Senior Product Manager, Oncology

BillionToOne Inc.; Menlo Park (CA); Hybrid; USD 174,000 - 196,000; Full time

Benefits offered by this job

Equity options

401(k) match

Fully paid parental leave

Healthcare benefits

Job summary

BillionToOne, a leader in genomics, is seeking a Senior Product Manager, Oncology to lead Northstar Select assay development and enhancements. You will partner with R&D, clinical, engineering, sales, marketing and leadership in a hybrid onsite-3-days-per-week role reporting to the Head of Product, Oncology.

You will own product concepts, plan launches, design end-to-end UX for the entire sample-to-result workflow, and drive program management with cross-functional teams; experience with

Qualifications

• 5–10 years of product management experience, commensurate with role
• Experience shaping product vision, GTM strategy and requirements
• Experience launching a product from start to finish
• Ability to align diverse teams to launch a complex product
• Experience with IVD product management
• Experience with NGS-based diagnostic assays is a strong plus
• Experience with clinical genetic testing products is a plus

Responsibilities

• Understand market and design a winning product concept as the domain expert
• Plan and execute product launches across core assay, apps and workflows
• Own end-to-end user experience from order to result
• Drive program management, timelines, and cross-functional alignment
• Continuously capture user feedback and market trends for improvements

Skills

Product management

Go-to-market strategy

Product requirements

Launching products

IVD / molecular diagnostics

NGS-based assays

Clinical genetics products

Oncology experience

Education

Masters/PhD in molecular biology or related

Job description

A Rare Opportunity to Shape the Future of Genomics

Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.

Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.

If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.

We are looking for a Senior Product Manager, Oncology to lead and manage our therapy selection product family, Northstar Select. This role will be working closely with R&D, clinical, engineering, sales, marketing, and company leadership to lead new assay development as well as existing assay enhancements. The ideal candidate has experience launching molecular diagnostic testing assays (including FDA-approved assays), is obsessed with delivering a delightful customer experience, and thrives in a fast-paced entrepreneurial environment. This role is an hybrid (onsite 3 days/week) position and reports directly to the Head of Product, Oncology.

Responsibilities:

• Understand the market and design a winning product concept: As the product owner, you need to be Number 1 expert within the company about the user needs and desires, the market, and how our technology assets can solve their problems.
• Plan and execute product launch: Understand and plan for every element that touches the product launch, including the core clinical assay, the user-facing software apps, the internal workflow, regulatory and legal constraints, and requirements, and support teams focused on marketing and PR activities, etc. Work with a wide range of departments to execute on the product launch.
• End-to-end user experience: Our product is not just the genetic testing panel but the entire experience of ordering a test, sending the blood sample, and receiving the result. You are responsible for designing and delivering the most seamless and delightful user experience for the entire process, together with a UX designer and other stakeholders.
• Program management: You are responsible for getting the product to the finish line by mobilizing relevant internal and external resources. This can involve many elements of general project and program management tasks such as driving timelines, getting stakeholders to agree on a solution, sourcing external vendors, etc.
• Continuous iterations and improvements: As the product owner, you are the biggest advocate for the users. You are responsible for monitoring the users' voice and behaviors, the key metrics, and key market trends for the product-line and identify areas of improvement.

Qualifications:

• 5-10 years of experience in product management (title & compensation commensurate with experience)
• Experience driving product vision, go-to-market strategy, and product requirements
• Experience with launching a product from start to finish
• Experience working with diverse teams to gather requirements and rally them to get a complex product launched
• Experience with IVD product management
• Experience with launching and managing NGS-based diagnostic testing assays is a strong plus
• Experience with launching and managing clinical genetic testing products is a huge plus

Nice-To-Haves:

• Oncology Experience a plus
• Another advanced degree (Masters/PhD) in molecular biology, bioengineering, medicine, chemical biology, or a related field is strongly preferred
• Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousands patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
• Extremely generous Family Bonding Leave for eligible employees (16 weeks, paid at 100%)
• Supplemental fertility benefits coverage
• Retirement savings program including a 4% Company match
• Increase paid time off with increased tenure
• Latest and greatest hardware (laptop, lab equipment, facilities)
• Free daily on-site lunches provided from top eateries
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of a base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).

The base salary range for this role is $174,068 - $195,826. This position is eligible for an annual bonus and receives a new hire equity grant of up to $90,000 at grant value, vesting over four years, plus annual equity refresh grants equal in value to the new hire grant. Together, the total four-year value of base, target bonus, and equity is up to approximately $1.1 million. We also offer competitive medical and dental coverage and a 401(k) with company match.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

For more information about how we protect your information, we encourage you to review our Privacy Policy .

BillionToOne is a next-generation molecular diagnostics company on a mission to make powerful, accurate diagnostic tests accessible to everyone. Our revolutionary QCT molecular counting technology enhances disease detection resolution by over a thousandfold using cell-free DNA,a breakthrough that has already transformed the lives of over half a million patients worldwide.

Our Impact

Unity Complete™ is the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample.
Unity Confirm™ enables non-invasive confirmation for high-risk screening results through the capture of intact circulating fetal cells using BillionToOne’s Fetal Cell Capture™ Technology.
Our Northstar® liquid biopsy test uniquely combines treatment selection with real-time monitoring, giving oncologists unprecedented precision in cancer care.

Our Growth

From $0 to $400M+ annualized revenue run-rate in just 6 years. In 2025, we completed one of the most successful IPOs for a medical diagnostics company, building on nearly $400M in private funding,including our $130M Series D in 2024 and backed by world-class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest.

Our Recognition

Forbes named us one of America's Best Startup Employers for 2025 and we're Great Place to Work certified, with 100% of our people willing to go the extra mile, even as we've scaled to over 700 employees.

Our Future

Headquartered in Menlo Park with facilities in Union City, CA, and a new lab opening in Austin, TX in 2027, we're continuing to push the boundaries of what's possible in molecular diagnostics. We're just getting started.

Ready to help us change the world, one molecule at a time? Learn more at billiontoone.com