Senior QC Chemist – GMP, HPLC & Wet Chemistry

Actalent; St. Louis (MO); On-site; USD 38,000 - 40,000; Full time

Benefits offered by this job

Medical, dental & vision

401(k) Retirement Plan

Paid time off

Life Insurance

Job summary

Actalent is seeking a QC Chemist III in St. Louis to perform wet chemistry and analytical testing on raw materials within a GMP-regulated pharmaceutical facility. You will operate HPLC, GC, UV, pH meters, and related lab equipment, ensuring instrument readiness and precise data entry in LIMS.

The role emphasizes thorough documentation, investigations, and collaboration with cross-functional teams to drive quality, safety, and continuous improvement in laboratory operations.

Qualifications

• BS degree in a STEM discipline.
• 13 years of industry experience in a GMP-regulated environment.
• 13 years of HPLC experience in a GMP-regulated environment.
• Hands‑on experience with wet chemistry techniques.
• Working knowledge of analytical instrumentation, especially GC and LC, including basic troubleshooting.
• Experience performing quality control testing in a pharmaceutical or similar regulated setting.
• Proficiency with LIMS for data entry and management.
• Ability to follow good documentation practices and maintain accurate, compliant records.
• Good technical writing skills for documenting investigations, results, and reports.
• Strong oral communication skills for effective interaction with colleagues and stakeholders.
• Basic computer skills and familiarity with Microsoft Office Suite.
• Experience using Chromeleon or other chromatography data systems.

Responsibilities

• Perform wet chemistry and analytical testing on raw materials in accordance with established procedures and GMP requirements.
• Operate and maintain analytical instruments, including HPLC, GC, UV, pH meters, analytical balances, and related laboratory equipment.
• Ensure instrument readiness by performing routine checks, basic troubleshooting, and documenting maintenance activities.
• Follow good documentation practices to record all laboratory activities accurately, completely, and in a timely manner in laboratory notebooks, LIMS, and other systems.
• Enter and manage analytical data in LIMS, ensuring data integrity, traceability, and compliance with internal and regulatory standards.
• Conduct laboratory investigations, including root cause analysis and documentation, to resolve testing issues and support corrective and preventive actions.
• Peer review analytical data, calculations, and documentation to ensure accuracy, completeness, and adherence to procedures.
• Support and follow site Health, Safety, and Environmental (HSE) policies and procedures to maintain a safe laboratory environment.
• Assist in establishing, implementing, and maintaining safe work standards and best practices in the laboratory.
• Collaborate with cross-functional teams to support quality control activities, resolve testing challenges, and improve laboratory processes.
• Communicate test results, issues, and findings clearly and professionally to relevant stakeholders.
• Contribute to continuous improvement initiatives by identifying opportunities to enhance efficiency, quality, and safety in laboratory operations.

Skills

GMP experience

HPLC experience

Wet chemistry

Data analysis

Written communication

Team collaboration

Education

Bachelor of Science in STEM

Tools

HPLC

GC

UV

LIMS

Chromeleon

Job description

Actalent is seeking a QC Chemist III in St. Louis to perform wet chemistry and analytical testing on raw materials within a GMP-regulated pharmaceutical facility. You will operate HPLC, GC, UV, pH meters, and related lab equipment, ensuring instrument readiness and precise data entry in LIMS.

The role emphasizes thorough documentation, investigations, and collaboration with cross-functional teams to drive quality, safety, and continuous improvement in laboratory operations.