Senior Scientist I, Cancer Immunology

Revolution Medicines, Inc.; San Francisco (CA); On-site; USD 149,000 - 186,000; Full time

Job summary

Revolution Medicines in Redwood City, CA, seeks a scientist to advance assets in preclinical and clinical development within the Cancer Immunology team. You will design and execute translational studies, identify emerging technologies, and communicate findings to cross-functional partners.

Required are a PhD in immunology or cancer biology, 4+ years in biotech/pharma, and strong skills in tumor immunology, biomarkers, and in vivo models.

Qualifications

• PhD in immunology, cancer biology or related field with expertise in tumor immunology.
• Proven publication record and research excellence.
• Experience designing in vivo studies and biomarker discovery.

Responsibilities

• Design, develop, validate and execute in vitro, in vivo, and ex vivo studies for translational questions.
• Identify new technologies to enhance biomarker discovery and mechanistic understanding.
• Drive reverse translation by testing hypotheses from clinical findings to inform development plans.
• Stay current with tumor immunology advances and propose new combination strategies.
• Analyze and communicate data effectively across teams and at conferences.
• Represent the company at scientific conferences and external engagements.

Skills

Immunology techniques

In vivo model design

Biomarker discovery

Cross-functional collaboration

Data interpretation

Scientific communication

Oncology drug discovery

Education

PhD in immunology or cancer biology

Tools

Flow cytometry

Molecular biology techniques

In vivo models

Job description

Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide.

Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients.

The Opportunity:

As a key player in our Cancer Immunology team, you will use your immuno-oncology expertise to help advance Revolution Medicines’ assets in preclinical and clinical development.

Responsibilities:

• Design, develop, validate and execute in vitro, in vivo, and ex vivo studies to address key translational questions and support immuno-oncology biomarker plans.
• Identify, evaluate and implement emerging technologies to enhance translational biomarker discovery and mechanistic understanding.
• Drive reverse translation efforts by formulating and testing hypotheses derived from clinical finding as appropriate to inform clinical development plans.
• Stay abreast of advances in tumor immunology and immunotherapy, identifying novel combination strategies and contributing to preclinical evaluation.
• Analyze, interpret, and communicate complex data effectively across internal cross-functional teams and at external scientific meetings.
• Represent Revolution Medicines at scientific conferences and other external engagements.

Required Skills, Experience and Education:

• D. in immunology, cancer biology, or a related discipline, with deep expertise in tumor immunology, immuno-oncology biomarkers, and/or immunotherapy.
• Proven track record of research excellence, evidenced by high-impact publications.
• Expertise in in vivo model design to evaluate the efficacy and mechanisms of action of therapeutic agents and enable biomarker discovery, both internally and via contract research organizations.
• Strong technical expertise in immunology techniques including multi-parameter flow cytometric analyses, primary human cellular/tissue-based functional assays, cell biology and molecular biology to guide/inform mechanism of action and biomarker discovery.
• Strong problem-solving skills and ability to independently oversee scientific projects, rigorously analyze and interpret scientific data while maintaining attention to detail.
• Excellent written and verbal communication skills. Thrives in a fast-paced, collaborative, interdisciplinary team setting.
• 4+ years of relevant biotech or pharmaceutical industry experience in oncology drug discovery and development.

Preferred Skills:

• Hands-on experience with humanized mouse models is desirable.
• Familiarity with multiomics analyses and integrating computational insights into experimental designs.

The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact [e-mail].

Base Pay Salary Range

$149,000 - $186,000 USD