process development. Process Engineering also leads the development of isolation and purification strategies for both small and large molecule compounds. The ideal candidate will have a passion for hands-on laboratory process development and a proven track record in research and development. The candidate is also expected to lead the identification and development of novel approaches and technologies to enhance process development efficiency and commercialization. The candidate must exhibit a collaborative nature in identifying process challenges on a wide range of projects and participate in a cross-functional teams to deliver against specific project needs.

Key Responsibilities

• Develop robust scale up and manufacturing processes, supporting small and/or large molecule assets through all phases of development.
• Performlaboratory experiments and process modeling to support process understanding and optimization.
• Addresschallenging problems with separations, and/or isolations using expertise in thermodynamics, crystallization fundamentals, transport phenomena, and mathematical modeling.
• Author and/or review technical documents summarizing process development efforts.
• Exhibita collaborative nature in identifying process challenges on a wide range of projects and communicate findings and recommendations effectivelyby multi-disciplinary interactions with organic chemists, analytical chemists, process development engineers, pilot plant engineers, drug product development scientists, program managers, and regulatory affairs specialists.
• Author publications and present at scientific conferences.

Qualifications

• BS, MS, or PhD in Chemical Engineering or a related field and 10+ (BS), 8+ (MS), or 0+ (PhD) years of relevant industrial experience.
• Job level will be commensurate with academic and/or industrial work experience.
• Candidates are expected to have a strong background in chemical engineering and the proven ability to demonstrate their skills in this field.
• The candidate is expected to demonstrate the ability to learn, understand, and master new experimental techniques.
• The candidate is required to possess effective oral and written communication skills and be a strong team player.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

• The compensation range described below is the range of possible base pay compensation that the Companybeliefs in good faith it will pay for this role at the time of this posting based on the job grade for this position.Individual compensation paid within this range will depend on many factors including geographic location,and we may ultimately pay more or less than the posted range. This range may be modified in the future.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.
• This job is eligible toparticipatein our long-term incentiveprograms.

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission,incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employeeremainsin the Company's sole andabsolutediscretion unless anduntil paid andmay bemodifiedat the Companys sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visithttps://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

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https://www.abbvie.com/join-us/reasonable-accommodations.html