Senior Scientist, Chemistry (Onsite)

Merck & Co.; Boston (MA); On-site; USD 131,000 - 207,000; Full time

Benefits offered by this job

Medical, dental, vision coverage

401(k) retirement benefits

Paid holidays and vacation

Job summary

Merck & Co. in Boston, MA is seeking an exceptional chemist to join the Discovery Process Chemistry group, contributing to innovative solutions across discovery projects and enabling progression to preclinical development.

The candidate will apply cutting-edge methodologies to design synthetic routes, collaborate across Medicinal and Process Chemistry, and communicate findings effectively to multidisciplinary teams in a fast-paced research environment.

Qualifications

• PhD in Organic Chemistry completed or expected by 2026/2027.
• Must have conducted outstanding research in their field.
• Demonstrated creativity and innovation in problem solving.
• Productivity and efficiency in the lab.
• Strong written and oral communication skills.
• Excellent collaboration skills.
• Established scientific reputation supported by publications and external presentations.

Responsibilities

• Develop innovative solutions to complex chemistry problems across projects in the discovery phase.
• Apply cutting-edge methodologies to synthetic route design to enable medicinal chemistry research and accelerate delivery of target compounds to fund pre-clinical and clinical studies.
• Collaborate with Process and Medicinal Chemistry networks and across Discovery and Preclinical functions.

Skills

Analytical Chemistry

Analytical Method Development

Chemical Proteomics

Chemical Synthesis

Chromatography

Laboratory Automation

Mass Spectrometry Based Proteomics

Medicinal Chemistry

Organic Chemistry

Pharmacodynamics

Pharmacokinetics

Process Analytical Technology

Protein Chromatography

Education

PhD in Organic Chemistry

Job description

Job Description

Our Company is currently seeking an exceptional chemist to join the Discovery Process Chemistry group located at our Boston, MA site. This role offers the opportunity to join a vibrant group of innovative laboratory scientists with broad impacts across our late discovery and early development portfolios.

• Core responsibilities include the development of innovative solutions to complex chemistry problems across a portfolio of projects in the discovery phase, from lead identification through candidate selection. A successful candidate is expected to apply cutting edge methodologies to synthetic route design in order to enable medicinal chemistry research and accelerate the delivery of target compounds to fund pre-clinical and clinical studies. Close collaboration is expected with colleagues across the Process and Medicinal Chemistry networks and throughout the Discovery and Preclinical functions.
• The candidate must be highly self-motivated, possess strong experimental skills, have excellent written and oral communication abilities, collaborate effectively on multidisciplinary teams and across geographies, and be able to demonstrate flexibility in adapting to change in a fast-paced, dynamic research environment.
• In addition, the candidate will be expected to remain current with the latest synthetic methodologies, drive innovation, apply new concepts to continuously improve group capabilities, and be active in the external scientific community via publications and external presentations.

Education Minimum Requirement

• PhD in Organic Chemistry achieved or expected in 2026/2027.

Required Experience and Skills

• Must have conducted outstanding research in their field of expertise that may be shared during the interview process
• Demonstrated creativity and innovation in problem solving
• Productivity and efficiency working in the lab
• Strong written and oral communication skills
• Excellent collaboration skills
• Established scientific reputation supported by publications and external presentations.

Required Skills

Analytical Chemistry, Analytical Method Development, Chemical Proteomics, Chemical Synthesis, Chemistry, Chromatography, Laboratory Automation, Laboratory Operations, Mass Spectrometry Based Proteomics, Medicinal Chemistry, Organic Chemistry, Pharmacodynamics, Pharmacokinetics, Process Analytical Technology (PAT), Protein Chromatography

US and Puerto Rico Residents Only

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics.--As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities.- For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

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We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

The salary range for this role is $131,400.00 - $206,800.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee's position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits.- Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits .

San Francisco Residents Only

We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only

We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance

Employee Status

Regular

Relocation

Domestic

VISA Sponsorship

No

Travel Requirements

10%

Flexible Work Arrangements

Not Applicable

Shift

Not Indicated

Valid Driving License

No

Hazardous Material(s)

n/a

Job Posting End Date

08/24/2026

*A job posting is effective until 11:59:59PM on the day BEFORE -the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Requisition ID

R412576