(Senior) Scientist, Computational Neuroscience

Flagship Pioneering; Cambridge (MA); On-site; USD 132,000 - 259,000; Full time

Benefits offered by this job

Healthcare coverage

Annual incentive program

Retirement benefits

Broad range of other benefits

Job summary

Flagship Pioneering seeks a (Senior) Scientist, Computational Neuroscience to build scalable pipelines for biophysical neuron modeling and apply ML to large neural datasets. The role is based in Cambridge, MA with a preference for on-site engagement and welcomes international candidates.

The ideal candidate will have a PhD or MSc in a related field, 2+ years of industry/postdoc experience, strong neural modeling skills, and proficiency in Python with ML frameworks such as PyTorch or TensorFlow.

Qualifications

• MSc/PhD in Computational Neuroscience, Physics, Applied Math, CS, AI/ML or related field.
• 2+ years of full-time industry or postdoctoral experience (5+ years for MSc).
• Strong experience with computational modeling of neural systems.
• Hands‑on ML or time-series analysis experience.

Responsibilities

• Develop end-to-end computational pipelines for biophysical neural modeling.
• Apply ML and statistical inference to neural datasets.
• Collaborate to shape the technical roadmap and prototype methods.

Skills

Neural modeling

Python

ML/Time-series

Industry experience

Team collaboration

Education

MSc/PhD in Computational Neuroscience or related field

Tools

PyTorch

TensorFlow

NumPy/SciPy/Pandas

Job description

The Company

Flagship Labs 119 Inc. (FL119) is an early-stage technology company pioneering a new frontier at the intersection of neuroscience and computation. We are developing next-generation technologies to transform how intelligent systems are built. We believe that the future of artificial intelligence demands a fundamental rethinking of today’s paradigms. Our mission is bold and urgent: to build a future where naturalistic, robust intelligence can emerge and operate sustainably at scale.

The Role

FL119 is seeking a (Senior) Scientist, Computational Neuroscience to join our team. Leveling is flexible based on experience. This role will focus on building scalable computational pipelines for biophysical modeling and applying machine learning techniques to large-scale neural datasets.

The role is based in Cambridge, Massachusetts, with a preference for on-site engagement. International candidates are welcome to apply.

How You Will Contribute

• Own the development of end-to-end computational pipelines for biophysical modeling of neurons and neural populations.
• Implement machine learning and statistical inference methods to construct and analyze bio-realistic networks from neural recordings.
• Actively shape the technical roadmap by proposing, prototyping, and evaluating modeling and inference approaches in close collaboration with the broader team.

The Ideal Candidate Will Have

• MSc or PhD in Computational Neuroscience, Physics, Applied Mathematics, Computer Science, AI/ML, or a related field.
• 2+ years of full-time industry or postdoctoral experience (5+ years for MSc).
• Strong experience with computational modeling of neural systems.
• Hands‑on experience applying machine learning or statistical methods to complex time‑series data.
• Proficiency in Python and scientific computing libraries (e.g., NumPy, SciPy, Pandas), and familiarity with ML frameworks such as PyTorch or TensorFlow.
• Comfort working in high‑ambiguity R&D environments and building novel methods from first principles.
• Passion for working at the intersection of AI and experimental biology.

About Flagship Pioneering

Flagship Pioneering is a bioplatform innovation company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value. Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID‑19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE's "Change the World" list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World's Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

Flagship Pioneering is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

Salary and Benefits

The salary range for this role is $132,000 - $259,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience.

• healthcare coverage
• annual incentive program
• retirement benefits
• a broad range of other benefits

Compensation and benefits information is based on FL119's good faith estimate as of the date of publication and may be modified in the future.

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