Senior Oral Solid Dose Scientist: Formulation & Scale-Up

SRG; Richmond (VA); Sur place; USD 120 000 - 180 000; Plein temps

Résumé du poste

Impellam Group is seeking a Senior Development Scientist for our Oral Solid Dose (OSD) development program in Richmond, VA. The role leads formulation design, rigorous experimentation, and scale-up from lab to manufacturing with a focus on QbD and robust processes.

You will drive DoE studies, material characterization, and cross-functional collaboration to meet quality, performance, and regulatory standards. Advanced degree preferred; 5+ years of relevant experience strongly valued.

Qualifications

• Bachelor's degree in Pharmacy or Life Sciences required.
• 5+ years of relevant experience.
• Master's or PhD preferred.
• Knowledge of regulatory requirements and drug development.

Responsabilités

• Lead formulation design and development using QbD and material science.
• Develop prototypes, optimize formulations, and establish a Design Space through DoE.
• Evaluate API-excipient interactions and process parameters for robust formulations.
• Develop Direct Compression, wet/dry granulation, and continuous manufacturing formulations.
• Plan, execute, and interpret DoE to understand material attributes and process parameters.
• Apply root cause analysis to resolve formulation and process failures.
• Characterize raw materials and blends (PSD, microscopy, rheology, moisture, compressibility).
• Design scalable manufacturing processes and transfer knowledge to site teams.
• Prepare technical protocols, reports, and CMC Module 3 regulatory documentation.
• Collaborate with Analytical, Quality, and Regulatory teams; present findings internally and externally.
• Communicate conclusions and next steps to matrix leaders.

Connaissances

Formulation design

DoE

Scale-up

Material characterization

Quality by Design

Regulatory compliance

Root cause analysis

Data analysis

Process understanding

Cross-functional collaboration

Formation

Bachelor's degree in Pharmacy or Life Sciences

Master's, PhD or equivalent

Description du poste

Impellam Group is seeking a Senior Development Scientist for our Oral Solid Dose (OSD) development program in Richmond, VA. The role leads formulation design, rigorous experimentation, and scale-up from lab to manufacturing with a focus on QbD and robust processes.

You will drive DoE studies, material characterization, and cross-functional collaboration to meet quality, performance, and regulatory standards. Advanced degree preferred; 5+ years of relevant experience strongly valued.