Senior Principal AI/ML Engineer - Frontend Engineering
Mayo Foundation for Medical Education and Research
Get a reply from this employer — a resume and cover letter tailored to exactly what they’re hiring for.
Benefits offered by this job
Job summary
Mayo Clinic seeks a Senior Principal AI/ML Engineer to lead the full AI lifecycle from ideation to production. You will work with clinicians, UX designers, product managers, and IT professionals to build and deploy innovative AI solutions that improve patient care and clinical workflows.
Applicants should have extensive experience in AI/ML techniques, healthcare data, and cloud environments, plus a track record of mentoring and delivering complex, regulated projects.
Qualifications
- MASTER’S DEGREE or higher in engineering, computer science, health science, or related field; 9+ years of experience
- Bachelor’s degree with 11 years of relevant experience, or equivalent
- Extensive experience applying AI/ML in healthcare or regulated industries
- Proven leadership in managing complex AI/ML projects
- Strong collaboration and communication with non-technical stakeholders
Responsibilities
- Lead the end-to-end AI/ML life cycle from ideation to production
- Collaborate with clinicians, designers, PMs, and IT staff to translate needs into AI solutions
- Develop, integrate, and standardize software components for healthcare AI
- Oversee CI/CD tooling and automated release processes
- Provide mentorship and technical direction to engineers and teams
- Ensure compliance with regulatory, privacy, and ethical guidelines
Skills
Education
Tools
Job description
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans– to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
- Medical:Multiple plan options.
- Dental:Delta Dental or reimbursement account for flexible coverage.
- Vision:Affordable plan with national network.
- Pre-Tax Savings:HSA and FSAs for eligible expenses.
- Retirement: Competitive retirement package to secure your future.
AI/ML Engineers at Mayo Clinic play a pivotal role in the union of data, systems, and computer sciences. They work closely with a multidisciplinary team, including clinicians, user experience designers, product managers, IT professionals, and external partners, to develop and deploy effective, efficient, and ethical AI/ML solutions into clinical practice to enhance patient care and operational efficiency. As a Senior Principal AI/ML Engineer, you will lead the full spectrum of the AI life cycle from ideation to production. You understand the clinical environment well, including workflows, challenges, and requirements of healthcare providers and patients. You will leverage advanced techniques in AI/ML to analyze vast amounts of healthcare data, including patient records, medical imaging, and genomic information, to develop AI solutions that meet clinical needs and are integrated smoothly into clinical processes. You will develop, integrate, and standardize software components and create, maintain, and follow quality system procedures. You will guide the engineering of systems that are pivotal to developing and deploying these solutions, which encompass everything from design requirements, development, component creation, verification, non-clinical validation, and risk mitigation to ensure our digital health technology products meet and exceed regulatory requirements and setting new benchmarks for safety and effectiveness in clinical settings. Your expertise will also extend to facilitating consistent and automated AI software solution development and releases through the design, testing, and maintenance of tools and associated CI/CD pipelines. This role is instrumental in leading consultative services to departments and divisions, offering insights into complex business problems. Your ability to communicate complex findings in easily understandable terms to non-technical users will bridge the gap between sophisticated AI technologies and clinical applications. Senior Principal AI/ML Engineers are recognized as top technical authorities in the field of AI/ML and play a critical role in driving innovation and shaping the strategic direction of AI/ML initiatives at Mayo Clinic.
Other Responsibilities May Include:
- Providing strategic direction and technical leadership for AI Engineering initiatives.
- Working with leadership team to define the AI roadmap and prioritize projects aligned with organizational objectives.
- Leading component design, development, integration, and standardization to create AI-driven solutions that seamlessly integrate into clinical practice to enhance patient care and clinic operations.
- Leading the collaboration with multidisciplinary teams, including clinicians, user experience designers, product managers, and IT professionals, to understand user needs, workflows, and clinical requirements and assess feasibility. Translating user feedback and requirements into design concepts and usability specifications for AI solutions.
- Leading the interpretation of data analysis to guide strategic choices and clarify complex insights for non-technical users to connect AI technologies and clinical applications.
- Leading consultative services to clinical work units or AI product teams, offering insights and strategies to address complex business problems.
- Leveraging machine learning techniques such as deep learning, natural language processing, computer vision, large language models, etc., to lead the design, development, and deployment of end-to-end AI solutions for healthcare applications.
- Establish rigorous evaluation methodologies and performance metrics to assess the effectiveness, usability, and impact of AI solutions in real-world healthcare settings.
- Ensuring compliance with ethical guidelines, regulatory requirements, and data privacy standards in the development and deployment of AI solutions by the AI development team.
- Overseeing the engineering of systems crucial for developing and deploying AI solutions.
- Owning the design and the quality of the frontend engineering domain end to end, and mentoring the engineers who work in it. The architect decides how the domains fit together; this role decides how this domain works inside
- Facilitating consistent and automated AI software solution development and releases through the design, testing, and maintenance of tools and associated CI/CD pipelines.
- Defining and implementing best practices and standards for AI development and deployment methodologies, tools, and platforms.
- Providing mentorship, guidance, and technical leadership to junior engineers within the AI enablement team. May have supervisory responsibilities.
- Fostering a culture of collaboration, innovation, and knowledge sharing across the organization.
- Supporting talent development initiatives, including training programs, technical workshops, and skill-building activities to enhance team capabilities.
- Contributing to the development of new AI methods and technologies that can advance the state-of-the-art in healthcare AI.
- Publishing and presenting the results of AI development and translation in peer-reviewed journals and conferences.
This vacancy is not eligible for sponsorship/ we will not sponsor or transfer visas for this position. Also, Mayo Clinic DOES NOT participate in the F-1 STEM OPT extension program.
- A master’s degree in engineering, computer science, mathematics, health science, or a related field with 9 years of relevant experience, or a bachelor’s degree with 11 years of relevant experience.
- Extensive (9+ years) experience applying AI and machine learning in production healthcare environments or similar highly regulated or technology focused industries, showcasing an acute understanding of healthcare technology.
- Demonstrated leadership in managing complex projects, with a proven ability to navigate intricate project requirements and deliver successful outcomes.
- Proven success in fostering collaboration across diverse teams and effectively communicating complex technical concepts to non-technical stakeholders.
- Demonstrated expertise in cloud infrastructure environment and software development tools.
- Experience working with large, complex, and heterogeneous data sets, preferably in healthcare.
- Strong skills in AI/ML techniques and frameworks.
- Expertise with best practices in data engineering, data science, AI Engineering, and the MLOps communities.
- In-depth knowledge of healthcare domain, including clinical workflows, electronic health records, medical terminologies, regulatory requirements, and industry standards.
- Demonstrated leadership in administration, education, software development, and technical reporting.
- Experience mentoring and training less-experienced team members, coupled with strong interpersonal, communication, and time management skills.
Preferred qualifications:
- A Ph.D. or other doctorate degree is preferred.
- Strong expertise in AI/ML techniques and frameworks, such as deep learning, natural language processing, and Generative AI, with proficiency in tools like Python, TensorFlow, PyTorch, sci-kit-learn, Keras, etc.
- Deep experience building and maintaining production frontends, including component architecture, state management, performance and accessibility
- Experience with healthcare industry informatics standards, best practices, and common data models. Participation in national or international standards organizations or other domain-specific professional organizations, or extensive implementation experience with common data, development, and deployment standards.
- Excellent communication, collaboration, and stakeholder management skills, with the ability to effectively engage with diverse stakeholders and translate complex technical concepts and results to non-technical audiences.
- Demonstrated experience leading technical/quantitative teams in a regulated environment.
- Familiarity with systems or quality engineering best practices, regulatory standards, and compliance frameworks, with the ability to adapt these effectively to different project scenarios.
- Demonstrated experience creating risk management files and verification/validation strategies for digital health technology products within the healthcare industry.
- Demonstrated expertise in user-centered design, human factors engineering, usability testing methodologies, and evaluation across AI product development. Ability to lead expert reviews using established usability practices and methods. Presents findings in easy-to-understand terms for the business or clinical practice.
- Strong problem-solving abilities, critical thinking skills, and a passion for driving innovation and positive change in healthcare through AI technology.
Exempt
$180,024.00 - $261,019.20/ year. Education, experience and tenure may be considered along with internal equity when job offers are extended.
Yes
Full Time
80
M-F 8am-5pm This is a hybrid position and must be located within 100 miles of a Mayo Clinic campus for occasional on-site expectations based on business needs.
NA
No
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the'EOE is the Law'. Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.
Recruiter Laura Percival
'/%3e%3cpath%20d='M101.744%2012.4726L102.894%2016.1947L99.0021%2013.2201L101.744%2012.4726ZM105.3%208.40937H100.488L99.0026%203.59473L97.5116%208.41047L92.7%208.40385L96.5965%2011.3834L95.1055%2016.1942L99.0021%2013.2196L101.408%2011.3834L105.3%208.40992V8.40937Z'%20fill='white'/%3e%3cdefs%3e%3clinearGradient%20id='paint0_linear_5593_1381'%20x1='90'%20y1='9.44471'%20x2='99'%20y2='9.44471'%20gradientUnits='userSpaceOnUse'%3e%3cstop%20stop-color='%2300AD70'/%3e%3cstop%20offset='0.998594'%20stop-color='%2300B67A'/%3e%3cstop%20offset='1'%20stop-color='%23DCDCE6'/%3e%3c/linearGradient%3e%3c/defs%3e%3c/svg%3e){kind=small}
