Senior Process Chemist - Discovery & Scale-Up

Treelinebiosciences; San Diego (CA); On-site; USD 166,380 - 189,533; Full time

Job summary

Treeline Biosciences is seeking an experienced Senior Scientist / Principal Scientist in Process Chemistry to advance the development of small molecule drugs. This role emphasizes modern synthetic methodologies and collaboration with teams in drug discovery.

The ideal candidate will hold a Ph.D. in Organic Chemistry with strong expertise in synthetic chemistry, and the ability to manage complex projects while ensuring clinical supply readiness. The expected salary range for this position in San Diego is between $166,380 and $189,533.

Qualifications

• 3-8+ years of relevant industry or postdoctoral experience.
• Strong expertise in synthetic organic chemistry and reaction development.
• Experience managing external CDMO partners.

Responsibilities

• Collaborate with medicinal chemistry partners for candidate selection.
• Design and execute synthetic strategies for drug candidates.
• Support multi-gram to kilogram-scale synthesis.

Skills

Synthetic organic chemistry

Route design

Cross-functional collaboration

Project leadership

Education

Ph.D. in Organic Chemistry or related discipline

Tools

High-throughput experimentation

Flow chemistry

Job description

Treeline Biosciences is seeking an experienced Senior Scientist / Principal Scientist in Process Chemistry to advance the development of small molecule drugs. This role emphasizes modern synthetic methodologies and collaboration with teams in drug discovery.

The ideal candidate will hold a Ph.D. in Organic Chemistry with strong expertise in synthetic chemistry, and the ability to manage complex projects while ensuring clinical supply readiness. The expected salary range for this position in San Diego is between $166,380 and $189,533.