Senior Scientist, I

AbbVie; Worcester (MA); On-site; USD 110,000 - 170,000; Full time

Benefits offered by this job

Paid time off

Health insurance

401(k) plan

Incentive programs

Job summary

AbbVie in Worcester, MA is seeking a highly skilled scientist to conceive and implement novel experimental approaches to answer complex questions. You will develop and optimize purification processes for biologics and contribute to project science across disciplines.

Responsibilities include technology transfer to pilot and cGMP facilities, protein property modeling, and exploring innovative technologies. Strong collaboration and communication are essential for success.

Qualifications

• Bachelor’s degree with extensive experience in biophysics/biotechnology.
• Experience in biophysical characterization and protein structure modeling preferred.
• Strong communication of scientific results to multifunctional teams.

Responsibilities

• Develop recovery and purification process using clarification, chromatography, and membrane filtration for mAbs, bispecifics, and ADC.
• Design and execute process development and characterization activities, impurity and viral clearance studies.
• Technology transfer to pilot lab and cGMP facilities; support campaigns.
• Model protein properties to understand manufacturability impacts.
• Explore innovative technologies (AI, automation, novel resins) across AbbVie areas.
• Capable of publishing and presenting research; may contribute to patents.
• Adhere to safety, GxP, and regulatory standards as applicable.

Skills

Problem-solving

Communication

Cross-functional collaboration

Project coordination

Education

Bachelor’s degree (or equivalent)

Master’s degree (or equivalent)

PhD (no experience required)

Tools

LC-MS

Job description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com.

Job Description

Conceive and implement novel experimental approaches to answer scientific questions. Investigate, identify, develop, and optimize new methods and techniques. Contribute to project science in area of expertise. Develop productive collaborations and communications with other groups across science disciplines.

Responsibilities

• Develop recovery and purification process that utilizes clarification, chromatography, and membrane filtration technologies for monoclonal antibodies, bispecifics and antibody drug conjugates (ADC). Provide deeper understanding of process performance using appropriate experimental and modeling tools.
• Design and execute process development and characterization activities, impurity and viral clearance studies. Highly independent and productive in performing laboratory research and/or development, requiring only minimal direction from or interaction with supervisor.
• Responsible for technology transfer to pilot lab and cGMP manufacturing facilities, troubleshooting and investigation activities. Provide person-in-plant support for pilot and/or cGMP manufacturing campaigns.
• Play a key role in coming up with protein structure properties modeling and/or analytical characterization to build deep scientific understanding of protein property and its impact on manufacturability.
• Exhibit a strong motivation to implement and advance various innovative technologies (such as AI skillset, automation/highthroughput, and/or novel resins) in relevant areas across AbbVie.
• Routinely demonstrate scientific initiative and creativity in research or development activities. Capable of being a primary author of publications, presentations, regulatory documents and/or primary inventor of patents.
• Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials, controlled drug and radioactive compounds, GxP compliance, and animal care where applicable.

Qualifications

• Bachelor’s Degree or equivalent education and typically 10 years of experience, Master’s Degree or equivalent education and typically 8 years of experience, PhD and no experience necessary.
• Possess thorough theoretical and practical understanding of own scientific discipline.
• Education background in chemical engineering, biophysics, biochemistry, biochemical engineering, or biotechnology is preferred.
• Experience in areas of biophysical characterization and/or protein structure modeling is strongly preferred.
• Experience in areas of purification process development is strongly preferred.
• Direct experience and/or collaboration experience in areas of biologics LC-MS is preferred.
• Demonstrate excellent communication skills and specifically illustrate strong oral and written technical communications.
• Seamlessly present research outcomes to multifunctional teams.
• Play a strong team player in a cross functional collaborative environment thriving for world class excellence and maintains strong working relationships with internal, global, and external collaborators.
• Demonstrated problem-solving skills and capability to overcome complex issues.
• Demonstrated success in coordinating and executing important projects to achieve business goals.
• Must have a “results-oriented” work ethic and a positive “can-do” attitude with a strong sense of urgency and self‑motivated desire to achieve.

Benefits

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
• This job is eligible to participate in our short‑term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html