Senior Scientist, CMC Modeling & Tech Transfer

Merck & Co.; Boston (MA); Hybrid; USD 210,000 - 331,000; Full time

Benefits offered by this job

Hybrid work arrangement

Comprehensive benefits package

Job summary

Merck & Co. in Rahway, NJ (hybrid) seeks a Distinguished Scientist to lead Brick 1 modeling within CMC Lighthouse Pillar 2: Digitally Enabled Technology Transfer. You will define strategy and execution plans to establish, mature, and deploy models across domains.

Lead cross‑functional teams, govern model lifecycle, and ensure regulatory readiness. The role requires expertise in mechanistic, statistical, hybrid, and AI/ML models, translating findings into action for development, manufacturing,

Qualifications

• Ph.D. in chemical engineering, chemistry, biochemistry, pharmaceutical sciences, systems engineering, applied mathematics, data science, or related field; 15+ years of industry experience preferred.
• Recognized scientific or technical leadership in CMC development, technology transfer, manufacturing sciences, process development, analytical development, or model-informed development.
• Strong ability to define and lead cross-functional technology strategies or portfolios from concept through sustained implementation.
• Broad knowledge of mechanistic, statistical, hybrid, empirical, and AI/ML modeling approaches and their fit-for-purpose application across CMC domains.

Responsibilities

• Serve as the scientific authority for the integrated portfolio of models required to enable digitally supported CMC technology transfer.
• Establish a cross-modality framework for determining required models and where reuse is possible.
• Guide development and application of mechanistic, statistical, hybrid, empirical, and AI/ML models with clear use, assumptions, uncertainty, and validation.

Skills

Analytical Thinking

Bioanalytical Techniques

Biochemistry

Chemistry

CMC Strategy

Data Analysis

Experimentation

Influencing Skills

Manufacturing

Product Development

R&D Strategy

Regulatory CMC

Scientific Leadership

Strategic Foresight

Technology Transfer

Education

Ph.D. in chemical engineering, chemistry, biochemistry, pharmaceutical sciences, systems engineering, applied mathematics, data science, or related field

Job description

Merck & Co. in Rahway, NJ (hybrid) seeks a Distinguished Scientist to lead Brick 1 modeling within CMC Lighthouse Pillar 2: Digitally Enabled Technology Transfer. You will define strategy and execution plans to establish, mature, and deploy models across domains.

Lead cross‑functional teams, govern model lifecycle, and ensure regulatory readiness. The role requires expertise in mechanistic, statistical, hybrid, and AI/ML models, translating findings into action for development, manufacturing,