Senior Program Manager (SPM) - Mastocytosis

BioSpace; Cambridge (MA); On-site; USD 120,000 - 160,000; Full time

Job summary

Sanofi in Cambridge, MA seeks a Senior Program Manager for the Mastocytosis Therapeutic Area to drive lifecycle management initiatives and coordinate cross-functional teams across internal and external partners. You will partner with the Medical Program Lead and GMT to ensure on-time, compliant delivery of strategic programs.

The role requires a strong biotech/pharma project management background, excellent communication, and the ability to operate in a matrix environment while maintaining

Qualifications

• BS required; advanced degree preferred.
• Minimum 5 years of project/program management experience within biotech/pharma or scientific environments.
• Medical Affairs experience preferred.
• Strong ability to translate strategic objectives into actionable tactical plans.
• Proven track record of managing complex, cross-functional programs from initiation through completion with minimal supervision.

Responsibilities

• Lead program management initiatives for Mastocytosis in partnership with the Medical Program Lead (MPL).
• Collaborate with Global Medical Director to operationalize GMT strategies and deliverables.
• Drive integrated evidence generation planning through cross-functional partnerships with GMT, Brand teams, and functional leads.
• Manage Company-Sponsored Studies (CSS), Investigator-Sponsored Studies (ISS) & Real-World Evidence (RWE) activities and budgets.
• Ensure adherence to study compliance requirements and regulatory guidelines.
• Optimize cross-functional communication and stakeholder engagement to improve decision-making.
• Utilize harmonized Program Management Tools to manage portfolio-level activities across the organization.

Skills

Program management

Cross-functional collaboration

Communication

Organization

Leadership

Medical Affairs experience

Education

Bachelor of Science

Advanced degree

Tools

MS Project

SharePoint Apps

MS Office Suite

Job description

Job title: Senior Program Manager - Mastocytosis

Location: Cambridge, MA

About The Job

The Senior Program Manager (SPM) will drive business-related initiatives within the Mastocytosis Therapeutic Area (TA), serving as a key operational partner to the Medical Program Lead (MPL) and the Mastocytosis Global Medical Team (GMT).

Working collaboratively with internal stakeholders and external Alliance partners (where applicable), the SPM will ensure seamless execution of lifecycle management (LCM) initiatives, launch deliverables, and strategic programs aligned with product development stages.

Operating within a dynamic matrix environment, the SPM will coordinate cross-functional resources and activities to deliver on priorities outlined in the Global Medical Plans, ensuring strategic alignment and operational excellence across all TA-specific initiatives.

Join the engine of Sanofi's mission where deep immuno-science meets bold, AI-powered research. In R&D, you'll drive breakthroughs that could turn the impossible into possible for millions.

About Sanofi

We're an R&D-driven, AI-powered biopharma company committed to improving people's lives and delivering compelling growth. Our deep understanding of the immune system and innovative pipeline enables us to invent medicines and vaccines thattreat and protect millions of people around the world. Together, we chase the miracles of science to improve people's lives.

Main Responsibilities

Strategic Partnership & Leadership

Lead program management initiatives for Mastocytosis in strategic partnership with the Medical Program Lead (MPL)

Collaborate with Global Medical Director to operationalize Global Medical Team strategies and deliverables

Drive integrated evidence generation planning through cross-functional partnerships with Global Medical Directors, Brand teams, and functional leads

Study Lifecycle & Portfolio Management

• Company-Sponsored Studies (CSS):Manage approval process and serve as central Medical liaison for Clinical Sciences and Operations (CSO) communications and partnerships
• Investigator-Sponsored Studies (ISS) & Real-World Evidence (RWE):Partner with key stakeholders to capture operational details, study milestones, and budget requirements aligned with Medical plans
• Compliance & Reporting:Ensure adherence to study compliance requirements

Operational Excellence & Process Management

Optimize cross-functional communication and decision-making through meeting facilitation and stakeholder engagement

Streamline operational workflows to ensure compliance with internal SOPs and external regulatory guidelines

Utilize harmonized Program Management Tools to manage portfolio-level activities across the Program Management organization

Stakeholder & Alliance Partner Engagement

Build and maintain strategic partnerships with internal teams and external collaborators

Serve as primary advocate for alliance partner relationships (where applicable), ensuring alignment with collaboration objectives and deliverables

Provide specialized program management support for Therapeutic Area-specific initiatives and strategic priorities

About You

Basic Qualifications

The ideal candidate brings a strong foundation in the biotech/pharmaceutical industry, combined with proven expertise in Project/Program Management. A scientific background and Medical Affairs experience are highly preferred.

Education

• Bachelor of Science (BS) required
• Advanced degree in a scientific discipline strongly preferred

Experience

• Minimum 5 years of project/program management experience within biotech/pharma, clinical, or scientific environments
• Demonstrated ability to translate strategic objectives into actionable tactical plans
• Proven track record of managing complex, cross-functional programs from initiation through completion with minimal supervision
• Medical Affairs experience preferred

Core Competencies

Program Management Excellence

• Deep understanding of project/program management methodologies, frameworks, and best practices
• Skilled in end-to-end project ownership, including scope, timelines, risk management, and budget oversight
• Proficient in developing and maintaining reporting dashboards with key performance metrics using harmonized organizational tools

Leadership & Collaboration

• Demonstrated ability to lead and influence cross-functional teams within a matrix environment
• Strong management skills with the ability to engage effectively at all organizational levels
• Proven ability to foster a culture of teamwork, accountability, and collaboration

Communication & Organization

• Exceptional interpersonal and communication skills, both written and verbal
• Highly organized with the ability to manage competing priorities and tight deadlines with professionalism and composure
• Comfortable operating in a fast-paced, dynamic environment with shifting priorities

Technical Skills

• Advanced proficiency in Microsoft Office Suite (Word, Excel, PowerPoint, Outlook)
• Working knowledge of project/program management software (e.g., SharePoint Apps, MS Project, or equivalent tools)

Why Choose Us?

Bring the miracles of science to life alongside a supportive, future-focused team.

Discover endless opportunities to grow your talent and drive your career, whether it's through a promotion or lateral move, at home or internationally.

Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks' gender-neutral parental leave.

Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs.

Work at the forefront of drug discovery, harnessing cutting‑edge AI, data, and digital platforms to push the boundaries of science.

Help improve the lives of millions of people globally by making drug development quicker and more effective.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affectional Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.