Senior Principal Statistical Programmer

WCG Clinical; City of Albany (NY); A distancia; USD 131.000 - 160.000; Jornada completa

Descripción de la vacante

WCG Clinical, Inc. in a US-Remote setting seeks a Senior Principal Statistical Programmer to lead statistical programming for clinical trials and DMC deliverables. You will design, develop, validate, and standardize high-quality outputs while guiding junior staff and influencing programming standards.

This role requires 8–10 years of experience, deep SAS expertise, proficiency in R, and CDISC knowledge. You will partner with biostatistics, data management, and study teams to ensure regulatory

Formación

• Master’s degree required, in a related field; equivalent experience considered.
• 8–10+ years of statistical programming in a clinical trial environment.
• Deep SAS programming experience for regulatory deliverables.
• Proficiency in R programming and CDISC standards.
• Proven ability to independently lead complex programming efforts.
• Experience mentoring staff and driving technical standards.
• Ability to coordinate biostatistical projects with minimal direction.

Responsabilidades

• Design, develop, validate, and oversee complex statistical programming deliverables.
• Lead development and standardization of DMC macros and programming standards.
• Provide technical oversight for programming work to ensure quality and regulatory alignment.
• Drive programming standards, best practices, and process improvements.
• Collaborate with biostatistics and study teams on complex trial designs.
• Mentor programming staff and support skill development.
• Coordinate programming activities across multiple studies with minimal direction.

Conocimientos

SAS programming

R programming

CDISC standards

Lead programming projects

Mentor staff

Educación

Master’s degree in biostatistics or related field

Herramientas

SAS environments

Regulatory submission tools

Descripción del empleo

About WCG

WCG delivers transformational solutions that accelerate clinical research and advance human health. We serve the experts, innovators, and pathfinders on the frontlines of science and medicine—empowering them to develop breakthrough therapies while ensuring the risks of progress never outweigh the value of human life. Together, we stimulate growth, maximize efficiency, and shape the future of clinical trials.

Why WCG

At WCG, we invest in our people because you are the driving force behind our mission. When you grow, our impact grows. When you thrive, research accelerates. We empower you to build a meaningful career while advancing the work that improves lives.

What we offer:

Comprehensive health and financial protection – Medical, dental, vision, life and disability insurance, 401(k) with company match, and flexible spending accounts

Resources that support your whole life – Employee assistance programs and work/life balance tools

Investment in your growth – Referral bonuses, tuition reimbursement, on-the-job training, certification assistance, and continuing education support

Time to recharge – Paid holidays, vacation, and sick time

Pathways forward – Career development opportunities across One WCG

We practice transparency in everything we do, including compensation. The salary range for this position reflects our commitment to fair, competitive pay based on your qualifications, experience, skills, education, and location. Together, we'll find the right fit for your expertise and our shared mission.

Job Summary

The Senior Principal Statistical Programmer serves as a senior technical leader and subject matter expert in statistical programming, with deep expertise supporting clinical trials and Data Monitoring Committee (DMC) deliverables. This role combines advanced hands-on programming capabilities with technical leadership, driving the design, development, and standardization of high-quality statistical outputs. The Senior Principal Statistical Programmer independently leads complex programming initiatives, provides expert-level guidance across projects, and plays a key role in shaping programming standards, tools, and best practices. This role partners closely with biostatistics, project management, data management and cross-functional stakeholders to ensure high-quality, compliant, and efficient delivery of programming outputs.

ESSENTIAL DUTIES/RESPONSIBILITIES: To perform this job successfully, an individual must be able to perform each essential duty and responsibility satisfactorily. The accountabilities listed below are representative of the knowledge, skills, and/or ability required.

• Serve as a senior technical expert in statistical programming, providing guidance across multiple studies or functional areas.
• Design, develop, validate, and oversee complex statistical programming deliverables, including analysis datasets, tables, listings, and figures.
• Lead the development, validation, and continuous improvement of DMC macros and programming standards.
• Provide technical oversight and review of programming work to ensure quality, compliance, and consistency across deliverables.
• Drive the establishment and adoption of programming standards, best practices, and process improvements.
• Collaborate with biostatistics and study teams to support complex trial designs, analyses, and DMC reporting.
• Independently manage and prioritize programming activities across multiple studies or initiatives.
• Mentor and provide technical leadership to statistical programming staff, supporting skill development and best practices.
• Contribute technical expertise to proposals, project planning, and scope discussions as needed.
• Partner with IT and technology teams to support SAS environments, tools, and system validation efforts.
• Provide technical oversight for programming activities supporting regulatory submissions and inspection readiness.
• Ensure programming deliverables align with regulatory expectations, submission requirements, and CDISC standards.
• Influence programming approaches, standards, and best practices across multiple studies or programs.
• Serve as a technical escalation point for complex programming, data, or deliverable issues, leading resolution of highly complex or ambiguous challenges.
• Provide expert interpretation of statistical analysis plans (SAPs), protocols, and study documents, translating requirements into programming strategy.
• Champion process improvements, automation, and innovative approaches to enhance efficiency, scalability, and consistency of programming deliverables.
• Other duties as assigned by supervisor. These may, on occasion, be unrelated to the position described here.

EDUCATION REQUIREMENTS: Master’s degree required. In limited circumstances, an equivalent combination of education and directly relevant professional experience may be considered.

QUALIFICATIONS/EXPERIENCE:

• Minimum 8–10 years of statistical programming experience in a clinical trial environment.
• Deep expertise in SAS programming, including complex analyses and regulatory deliverables.
• Proficiency in R programming is a must.
• Demonstrated experience with CDISC standards and regulatory requirements.
• Proven ability to independently lead complex programming efforts across studies.
• Experience mentoring staff and driving technical standards or best practices.
• Demonstrated ability to independently coordinate biostatistical projects, including planning and oversight of programming activities, with minimal direction from senior leadership.

TRAVEL REQUIREMENTS:

0% – 5%

5% - 10%

10% - 20%

20% - 50%

>50%

Pay Range

USD $131,100.00 - USD $160,000.00 /Yr.

EEOC Statement

WCG is proud to be an equal opportunity employer – Qualified applicants will receive consideration for employment based on merit and without regard to race, color, national origin or ancestry, religion or creed, sex, sexual orientation, gender expression, gender identity, age, marital status, family or parental status, disability, genetic information, citizenship, veteran status, or any other legally recognized basis or status protected by federal, state, or local law. WCG complies with the Vietnam Era Veterans' Readjustment Act and Section 503 of the Rehabilitation Act. We promote a "One WCG" culture where all are welcome, respected, valued, and empowered to make a difference every day to advance clinical research.

Location US-Remote

ID 2184

Position Type Regular Full Time

Location Type Remote