Senior Project Manager

Actalent; Frederick (MD); Remote; USD 147,000 - 200,000; Full time

Benefits offered by this job

Medical coverage

Dental coverage

Vision coverage

401(k) match

PTO

Parental leave

Life insurance

HSA contributions

Wellness program

Job summary

Actalent is hiring a Sr. Clinical Project Manager for a 100% remote role. The candidate will lead global oncology-focused trials from start-up to closeout, coordinating with vendors and clients while ensuring scope, quality and financial health.

This senior position requires 7+ years in clinical research and 4+ years of CRO PM experience, with travel as needed. The role is remote with global responsibilities and a base out of Frederick, MD.

Qualifications

• 7+ years of clinical research experience with 4+ years in CRO project management.
• Bachelor’s degree in science or health-related field; advanced degree preferred.
• Strong oncology experience with radiopharmaceuticals, CAR-T or cell therapy preferred.
• Willingness to travel domestically and internationally.

Responsibilities

• Serve as the primary contact and escalation point for assigned projects with clients.
• Coordinate and oversee external vendors to meet timeline and budget.
• Manage study budget, out-of-scope activities, change orders, and forecasting.
• Collaborate with clinical operations to deliver activities and provide full-study coverage as needed.
• Monitor project profitability and billable hours to support business objectives.
• Develop detailed project plans, timelines, and risk management strategies.
• Ensure quality management, eTMF readiness, and CAPAs as needed.
• Review study documentation with cross-functional teams for alignment.
• Prepare status updates and KPIs for clients and Sr management.
• Lead internal and client meetings to set scope, timelines, and roles.
• Communicate protocol and study issues to clients and management, and implement corrective actions.
• Deliver formal presentations to diverse audiences and participate in bid defenses.
• Ensure project-specific training across functions and monitor compliance.
• Support business development and travel to client meetings as required.
• Perform other duties to support objectives and maintain compliance.
• Provide feedback and mentorship to team members.

Skills

CRO PM experience

Oncology trials

Budget & forecasting

Client leadership

Global trials

Education

Bachelor's in science/health

Job description

Position: Sr. Clinical Project Manager (Homebased/100% Remote)

*MUST HAVE 4+ YEARS OF RECENT PROJECT MANAGEMENT EXPERIENCE FROM A CRO!!

The Sr Project Manager plans, directs, coordinates, and delivers all activities for designated clinical study projects to ensure that objectives of quality, scope, cost, and time are consistently achieved. This role focuses on full-service clinical research organization (CRO) project management, with a strong emphasis on oncology studies, and requires a confident client-facing leader who can drive complex, global trials from start-up through closeout while maintaining rigorous quality and financial oversight.

Responsibilities

• Serve as the primary point of contact and primary escalation point for assigned clinical study projects, ensuring clear, timely, and professional communication with the client.
• Coordinate and oversee all functional services, including external vendors, to ensure delivery against the established project timeline and budget.
• Manage the overall study budget, ensuring projects remain within scope and that any out-of-scope activities are identified early, documented, and handled appropriately, including independently driving change orders to completion and execution with support as needed.
• Maintain close collaboration with clinical operations to support the delivery of clinical activities and, for projects of limited scope, assume responsibility for all clinical activities as needed.
• Manage the financial health of assigned studies, including oversight of project profitability, billable project hours, and compliance with on-time, accurate billing and forecasting to support business objectives.
• Develop robust and comprehensive project plans, including detailed timelines and proactive risk management and mitigation strategies, to guide all aspects of trial execution with consistency and quality.
• Ensure quality management for assigned projects, including maintaining eTMF inspection readiness and implementing quality notification incident forms and/or corrective and preventative action plans to address quality findings.
• Collaborate with all functional operations to support program delivery and review study documentation as necessary to ensure alignment and quality.
• Establish tracking metrics and performance indicators to monitor trial and team progress toward project goals and to identify risks or issues early.
• Prepare clear project status updates and progress reports for clients and Sr management, including reporting on key performance indicators and proposing solutions and improvement opportunities as they arise.
• Lead both internal and client-facing meetings, set expectations for the project team, and ensure alignment on scope, timelines, deliverables, and roles.
• Communicate effectively with clients and internal management to relay protocol and study issues, including any deviations, and implement appropriate actions in response.
• Conduct formal presentations to a wide variety of audiences, including colleagues, investigative site staff, and clients, and participate in bid defense meetings with strong presentation proficiency.
• Ensure implementation of study-specific training in collaboration with functional areas and monitor ongoing training compliance for the duration of each project.
• Support business development and marketing activities as appropriate, including traveling to bid defense and other client meetings as required.
• Perform other duties as assigned by management to support project and organizational objectives.
• Remain compliant with organizational requirements for training, time reporting, and other administrative duties.
• Provide ongoing feedback to functional team members, including contributing to annual performance reviews, and demonstrate leadership through mentorship, escalation handling, and influence without direct authority.

Additional Skills & Qualifications

• Extensive full-service CRO project management experience, with a clear track record of owning end-to-end delivery rather than only functional service provider (FSP) responsibilities.
• Strong oncology project management experience, with priority given to experience in radiopharmaceuticals, CAR-T or cell therapy, and general oncology, in that order.
• Minimum of 7 years of clinical research experience or proven competencies equivalent to this level, including a minimum of 4 years of direct project management experience FROM A CRO!!
• Bachelors degree in a science or health-related field, or an equivalent combination of education and experience; advanced degree preferred (North America and EU).
• Ability to travel domestically and internationally, including overnight stays, to support client meetings, bid defenses, and study oversight.

Job Type & Location

This is a Permanent position based out of Frederick, MD.

Pay and Benefits

The pay range for this position is $147300.00 - $200000.00/yr.

Individual compensation offered for this position within this range will depend on many factors, including qualifications, skills, relevant experience, job knowledge, geographic location, internal equity, and other pertinent job-related factors.

Comprehensive Medical, Dental & Vision Coverage - Generous employer contributions for employees and dependents, national Aetna plans, telehealth access, Delta Dental PPO options, and VSP vision coverage. 401(k) with Strong Employer Match - 4% employer match plus immediate 100% vesting through a Safe Harbor plan. Flexible Time Off - Exempt employees receive uncapped "My Time" (MTO), while non-exempt employees receive 20 days PTO annually, paid holidays, personal days, and volunteer time off. Family Planning & Parental Support - Infertility coverage, 8 weeks of paid maternity leave at 100% pay, 4 weeks of paid parental bonding leave, and up to $3,000 in adoption assistance per child. Company-Paid Life & Disability Insurance - Basic life insurance and AD&D up to 1.5x salary (maximum $500,000) plus short- and long-term disability coverage at 60% of pay. Health Savings Account (HSA) Contributions - Employees enrolled in the HDHP receive annual employer HSA contributions of $1,000 (individual) or $1,500 (family/employee-plus coverage). Wellness & Employee Assistance Programs - Free 24/7 support through Headspace, including mental health resources, counseling support, legal/financial assistance, work-life services, and access to over 3,000 wellness resources

Job Type & Location

This is a Permanent position based out of Frederick, MD.

Application Deadline

This position is anticipated to close on Oct 31, 2026.

Workplace Type

This is a fully remote position.

About Actalent

Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 20,000 consultants and 5,000 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500. We are proud to be an Engineering News-Record (ENR) Top 500 Design Firm for our engineering design services and a ClearlyRated Best of Staffing® winner for both client and talent service.

The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.

If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing process due to a disability, please email [e-mail] for other accommodation options.

San Francisco Fair Chance Ordinance: Pursuant to the San Francisco Fair Chance Ordinance, for all positions located in the city and county of San Francisco, we will consider for employment qualified applicants with arrest and conviction records.

Massachusetts Lie Detector: It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Use of Artificial Intelligence (AI): We may use Artificial Intelligence (AI) to support parts of our hiring process, including sourcing, screening, and evaluating candidates. AI helps assess applications and qualifications, but final decisions are made by our hiring team. By applying, you acknowledge and agree that your application may be reviewed using AI tools.