Senior / Principal Medical Science Liaison (MSL)

Zevra Therapeutics, Inc.; Charlotte (NC); On-site; USD 120,000 - 180,000; Full time

Job summary

Zevra Therapeutics, Inc. is seeking a Senior/Principal Medical Science Liaison to join our U.S. Medical Affairs team in the Southeast/Southwest region. The role focuses on scientific exchange, KOL engagement, and evidence generation for rare diseases with our portfolio.

The successful candidate will translate complex clinical data into meaningful dialogue, build long-term collaborations, and travel regularly to meet with stakeholders while ensuring compliance and scientific integrity.

Qualifications

• 5+ years of Medical Science Liaison or related field-based Medical Affairs experience.
• Rare disease experience required; genetics a plus.
• Ability to travel 60–75% and operate in a matrixed organization.

Responsibilities

• Serve as a trusted scientific resource to KOLs, HCPs, researchers, and stakeholders.
• Develop relationships and provide balanced, evidence-based medical information.
• Support medical strategy and publication initiatives.
• Represent Zevra at scientific meetings and advisory boards.
• Collaborate cross-functionally with Clinical Development and Commercial teams.

Skills

Medical affairs

Scientific communication

Relationship building

Travel readiness

Education

MD/PhD/PharmD or equivalent

Tools

Veeva CRM

Job description

Senior / Principal Medical Science Liaison (MSL)

Zevra Therapeutics, Inc. Charlotte, North Carolina, United States

About this position

About Zevra Therapeutics, Inc.
We are a rare disease therapeutics company leading with science to make life-changing therapeutics available to patients with significant unmet needs. We involve key thought leaders, physicians, patients, care partners, and advocacy groups in all of our clinical and regulatory development strategies.
With a keen understanding that drug development often requires creative solutions, we have the insight and expertise to forge new pathways to success that others have missed. By following the data without bias, our transparent narratives and common-sense perspective have successfully overcome complex development challenges to make much-needed therapies available to patients.
Nimble and dauntless, we push boundaries beyond what is thought to be possible and advance new therapies that have the potential to bring meaningful improvement to patients’ lives.

About the role

Zevra Therapeutics is seeking a Senior Medical Science Liaison (Senior MSL) or Principal Medical Science Liaison (Principal MSL) to join our U.S. Medical Affairs organization and support the Southern U.S. territory.

The Senior/Principal MSL will serve as a field-based scientific and clinical expert, developing trusted relationships with healthcare professionals (HCPs), key opinion leaders (KOLs), researchers, and other healthcare decision-makers. Through high-quality scientific exchange and collaboration, this role will advance understanding of rare diseases and Zevra's therapeutic portfolio, support evidence generation and clinical initiatives, and provide meaningful insights that help inform medical and clinical strategy.

The successful candidate will bring deep scientific expertise, strong business acumen, intellectual curiosity, and the ability to translate complex clinical information into meaningful scientific dialogue. They will maintain comprehensive knowledge of relevant disease states, Zevra's therapeutic portfolio, emerging science, the competitive landscape, and applicable regulatory and compliance requirements while ensuring all scientific exchange is accurate, balanced, and evidence-based.

This role is well suited for an experienced field-based Medical Affairs professional who is passionate about rare diseases, enjoys building meaningful relationships within the medical and scientific community, and thrives in a collaborative, growing organization focused on improving outcomes for patients with significant unmet needs.

Territory: S outheast/Southwest U.S. (FL, TX, GA, TN, LA, AL, MS, AR, NC, SC, CO, PR)

What you'll do

• Serve as a trusted scientific and clinical resource to KOLs, HCPs, researchers, and other healthcare stakeholders across the Southern U.S. territory.
• Provide scientific and strategic leadership within the field Medical Affairs organization, sharing best practices and contributing to the continuous improvement of field medical strategy and initiatives.
• Develop and maintain strategic, long-term relationships with external experts and institutions to support meaningful scientific exchange and collaboration.
• Conduct peer-to-peer scientific discussions and provide accurate, balanced, evidence-based medical and scientific information regarding relevant disease states and Zevra's therapeutic portfolio.
• Maintain comprehensive knowledge of relevant disease states, treatment landscapes, clinical data, emerging research, and competitor activity.
• Stay current on scientific and clinical developments within Zevra's areas of interest and communicate relevant developments and insights across the Medical Affairs organization.
• Identify, capture, and communicate meaningful medical insights from the field to help inform medical, clinical, and broader organizational strategies.
• Document HCP interactions and medical insights accurately and consistently within Veeva CRM.
• Support Medical Affairs projects and field-based initiatives aligned with U.S. Medical strategy, objectives, and tactical plans.
• Engage HCPs and potential investigators in scientific discussions related to research opportunities, evidence generation, and clinical trial participation, as appropriate.
• Represent Zevra at scientific congresses, medical meetings, advisory boards, and other relevant external engagements.
• Partner cross-functionally with Medical Affairs, Clinical Development, Commercial, Market Access, and other internal stakeholders while maintaining appropriate Medical Affairs independence and compliance standards.
• Provide scientific education to internal stakeholders on disease states, clinical data, product science, treatment landscapes, and relevant therapeutic guidelines.
• Contribute to scientific communication initiatives, including publication planning, medical information resources, and other educational materials, as appropriate.

Qualifications

• MD, PhD, PharmD, DNP, or equivalent advanced scientific or clinical degree preferred.
• 5+ years of Medical Science Liaison or related field-based Medical Affairs experience within the pharmaceutical or biotechnology industry.
• Rare disease experience required, with experience in lysosomal, metabolic, or rare neurological disorders preferred.
• Experience in genetics or genetically driven diseases is a plus.
• Demonstrated ability to establish credibility and develop strategic, long-term relationships with KOLs, HCPs, researchers, and other scientific stakeholders.
• Strong scientific communication and presentation skills, with the ability to communicate complex clinical and scientific information effectively to diverse audiences.
• Strong business acumen and understanding of the regulatory and compliance requirements governing field-based Medical Affairs activities.
• Ability to work independently in a field-based environment while collaborating effectively across a matrixed organization.
• Strong organizational skills and demonstrated ability to effectively manage a geographically dispersed territory.
• Must reside within the assigned territory (FL, TX, GA, TN, LA, AL, MS, AR, NC, SC, CO, or PR).
• Ability to travel approximately 60–75%, including overnight travel and occasional weekends, based on business needs.
• Valid driver's license and ability to operate a company-provided vehicle.

Equal Employment Opportunity Statement

Zevra is an equal opportunity employer that is committed to diversity and inclusion in the workplace. We prohibit discrimination and harassment of any kind based on race, color, sex, religion, sexual orientation, national origin, disability, genetic information, pregnancy, or any other protected characteristic as outlined by federal, state, or local laws.