Senior Scientist, Engineering- Cell Banking

Scorpion Therapeutics; Pennsylvania; On-site; USD 117,000 - 184,000; Full time

Benefits offered by this job

Annual bonus

Long-term incentive

Medical/dental/vision

401(k)

Job summary

Scorpion Therapeutics is seeking a senior cell culture scientist to lead mid-to-late stage cell bank programs for biologics. You will drive process development, qualification, and transfer activities across internal teams and CMOs.

The role emphasizes risk assessments, DOE studies, data analysis, and regulatory documentation for licensure and commercialization, with a focus on safety and timely execution. Applicants should have a Bachelor's with 5+ years cell culture experience in pharma, or a

Qualifications

• Bachelor's degree with 5+ years cell culture experience in pharma, or higher degree with relevant experience.
• Hands-on mammalian/microbial cell culture (adherent/suspension) including cryopreservation and cell bank prep.
• Strong communication, problem-solving, and project management skills.

Responsibilities

• Support mid-late stage and commercial cell bank projects for large molecule programs; manage commercialization activities for late-stage pipeline and/or post-market working cell banks for biologics/vaccines.
• Lead cell bank process risk assessments, documentation, process characterization, technology transfer, and qualification of new cell banks (for licensure/commercialization).
• Plan and execute work to support working cell bank commercialization; identify/implement process changes, evaluate investigations/trends, and support regulatory filings.
• Design and execute laboratory experiments; analyze data; communicate results via presentations and technical reports.
• Collaborate with internal teams and CMOs; deliver process documentation packages, review batch records, and provide investigation support.
• Author regulatory/technical documentation for cell bank transfer, long-term storage stability, qualification, and licensure; support regulatory queries/inspections.

Skills

Cell culture development

Cell culture metabolism

Upstream lab execution

Education

Bachelor's +5 years

Master's +3 years

PhD + industry experience

Job description

Responsibilities:

• Support mid-late stage and commercial cell bank projects for large molecule programs; manage commercialization activities for late-stage pipeline and/or post-market working cell banks for biologics/vaccines.
• Lead cell bank process risk assessments, documentation, process characterization, technology transfer, and qualification of new cell banks (for licensure/commercialization).
• Plan and execute work to support working cell bank commercialization; identify/implement process changes (replenishment lots, control strategies), evaluate investigations/trends, and support regulatory filings.
• Design and execute laboratory experiments; analyze data; communicate results via presentations and technical reports.
• Collaborate with internal teams and CMOs; deliver process documentation packages, review batch records, and provide investigation support.
• Author regulatory/technical documentation for cell bank transfer, long-term storage stability, qualification, and licensure; support regulatory queries/inspections.
• Provide technical leadership and drive standardization of best practices across the network; execute assignments on accelerated timelines with safety/compliance focus.

Minimum Required Education/Experience:

• Bachelor's + 5 years cell culture experience in pharma; OR Master's + 3 years; OR Ph.D. with no industry experience.

Required Expertise/Skills:

• Cell line development and cell culture metabolism/death/media adaptation.
• Hands-on mammalian/microbial cell culture (adherent/suspension), including enumeration/expansion, virus infection, cryopreservation, cell bank prep, lab operations.
• Upstream lab execution, DOE, statistical analysis, strong communication and problem-solving, project management.

Preferred Expertise/Skills:

• Large molecule process development; US/EU regulatory and cGMP; authoring regulatory documents; bench lead/team oversight; GMP manufacturing support and batch record reviews.
• QbD, Lean Six Sigma; filings/inspections (IND/MAA/BLA).

Compensation/Benefits (if applicable/explicit):

• Salary range: $117,000.00-$184,200.00; eligible for annual bonus and long-term incentive (if applicable).
• Comprehensive benefits include medical/dental/vision, 401(k), paid holidays/vacation, and sick/compassionate days.