Senior Principal Scientist, Clinical Bioanalysis

Scholar Rock, Inc.; Cambridge (MA); On-site; USD 175,000 - 225,000; Full time

Job summary

Scholar Rock, Inc. seeks an accomplished leader in clinical bioanalysis to join the Bioanalytical Sciences team as Principal Scientist, Bioanalytical Specialist.

You will provide scientific and operational leadership across our clinical programs, representing the bioanalytical team at clinical study meetings and guiding CROs in validation, analysis, data delivery, and inspection readiness. The role partners with Discovery, Biomarker Development, Clinical Pharmacology, and Regulatory to align

Qualifications

• PhD in a relevant field with 7+ years of industry experience.
• Experience supporting biologics or complex modalities.
• Oversight of CROs, external labs, or vendors.
• Ability to manage multiple priorities in a fast-paced, collaborative environment.
• Passion for rare disease research and translating science into patient benefit.

Responsibilities

• Provide scientific and strategic leadership for clinical-stage bioanalytical assays (PK, PD, biomarkers, immunogenicity).
• Serve as SME for assay validation, study conduct, sample analysis, data interpretation and regulatory compliance.
• Lead integrated bioanalytical strategies from Phase 1 to Phase 3 clinical programs.
• Oversee outsourced bioanalysis at CROs and partner labs, including transfer, validation, and data delivery.
• Support vendor selection, contracting, start-up, performance monitoring, and risk mitigation.

Education

PhD in biochemistry, immunology, pharmaceutical sciences, or related discipline

Job description

Scholar Rock, Inc. seeks an accomplished leader in clinical bioanalysis to join the Bioanalytical Sciences team as Principal Scientist, Bioanalytical Specialist.

You will provide scientific and operational leadership across our clinical programs, representing the bioanalytical team at clinical study meetings and guiding CROs in validation, analysis, data delivery, and inspection readiness. The role partners with Discovery, Biomarker Development, Clinical Pharmacology, and Regulatory to align