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The American Cancer Society, Inc. is seeking a Senior Principal, Principal Gifts to lead fundraising for gifts of 5M+ and above. The role partners with ACS leadership, volunteers, and staff to craft personalized donor strategies and drive transformational philanthropy.
Remote role across the United States, requiring extensive experience in principal giving, portfolio management, and high-level donor engagement with ultra‑high-net-worth individuals. Travel and executive collaboration are expected.
At the American Cancer Society, we're working to end cancer as we know it, for everyone. Our employees and 1.3 million volunteers are raising the bar every single day. We are a culture comprised of diverse backgrounds and experience, to better serve our communities. The people who work at the American Cancer Society focus their diverse talents on our lifesaving mission. It is a calling. And the people who answer it are fulfilled.
The Senior Principal, Principal Gifts serves as a senior fundraiser with a focus on securing gifts at the $5M+ level.
This position aligns organizational strengths and donor passions in ways that ignite transformational philanthropy, helping donors achieve their philanthropic goals while advancing the ACS vision to end cancer as we know it, for everyone. Designed to be entrepreneurial and collaborative, this role works with leadership, volunteers, and staff across the organization to create and implement personalized donor strategies that lead to long‑term partnerships and deep impact investment. Senior Principals engage with ACS Inc. and ACS CAN board members, members of the ACS Executive Team and other ACS mission staff and are expected to work with these high‑level stakeholders to identify new macro‑level prospects, deepen donor engagement and facilitate successful macro‑level solicitations. In addition, Senior Principals work with assigned department leaders to develop, expand, and refine cases for support, supporting materials and strategy documents for use by the Principal and Foundation Relations Teams, as well as by other fundraisers in the field. Finally, all Senior Principals are expected to understand and execute upon all phases of the ACS All in Against Cancer Campaign and special initiatives as requested by the CEO, CDO and other ACS senior leaders.
This is a Remote role based anywhere in the United States
Travel, including evening and weekend work required
Work setting is in typical office and/or home-based office.
The starting rate is $190,000 to $225,000. The final candidate's relevant experience/skills will be considered before an offer is extended. Actual starting pay will vary based on non-discriminatory factors including, but not limited to, geographic location, experience, skills, specialty, and education.
Further details on our benefits can be found on our careers site at: jobs.cancer.org/benefits.
We are a proud equal opportunity employer. At the American Cancer Society, our employees are the soul of our lifesaving mission to save lives. Our employment opportunities are as diverse as our people and include every discipline found in other business enterprises. As an organization, we adhere to a set of core values that help inform all our decisions. But what really sets us apart is that the work we do has global impact -- and every passionate, dedicated American Cancer Society team member contributes to each groundbreaking achievement we make.