Senior Principal Computational Chemist – Structure-Based Drug Design

Initial Therapeutics, Inc.; South San Francisco (CA); Hybrid; USD 196,000 - 242,000; Full time

Benefits offered by this job

Medical/dental/vision coverage

401(k)

ESPP

Wellness programs

Job summary

IDEAYA Biosciences in South San Francisco is seeking a Senior Principal Research Scientist in Computational Chemistry. This senior individual-contributor role demands significant pharmaceutical industry experience, focusing on advancing drug discovery programs. Responsibilities include leading drug design meetings, supporting project teams, and mentoring other scientists. The expected salary range is $196,000 – $242,000, with a comprehensive benefits package including medical coverage and 401(k).

Qualifications

• 9+ years of pharmaceutical or biotechnology industry experience.
• Proven ability to independently deliver computational work that influences decisions.
• Excellent oral and written communication skills.

Responsibilities

• Lead structure-based drug design meetings with medicinal chemists.
• Contribute to programs from target identification through lead optimization.
• Mentor and coach other scientists in structure-based drug design.

Skills

Computational Chemistry

Drug Discovery

Medicinal Chemistry

Molecular Dynamics

Cheminformatics

Education

PhD in Computational Chemistry or related discipline

Tools

Schrödinger modeling software

MOE

OpenEye

Job description

IDEAYA Biosciences in South San Francisco is seeking a Senior Principal Research Scientist in Computational Chemistry. This senior individual-contributor role demands significant pharmaceutical industry experience, focusing on advancing drug discovery programs. Responsibilities include leading drug design meetings, supporting project teams, and mentoring other scientists. The expected salary range is $196,000 – $242,000, with a comprehensive benefits package including medical coverage and 401(k).