Senior Research Associate, Histology (Contract)

Flagship Pioneering, Inc.; Cambridge (MA); On-site; USD 108,886,000 - 146,136,000; Full time

Job summary

Mirai Bio, a Flagship-founded biotech, seeks a Senior Research Associate, Histology contractor to advance platform research in genomic medicine. You will process tissues for histology, perform in vitro assays, and help optimize immunohistochemistry readouts.

The role requires hands-on histology, cell culture, and strong documentation, with independent, cross-functional collaboration in a fast-paced, entrepreneurial setting.

Qualifications

• BS or MS in Biology, Biochemistry, Molecular Biology, or related scientific discipline.
• BS + 5 years or MS + 3 years of relevant experience in industry or research.

Responsibilities

• Perform histology processing of tissues and run plate-based assays.
• Review slides and data to optimize immune histochemistry readouts.
• Manage external CROs and vendors for histology assays.
• Develop and optimize assays based on lab techniques and data.
• Document assay results in electronic lab notebooks and reports.

Skills

Histology evaluation

In vitro cell assays

Cell culture

Independent work

Cross-functional collaboration

Effective communication

Education

BS in Biology/Biochemistry/Molecular Biology

MS in Biology/Biochemistry/Molecular Biology

Job description

COMPANY DESCRIPTION

Mirai Bio is a privately-held, Flagship-founded biotechnology company that is delivering genetic medicines from promise to performance. Mirai was built to solve one of the field’s central challenges: achieving precise, scalable delivery of diverse nucleic acid payloads to specific cells and tissues, particularly beyond the liver. By combining a large and growing proprietaryin vivobiodistribution dataset, machine learning-guided lipid nanoparticle optimization, modular targeted particle design, and integrated translation and manufacturing capabilities, Mirai helps partners accelerate development, reduce technical risk, and pursue high-value programs making delivery a strategic advantage. We are seeking collaborative, relentless problem solvers that share our passion for defining the future of genetic medicines together.

We are seeking a Senior Research Associate, Histology contractor to join the Platform Group at Mirai Bio to support laboratory research activities towards development of novel technologies enabling next generation genomic medicines. The successful candidate will have a strong understanding of the technical and equipment needs in a lab as well as significant hands-on experience with standard histology, cell culturing and in vitro cell biology techniques. They will work independently and as part of a collaborative team.

KEY RESPONSIBILITIES

• Performing laboratory assays and tasks including processing tissues for histology, plate-based reporter assays and additional in vitro assays
• Review data slides to streamline optimization and data analysis of immune histochemistry and immuno florescence readouts
• Help manage external vendors and CRO in support of histology assays
• Developing new assays or optimizing existing ones based on in-depth knowledge of laboratory techniques.
• Analyzing and accurately documenting assay results in an electronic lab notebook or other technical reporting formats

PROFESSIONAL EXPERIENCE & QUALIFICATIONS

• BS or MS in Biology, Biochemistry, Molecular Biology, or related scientific discipline
  • BS + 5 years of relevant industry or research experience
  • MS + 3 years of relevant industry or research experience
• Previous experience with histology evaluation and in vitro cell based assays is required
• Strong cell culture experience, including experience executing protocols, troubleshooting assays is preferred
• Prior experience working with lipid nanoparticles is a plus
• Proven ability to work independently and cross-functionally with highly skilled teams in a fast-paced, entrepreneurial, and technical environment
• Strong organizational and problem-solving skills
• Motivated, curious, and comfortable working with highly technical projects and personnel
• Excellent communication and presentation skills, capable of conveying technical information in a clear and thorough manner

ABOUT FLAGSHIP PIONEERING:

Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.

We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.

We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.

The salary range for this role is $38 - $51. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Mirai Bio currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Mirai Bio’s good faith estimate as of the date of publication and may be modified in the future.