Senior Scientist, Analytical Development – Small Molecules

Cytokinetics (Ireland) Limited; South San Francisco (CA); On-site; USD 162,000 - 189,000; Full time

Job summary

Cytokinetics in South San Francisco (CA) seeks a Senior Scientist, Analytical Development, to lead analytical studies for our small molecule pipeline. You will design and execute methods, interpret data, and support drug substance and drug product development across early research to clinical stages.

Collaborating with Process Chemistry, Pharmaceutical Development, DMPK, and Manufacturing, you will troubleshoot methods, transfer validations, and prepare reports while maintaining cGMP compliance

Qualifications

• 5+ years in analytical development, quality control, or related labs.
• Hands-on with analytical characterization of small molecule drug substances and products.
• Familiar with cGMP and regulatory practices.
• Strong written documentation and cross‑functional collaboration.

Responsibilities

• Design and document analytical studies for drug substance and product.
• Develop, qualify, troubleshoot analytical methods.
• Perform hands-on chromatographic and spectroscopic testing.
• Characterize substances, intermediates, degradation products.
• Prepare study reports and technical summaries.
• Support method transfers and validation activities.

Skills

Analytical Chemistry

HPLC/UHPLC

LC-MS

GC

Dissolution

cGMP

Technical writing

Cross-functional

Problem solving

Experiment design

Education

BS/MS Analytical Chemistry

PhD preferred

Tools

LC-MS

GC

Dissolution

Karl Fischer

XRPD

DSC/TGA

Particle Size Analysis

Job description

Cytokinetics in South San Francisco (CA) seeks a Senior Scientist, Analytical Development, to lead analytical studies for our small molecule pipeline. You will design and execute methods, interpret data, and support drug substance and drug product development across early research to clinical stages.

Collaborating with Process Chemistry, Pharmaceutical Development, DMPK, and Manufacturing, you will troubleshoot methods, transfer validations, and prepare reports while maintaining cGMP compliance