Senior Research Statistician - Exploratory Analysis (Hybrid)

AbbVie Inc.; South San Francisco (CA); Vor Ort; USD 140.000 - 210.000; Vollzeit

Benefits dieser Stelle

Health benefits

401(k) plan

Zusammenfassung

AbbVie Inc. is seeking a Senior Research Statistician to provide statistical support across drug discovery, target validation, and clinical biomarker exploration to enable precision medicine decisions.

You will work with discovery and translational teams on multi-dimensional data from discovery to late-stage development. The role emphasizes designing and analyzing biomarker studies, developing protocols, ensuring data quality, and communicating complex statistics to cross-functional partners in

Qualifikationen

• MS with 4+ years of experience or PhD with 0+ years in Statistics/Biostatistics.
• Experience in the pharmaceutical or healthcare space.
• Experience with Machine Learning.

Aufgaben

• Collaborate with discovery, translational biomarker scientists and clinicians to design, analyze and report biomarker studies for early and late-phase trials.
• Develop biomarker analysis plans and contribute to protocols for clinical trials and biomarker studies.
• Ensure data quality and integrity for statistical analyses and deliverables.
• Support pharmacology and translational science teams in detecting markers and signatures across omics/imaging data for precision medicine.
• Perform statistical analyses per the biomarker analysis plan and advise on study design issues under supervision.
• Communicate statistical concepts clearly to non-statisticians and support product teams with data-driven insights.

Kenntnisse

Machine Learning

Statistical Analysis

Biostatistics

Data Visualization

Ausbildung

MS in Statistics/Biostatistics

PhD in Statistics/Biostatistics

Tools

R

Python

SAS

Jobbeschreibung

Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, Xand YouTube.

Job Description

The Senior Research Statistician is responsible for providing statistical support to the research and development organizations for drug discovery, target identification/verification, non-clinical and clinical biomarker exploration to characterize subgroups of patients or markers of disease progression and treatment response for precision medicine. The Senior Research Statistician works under supervision to support discovery researchers, translational scientists and clinicians in the design, collection, analysis and reporting of multi-dimensional biomarker data from Discovery to late stage clinical development to enable objective decision-making for each drug development program.

Major Job Responsibilities

• Collaborating with discover and translational biomarker scientists and clinicians and contribute to design, analysis and reporting of biomarker and assay studies in association with early and late phase clinical trials. The typical analysis includes pharmacodynamic biomarker analysis, safety biomarker analysis, prognostic and predictive biomarker identification and development, bioassay and companion diagnostic test development, patient subgroup identification based on biomarkers and clinical variables.
• Contributing to design, analysis and reporting of biomarker-based clinical trials or other scientific research studies. Assist in developing biomarker section of clinical trial protocols or biomarker analysis plans. Working under supervision to implement sound statistical methodology in scientific investigations.
• Ensuring data are sensible and comprehensive with quality for the assigned statistical analysis and deliverables.
• Supporting and advising scientists in discovery and translational science units in the design, analysis and reporting of in vitro, in vivo pharmacology studies, and human clinical trials under supervision. Identify markers and signatures from internal/external omics/imaging and other biomarker data for target identification, mechanism of action, resistant mechanism, disease progression, patient selection and stratification for precision medicine.
• With Supervision perform statistical analyses as per the biomarker analysis plan. Bringing attention to supervisor and team for potential issues arising in the study design; conducting and proposing scientifically sound approaches. If assigned, evaluating appropriateness of available software for planned analyses and assessing pros and cons for potential development of novel statistical methodology.
• Accountability for data presentation and inference, with supervision. Collaborating in publication of scientific research. Ensuring that study results and conclusions are scientifically sound, clearly presented, and consistent with statistical analyses provided. Clearly explaining statistical concepts to non-statisticians. Provide responses to questions and pursue analyses suggested by data under supervision. Supporting communications between assigned product team(s) and functional management.

Qualifications

Minimum Job Qualifications:

• MS (with 4+ years of experience) or PhD (with 0+ years of experience) in Statistics, Biostatistics, or a highly related field.
• Research experience in the pharma or healthcare space
• Experience with Machine Learning

Preferred Qualifications

• Experience with Biomarker Research

Other Required Skills:

• High degree of technical competence and effective communication skills, both oral and written
• Able to identify data or analytical issues, and assist with providing solutions by either applying own skills and knowledge or seeking help from others
• Able to build strong relationship with peers and cross-functional collaborators to achieve higher performance. Highly motivated to drive innovation by raising the bar and challenging the status quo
• Able to integrate high dimensional data from different sources. Familiar with overfitting and multiple testing control methods, such as cross-validation and random resampling techniques. Familiar with machine learning and predictive modeling methods.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
• This job is eligible to participate in our short-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employer remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html