Senior Scientist - Analytical Commercialization Technology (ACT)

1000 Merck Sharp & Dohme LLC; Rahway (NJ); In loco; USD 117.000 - 184.000; Tempo pieno

Descrizione del lavoro

Merck & Co., Inc. in Rahway, NJ is seeking a Senior Scientist in the Analytical Commercialization Technology group to develop and validate analytical methods, analyze data, and support drug product development and regulatory submissions in a cGMP environment.

The ideal candidate will collaborate across disciplines, apply advanced analytical tools such as UHPLC/HPLC, GC, UV/IR, and dissolution testing, and contribute to tech transfer and process characterization.

Competenze

• PhD in Chemistry or related discipline with no experience required OR MS in Analytical Chemistry with 5+ years of relevant pharmaceutical development experience.
• Strong knowledge and hands-on experience in chemistry and analytical techniques.
• Demonstrated problem-solving ability and cross-functional collaboration.
• Excellent verbal and written communication skills.

Mansioni

• Utilize advanced analytical tools for problem-solving and data analysis.
• Develop and validate robust analytical methods for drug products.
• Conduct drug product testing and analytical investigations in a cGMP environment.
• Characterize drug products and manufacturing processes.
• Prepare CMC documents for global regulatory submissions.
• Support technology transfer for commercial manufacture.

Conoscenze

Analytical Method Development

Mass Spectrometry Based Proteomics

Data-Driven Decision Making

Chemometrics

Chromatography

Process Analytical Technology (PAT)

Protein Chromatography

Spectroscopy

Synthesis

Analytical Knowledge

Dissolution Testing

Formazione

PhD in Chemistry or related discipline

MS in Analytical Chemistry or related discipline with 5+ years experience

Strumenti

UHPLC/HPLC

Gas Chromatography

UV Spectroscopy

IR Spectroscopy

Karl Fischer Titration

Dissolution Testing

Descrizione del lavoro

Job Description We aspire to be the premier research-intensive biopharmaceutical company. Our company is at the forefront of research to deliver innovative health solutions that advance the prevention and treatment of diseases in people and animals.

The Analytical Commercialization Technology (ACT) group is seeking applicants for a Senior Scientist position available at the Rahway, NJ and West Point, PA sites. ACT is an R&D group responsible for analytical development of late-stage pharmaceutical products. The successful candidate will utilize innovative analytical characterization technologies to drive pharmaceutical drug product development and commercialization.

The Senior Scientist responsibilities include, but not limited to problem solving with the use of advanced analytical tools, data analysis with the use of statistical tools to drive product development and characterization, development and validation of robust analytical methods, drug product testing and analytical investigations in a cGMP environment, drug product and manufacturing process characterization, drug product stability studies, specification development, manufacturing process scale-up and validation support, preparation of Chemistry, Manufacturing, and Controls (CMC) documents for global regulatory submissions, and technology transfer for commercial manufacture. The successful candidate must be able to collaborate in a dynamic, integrated, and multidisciplinary team environment.

Responsibilities

• Utilize advanced analytical tools for problem-solving
• Analyze data for technical insights and trending
• Develop and validate robust analytical methods
• Conduct drug product testing and analytical investigations in a cGMP environment
• Drug product and manufacturing process characterization
• Drug product stability studies
• Specification development
• Manufacturing process scale-up and validation support
• Preparation of Chemistry, Manufacturing, and Controls (CMC) documents for global regulatory submissions
• Technology transfer for commercial manufacture
• Collaborate in a dynamic, integrated, and multidisciplinary team environment

Utilize advanced analytical tools for problem-solving Analyze data for technical insights and trending Develop and validate robust analytical methods Conduct drug product testing and analytical investigations in a cGMP environment Characterize drug products and manufacturing processes Perform drug product stability studies Develop specifications and support manufacturing process scale-up and validation Prepare Chemistry, Manufacturing, and Controls (CMC) documents for global regulatory submissions Facilitate technology transfer for commercial manufacture Collaborate in a dynamic, integrated, and multidisciplinary team environment

Qualifications

• Required PhD in Chemistry or related discipline with no experience required OR Master of Science (MS) in Analytical Chemistry or related discipline with at least five (5) years of relevant pharmaceutical development experience.
• Strong knowledge and hands‑on experience in chemistry and common analytical techniques
• Demonstrated problem-solving ability
• Excellent verbal and written communication skills
• Demonstrated creativity and strong interpersonal skills
• Ability to work in a team environment with cross-functional interactions

Preferred

• Strong background and extensive hands‑on experience with common analytical techniques such as Ultrahigh/High-Performance Liquid Chromatography (UHPLC/HPLC), Gas Chromatography, Ultraviolet (UV) and Infrared (IR) spectroscopy, Karl Fischer titration, and dissolution testing.

Required Skills

• Analytical Method Development
• Chemical Proteomics
• Chemical Synthesis
• Chemometrics
• Chromatography
• Data-Driven Decision Making
• Mass Spectrometry Based Proteomics
• Method Validation
• Motivation Management
• Process Analytical Technology (PAT)
• Protein Chromatography
• Spectroscopy
• Synthetic Biology

US and Puerto Rico Residents Only

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities.

Employee Status and Work Arrangements

• Employee Status: Regular
• Relocation: Domestic
• VISA Sponsorship: No
• Travel Requirements: 10%
• Flexible Work Arrangements: Not Applicable
• Shift: 1st - Day
• Valid Driving License: No
• Hazardous Material(s): n/a

Salary Range

The salary range for the primary location of this role is: $117,000.00 - $184,200.00. This range reflects the Company's reasonable expectation of the base salary applicable to this role at the time of posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs. The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

Benefits

Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days.

Additional Location(s)

Additional location(s): Please note the salary range above applies to the Primary Location of the position. Where a role has other listed locations, different compensation guidelines may apply. You may find the salary ranges for additional locations below. If the salary range is not listed for the location you are applying to, our Talent Acquisition team will provide further information to you relevant to your location. Additional location(s) Compensation Information: San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

Merck & Co., Inc.

Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Application Deadline

Job Posting End Date: 11/16/2026 *A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Our company is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products.

The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where we have codified our legacy for over a century.