Senior Research Scientist, Evidence Synthesis Remote, United States

Precision Medicine Group; Northern (KY); Hybrid; USD 100,000 - 140,000; Full time

Benefits offered by this job

Discretionary bonus

Health insurance

Retirement savings

Life insurance

Disability benefits

Parental leave

Paid time off

Job summary

Precision Medicine Group is seeking a Senior Research Scientist, Evidence Synthesis, to lead complex evidence synthesis projects and collaborate across a multi-level team. You will develop study protocols, technical reports, and deliverables while mentoring junior staff and managing client communications.

The role emphasizes systematic reviews, indirect treatment comparisons, and HTA submissions, with a strong focus on strategic direction and project leadership.

Qualifications

• Master’s degree in health services research or related field.
• 4-6 years of professional experience in evidence synthesis or HTA submissions.

Responsibilities

• Develop deliverables such as protocols and technical reports.
• Handle day-to-day client communications and oversee junior researchers.
• Mentor team members and provide direction on project work.
• Lead and participate in client calls and contribute to proposals.

Skills

Systematic reviews

NMA/MAIC/STC

Client communication

Project management

Mentorship

Pharma industry knowledge

Education

Master’s degree

Tools

MS Office

EndNote

R

R Shiny

Job description

Senior Research Scientist, Evidence Synthesis

Remote, United States

Do you consider yourself a self-starter with a real passion for projects involving innovative methods in evidence synthesis? Do you love collaborating, moving the ball forward and rolling up your sleeves? We are growing and seeking a Senior Research Scientist with technical experience in systematic literature reviews and/or indirect treatment comparisons (e.g. NMA, MAIC, STC) for the purposes of health technology assessment submissions. We offer opportunities to work 100% remotely from Canada or the US.

Our culture is similar to that of a start-up, but in a well-funded established global portfolio organization. We pride ourselves on being leaders with vision in our field! Below are some examples of recent work we have published as part of our efforts to support our clients:

• Cope S, Chan K, Jansen JP. Multivariate network meta‐analysis of survival function parameters. Research synthesis methods. 2020;11(3):443-456. https://doi.org/10.1002/jrsm.1405
• Freemantle N, Xu Y, Wilson FR, et al. Network meta-analysis of immune-oncology monotherapy as first-line treatment for advanced non-small-cell lung cancer in patients with PD-L1 expression ≥50. Ther Adv Med Oncol. 2022; 14:17588359221105024. https://doi.org/10.1177/17588359221105024
• Watts, JM, Wang, ES, Jonas, BA, Wilson FR, et al. Matching-Adjusted Indirect Comparison of Olutasidenib and Ivosidenib in Isocitrate Dehydrogenase 1-Mutated Relapsed/Refractory Acute Myeloid Leukemia. Adv Ther. 2026;43:1802–1815. https://doi.org/10.1007/s12325-026-03522-6
• Keeping ST, Cope S, Chan K, et al. Comparative effectiveness of nivolumab versus standard of care for third-line patients with small-cell lung cancer. J Comp Eff Res. 2020;9(18):1275–1284. https://doi.org/10.2217/cer-2020-0134

Senior Research Scientists collaborate across a broad portfolio of sophisticated evidence synthesis projects in a multi-level team structure. Responsibilities include development of deliverables (e.g. study protocols and technical reports), handling day-to-day client communications, as well as delegating and overseeing tasks completed by junior researchers. This position will complete complex job responsibilities independently as well as provide mentorship and direction for others in delivering project work.

Essential functions for this role are:

• Subject Matter Expertise/Domain Knowledge
• Demonstrates understanding of the pharmaceutical industry, medical affairs, and requirements for health technology assessments
• Sufficient understanding of relevant methods to be able to oversee systematic literature reviews (clinical, economic, and/or health-related quality of life) and/or quantitative evidence synthesis studies
• Can identify considerations relevant to the synthesis of available evidence and communicate these within deliverables (e.g., feasibility assessments, statistical analysis plans)
• Develops client-ready deliverables including protocols, statistical analysis plans, technical reports, and slides
• Strategic Direction
• Contributes to short-term resourcing discussions
• Project Management
• Manages the delivery of components of projects by collaborating with other staff members to ensure high quality outputs
• Helps ensure timely delivery and financial performance of projects or project subcomponents
• Estimates required hours and identifies challenges early on and communicates any changes as well as viable solutions to project lead if necessary
• Client Management
• Reviews update slides/minutes and actions for overall study and viewed by client as independent researcher for specific study or component(s)
• Leads client calls and responds to emails, inviting input from senior team members with methodological/subject matter expertise where appropriate
• Line Management/Team Development
• Creates development plans and acts as a mentor for direct reports
• Business Development
• Contributes to development of proposals and presentations under guidance of more senior team members with methodological/subject matter expertise
• May also participate in meetings related to new business, including concept ideation

Minimum required experience for this role is:

• Master’s degree in a subject related to health services research e.g., health economics, public policy, health policy, epidemiology, biostatistics, public health, or science (biology/biochemistry etc.)
• 4-6 years’ professional experience

Core competencies required for this role are:

• Willingness and desire to learn and share knowledge
• Excellent oral and written communication skills
• Proficiency with Microsoft Office and EndNote
• Proficiency in R/R Shiny advantageous

Precision is required by law in some states or cities to include a reasonable estimate of the compensation range for this role. This compensation range takes into account the wide range of factors that are considered in making compensation decisions including but not limited to: skill sets, experience and training, licensure and certifications, and other business and organizational needs. The disclosed range estimate has not been adjusted for the applicable geographic differential associated with the location at which the position may be filled. At Precision, it is not typical for an individual to be hired at or near the top of the range for their role and compensation decisions are dependent on the facts and circumstances of each case. This role is also eligible for a discretionary annual bonus, health insurance, retirement savings benefits, life insurance and disability benefits, parental leave, and paid time off for sick leave and vacation, among other benefits.

Reasonable estimate of the current range

$100,000 - $140,000 USD

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