Senior Principal, Biostatistical Programming

Scorpion Therapeutics; Wilmington (DE); On-site; USD 120,000 - 180,000; Full time

Job summary

Scorpion Therapeutics seeks a Senior Principal Biostatistical Programmer to lead data processing and analysis for Phase I–III clinical trials in a biopharma setting. You will generate analysis datasets using SAS, ensure CDISC compliance, develop macros, validate outputs, review SAPs and datasets, and mentor team members while collaborating with CROs to support submissions.

Candidates should have strong SAS/Base/Macro skills, CDISC knowledge, several years in biopharma or CRO, and a degree in

Qualifications

• Strong SAS/Base/Macro skills and CDISC knowledge.
• Several years of experience in biopharma or CRO.
• Degree in statistics or computer science or equivalent experience.
• Experience leading projects and mentoring team members.

Responsibilities

• Lead data processing and analysis for Phase I–III trials.
• Generate analysis datasets and ensure CDISC compliance.
• Develop macros and validate outputs.
• Review SAPs and datasets; manage timelines and quality.
• Collaborate with CROs and support regulatory submissions.

Skills

SAS programming

CDISC standards

SAS Base/Macro

Project leadership

Mentoring

CRO collaboration

Education

Statistics or Computer Science degree

Tools

SAS/Base

SAS/Macros

Job description

Role: Senior Principal Biostatistical Programmer leading data processing and analysis for Phase I-III clinical trials in a biopharma setting.

Responsibilities: perform SAS programming to generate analysis datasets, ensure CDISC compliance, develop macros, validate outputs, review SAP and datasets, and oversee programming quality and timelines for studies; act as project lead and mentor to team members, collaborate with CROs, and support submission activities.

Requirements: strong SAS/Base/Macro skills, knowledge of CDISC standards, several years of experience in biopharma or CRO, degree in statistics/computer science or equivalent experience, and project leadership abilities.

Preferred: experience with regulatory submission standards and data management.

High-Value: focus on clinical data analysis for hematology, oncology, or inflammatory autoimmune indications; involvement in Phase I-III trials; emphasis on GxP, regulatory compliance, CDISC, and cross-functional teamwork.

Work setup: not specified; requires effective multitasking and leadership in a dynamic environment.