Senior Research Technologist - Mills Lab

Mayo Clinic; Rochester (MN); On-site; USD 67,454 - 101,212; Full time

Benefits offered by this job

Medical plans

Dental coverage

Vision plan

HSA/FSAs

Retirement plan

Job summary

Mayo Clinic in Rochester, Minnesota seeks a Senior Research Technologist for a translational research laboratory focusing on neuroimmunology, biomarker discovery, and assay development. The role involves hands-on bench work, data analysis, and meticulous record-keeping in a fast-paced, collaborative environment.

Ideal candidates hold a BS in biology or chemistry with 4 years of lab experience; a Master’s is preferred.

Qualifications

• Requires a bachelor’s degree in biology, chemistry, or a related science with 4 years of research laboratory experience.
• Master’s degree in biology, chemistry, or related science preferred.
• Experience with 96-well plate–based assays or similar workflows is highly valued.
• Strong organizational skills and meticulous laboratory documentation are essential.
• Ability to work independently and within a collaborative team in translational research.

Responsibilities

• Perform routine and advanced laboratory procedures in support of research studies and assay development.
• Prepare reagents, buffers, samples, and laboratory materials.
• Conduct pipetting-intensive experiments and 96-well plate-based assays with precision.
• Maintain accurate laboratory notebooks and experimental records.
• Assist with optimization, validation, and troubleshooting of assays.
• Analyze data using Excel or RStudio and manage inventory and supplies.

Skills

Laboratory techniques

Pipetting

Data analysis

Documentation

Education

Bachelor's degree in biology/chemistry or related science

Master's degree preferred

Tools

Excel

RStudio

Job description

Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits Highlights

• Medical: Multiple plan options.
• Dental: Delta Dental or reimbursement account for flexible coverage.
• Vision: Affordable plan with national network.
• Pre-Tax Savings: HSA and FSAs for eligible expenses.
• Retirement: Competitive retirement package to secure your future.

Responsibilities

We are seeking a motivated and detail-oriented Senior Research Technologist to join a translational research laboratory focused on neuroimmunology, biomarker discovery, and development of advanced immunologic assays. The individual in this role will support ongoing research studies through hand-on laboratory work, experimental organization, data analysis, and maintenance of accurate laboratory records.

The ideal candidate is highly organized, dependable, intellectually curious, and comfortable working in a fast-paced research environment that bridges basic science and clinical applications.

Primary Responsibilities

• Perform routine and advanced laboratory procedures in support of research studies and assay development
• Prepare reagents, buffers, samples, and laboratory materials
• Conduct pipetting-intensive experiments and 96-well plate-based assays with precision and consistency
• Maintain accurate and organized laboratory notebooks and experimental records
• Assist with optimization, validation, and troubleshooting of laboratory assays
• Process and organize biological specimens according to laboratory protocols
• Analyze and organize experimental data using Excel, RStudio, or related software tools
• Assist with inventory management, ordering supplies, and maintaining laboratory organization
• Collaborate with laboratory staff, trainees, and investigators on ongoing projects
• Follow all laboratory safety, biosafety, and quality control procedures

Desired Characteristics

• Strong problem-solving and troubleshooting abilities
• Ability to learn new techniques quicklyReliable, organized, and self-motivated
• Strong communication skills
• Interest in translational medicine, immunology, or biomarker research

Environment

This position involves substantial hand-on laboratory work and interaction with multidisciplinary research teams in a collaborative academic medical center environment. The role offers opportunities to develop advanced laboratory and analytical skills while contributing to clinically impactful research projects.

Qualifications

Requires bachelor's degree in biology, chemistry, or other relevant science with 4 years of research laboratory experience. Master's degree in biology, chemistry, or other relevant science preferred.

Strong Preference Given To Those Who Have

• Prior hand-on laboratory bench experience
• Demonstrated proficiency with basic laboratory techniques and pipetting
• Experience working with 96-well plate-based assays or similar experimental workflows
• Strong organizational skills and attention to detail
• Ability to maintain thorough and accurate laboratory documentation
• Ability to work independently while also functioning effectively within a collaborative team environment

Preferred Qualifications

• Experience working with human cell lines
• Experience with flow cytometry
• Familiarity with immunologic or protein-based assays (ELISA, cell-based assays, immunofluorescence, etc.)
• Experience with data analysis using RStudio and/or Excel
• Prior exposure to translational, clinical, or neuroimmunology research environments
• Experience handling human biological specimens

Exemption Status

Exempt

Compensation Detail

Education, experience and tenure may be considered along with internal equity when job offers are extended.; $67,454 - 101,212 annually

Benefits Eligible

Yes

Schedule

Full Time

Hours/Pay Period

80

Schedule Details

M-F Day shift with occasional evening hours when necessitated by experiments/projects.

Weekend Schedule

No weekend shifts.

International Assignment

No

Site Description

Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law" . Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

Recruiter

Jill Squier