Senior Research Scientist, Biologics Development

Placements24

Riverton (UT)

À distance

USD 140 000 - 210 000

Plein temps

Il y a 3 jours
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Résumé du poste

Placements24 is seeking a Senior Research Scientist for our fully remote Biologics Development team. You will lead discovery-to-preclinical projects, applying protein engineering and biophysical characterization to advance novel biologics.

The role offers remote work with strong collaboration across discovery biology, CMC, and regulatory teams. Ideal candidates hold a PhD with 6+ years in biologics development, have hands-on experience with SPR, DLS, CD spectroscopy, and formulation studies, and

Qualifications

  • PhD with 6+ years in biologics development.
  • Proven protein/antibody engineering experience across discovery to preclinical.
  • Hands-on biophysical assays: SPR, DLS, CD, stability testing.
  • Strong data interpretation and scientific reporting skills.

Responsabilités

  • Lead research projects for development and optimization of therapeutic biologics.
  • Apply protein design to enhance properties of antibodies or proteins.
  • Develop biophysical assays to assess stability and function.
  • Design formulation studies for product stability and shelf-life.
  • Troubleshoot expression, purification, and downstream processing.
  • Collaborate with discovery biology, CMC, and regulatory teams.
  • Mentor junior scientists and contribute to strategic planning.

Connaissances

Protein engineering
Antibody engineering
Biophysical characterization
Formulation development
Data analysis
Remote collaboration

Formation

PhD in Biochemistry/Biophysics/Engineering/Biology

Outils

SPR
DLS
CD spectroscopy
Thermal shift
Protein expression systems

Description du poste

About the Role

Our client is a pioneering biopharmaceutical company focused on developing life-changing biologic therapies. We are seeking a highly experienced Senior Research Scientist to join our fully remote Biologics Development team. This role is central to the discovery, characterization, and optimization of novel protein-based therapeutics. The scientist will apply their deep understanding of protein engineering, biophysical characterization, and formulation science to advance our pipeline candidates. This is an exciting opportunity to work with a world-class team on impactful projects, driving innovation in the biopharmaceutical field from the comfort of your home. Our remote-first philosophy ensures seamless collaboration and productivity, enabling top talent to contribute from anywhere. We are committed to advancing cutting-edge biologics and require passionate individuals to join our mission.

Key Responsibilities
  • Lead and execute research projects focused on the development and optimization of therapeutic biologics.
  • Apply principles of protein engineering and design to enhance antibody or protein therapeutic properties.
  • Develop and perform advanced biophysical characterization assays (e.g., SPR, DLS, CD spectroscopy, thermal shift assays) to assess protein stability and function.
  • Design and conduct formulation development studies to ensure product stability and shelf-life.
  • Investigate and troubleshoot issues related to protein expression, purification, and downstream processing.
  • Collaborate closely with discovery biology, CMC, and regulatory affairs teams.
  • Analyze and interpret complex experimental data, and contribute to the preparation of technical reports and publications.
  • Stay abreast of the latest scientific advancements and technologies in biologics development.
  • Mentor and guide junior scientists and research associates.
  • Contribute to the strategic planning and direction of the biologics development group.
Requirements
  • Ph.D. in Biochemistry, Biophysics, Chemical Engineering, Molecular Biology, or a related field.
  • Minimum of 6 years of post-doctoral or industry experience in biologics development.
  • Proven expertise in protein engineering, antibody engineering, or protein therapeutic development.
  • Hands-on experience with a wide range of biophysical characterization techniques.
  • Strong understanding of protein expression, purification, and formulation science.
  • Experience with biologics development from discovery through to preclinical stages.
  • Excellent analytical, problem-solving, and critical thinking skills.
  • Strong written and verbal communication skills, with the ability to effectively present complex scientific information.
  • Demonstrated ability to work independently and lead research projects in a remote setting.
  • Experience with computational modeling and protein structure analysis is a plus.
  • A collaborative spirit and a track record of successful teamwork.
Benefits

This fully **Yes** remote position offers a highly competitive salary and an exceptional benefits package, including comprehensive health, dental, and vision insurance, a generous retirement savings plan, and significant opportunities for professional growth. Employees benefit from a flexible work schedule and the ability to contribute to groundbreaking research without geographical constraints. Our client provides access to state-of-the-art computational and data analysis tools, supporting continuous learning through online resources, workshops, and virtual conferences. This role offers substantial autonomy and the chance to make a significant impact on the development of novel therapeutics, fostering a rewarding career in biopharmaceutical innovation.

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