Senior R&D Chemist – Nucleoside Synthesis & QC

Sarmal Inc; San Diego (CA); On-site; USD 72,000 - 85,000; Full time

Benefits offered by this job

Medical, dental, and vision coverage

Company-paid life insurance

401(k) retirement plan

Generous paid time off

Employee perks and discount programs

Job summary

Sarmal, Inc. in San Diego, CA is seeking a Chemistry R&D Senior Research Associate to execute synthesis, purification, characterization, and QC analysis of novel modified nucleoside/nucleotide motifs. The role demands hands-on lab work with sensitive compounds and complex purification techniques.

You will contribute to upstream materials development foundational to the core technology, work in a fast-paced, cross-functional team, and document results with rigorous scientific communication.

Qualifications

• Hands-on experience with organic synthesis and purification techniques.
• Experience handling air- and moisture-sensitive reactions under inert atmosphere.
• Proficiency with LC-MS, NMR, IR, UV/Vis and related analytical methods.

Responsibilities

• Synthesize modified nucleosides/nucleotides using diverse synthesis techniques.
• Purify products via preparative HPLC, flash chromatography, and other methods.
• Characterize compounds using LC-MS, NMR, IR, UV/Vis, TLC; analyze data.

Skills

Organic synthesis

Air- and moisture-sensitive reactions

LC-MS

NMR

Analytical chemistry

Documentation

Team collaboration

Communication

Education

B.S. or M.S. in inorganic chemistry or related discipline

Tools

Preparative HPLC

LC-MS

NMR

IR

UV/Vis

Job description

Sarmal, Inc. in San Diego, CA is seeking a Chemistry R&D Senior Research Associate to execute synthesis, purification, characterization, and QC analysis of novel modified nucleoside/nucleotide motifs. The role demands hands-on lab work with sensitive compounds and complex purification techniques.

You will contribute to upstream materials development foundational to the core technology, work in a fast-paced, cross-functional team, and document results with rigorous scientific communication.