Senior MES Engineer

Startup Talents; Cary (NC); On-site; USD 110,000 - 120,000; Full time

Benefits offered by this job

ESOP participation

Job summary

Startup Talents招聘一名资深 MES 工程师，工作地点在北卡罗来纳州的Raleigh，现场职位。候选人将领导MES方案的评估、设计、实施、测试、投产，协调跨职能团队并确保遵守cGMP与21 CFR Part 11等要求。

该职位需熟悉 Werum PAS-X、Sepasoft、POMS 等平台，具备IT/OT网络、数据库和ERP接口经验，且愿意在客户现场长期工作与出差。公司提供 ESOP 与成长机会。

Qualifications

• Proven experience with all phases of MES projects in Life Science.
• Knowledge of regulatory requirements such as cGMP and 21 CFR Part 11 is preferred.
• Experience designing and implementing MES recipes using standards (GAMP5, S88, S95) is desirable.

Responsibilities

• Lead MES projects and act as solution architect on industrial processes.
• Guide engineers and technicians; may perform Project Manager duties on smaller projects.
• Develop MES strategies integrating process knowledge, equipment, and IT to improve compliance and efficiency.
• Ensure project profitability and timely delivery within budget.

Skills

MES experience

Leadership

Regulatory knowledge

SQL/Oracle

IT/OT networking

Project management

Education

Bachelor's degree in Engineering

Tools

Werum PAS-X

Sepasoft

POMS

DeltaV

SAP

LIMS

PI

Maximo

Job description

Cary, United States | Posted on 03/01/2026

An engineering firm specializing in process controls solutions and experts in the design, programming and deployment of automation systems for process, manufacturing, commercial buildings and public sector utilitiesis opening a Senior MES Engineer position in Raleigh, North Carolina (USA)

This is a great opportunity to join a 100% employee-owned ESOP and one of the largest and most well-established engineering companies in the United States skilled at electrical design, control system manufacturing, process integration, programming, testing, training, and ongoing support.

Company Size : 201-500

Education :A Bachelor of Science degree in Engineering, Computer Science or the Applied Sciences required.

Experience :

Proven experience with all phases of MES projects including conceptual, basis of design, implementation, testing, start-up, and commissioning in the Life Science industry

Familiarity with relevant regulatory requirements of the life science industry such as cGMP, 21 CFR Part 11, etc.

Demonstrated proficiency with designing and implementing integrated EBR recipes using GAMP5, S88, and S95 standards

Preferred certifications and credentials :

Greater than 10 years with capabilities in the below areas is preferred :MES solution deployment experience with but not limited to Werum PAS-X, Sepasoft, or POMS

Required tools/systems/processes mastery :

Experience – Greater than 10 years with capabilities in the below areas is preferred:

MES solution deployment experience with but not limited to Werum PAS-X, Sepasoft, or POMS

Proven experience with all phases of MES projects including conceptual, basis of design, implementation, testing, start-up, and commissioning in the Life Science industry

Familiarity with life science industry regulatory requirements such as cGMP, 21 CFR Part 11, etc.

Proficiency with designing and implementing integrated EBR recipes using GAMP5, S88, and S95 standards

Support software and configuration required for external systems interfaces such as DeltaV, SAP, LIMS, PI, and Maximo

Strong knowledge of historian technology and reporting systems

Experience with relational databases such as SQL, Oracle, etc.

Strong knowledge of IT/OT networking

Work Model: 100% onsite at client/project locations. Must live within reasonable commuting distance or be willing to relocate to Raleigh with limited relocation assistance available.

Travel : Ability to travel up to 30% worst case (10% is typical with last couple years depending on project)

Physical Demands of Position : Seeing, color perception, hearing, listening, clear speech, dexterity in hands, driving, lifting, climbing, ability to mount and dismount equipment, pushing, and pulling

Working Condition : Expected on client location 5 days a week, Standard office environment, On-site office environment, and diverse industrial/construction environments. Frequent PC usage, copy machines, phones.

Shift patterns : Capable of working \"off\" shifts as needed during installation/commissioning to support project

Relocation Assistance : Limited assistance

Visa sponsorship eligibility : Not included

This position requires demonstrated technical proficiency in software design and configuration of MES solutions with integration capabilities to level two and four systems.

As a Senior MES Engineer you will interact directly with the customer and lead a team of engineers in identifying requirements, evaluating MES platforms, developing specifications, and implementing/testing/commissioning/qualifying MES solutions. You also demonstate success by securing repeat work with both new and existing customers.

It is a leadership role within the business unit and requires strong problem-solving ability, well-balanced people skills, an aptitude for business efficiency, and an interest in creating partnerships.

Missions

• Responsible fordelivering innovative MES solutions and design standards either self-directedly or as a leader of a team.


• Act as a solution architect with the ability to conceptualize, detail, and implement MES Solutions for industrial processes and machinery that meet customers' requirements.


• Act as technical lead on projects and guide lower-level engineers and technicians + as Project Manager on smaller projects.


• This involves the development of an MES strategy that integrates process knowledge, equipment design, and quality standards with information technology to reduce downtime, elevate the level of regulatory compliance, and introduce efficiency gains through the effective use of available technologies.


• Project management responsibilities:Developing project execution plans, work breakdown structures, and associated budgets, task prioritization and scheduling, task ordering, time tracking, and reporting, financial tracking and reporting, early problem identification, conflict management/resolution, leading and supporting a team, and attending project status meetings. Also includes overseeing daily operations and activities of a project(s) up to $1M.


• Responsible for ensuring the overall profitability of the project.

Requirements

Ideally have a diverse engineering skillset with the ability to work independently.

Coordination experience with multiple systems from controls to ERP (PLC/DCS; Historian technology; reporting systems; relational databases; ERP's)

Understand the manufacturing processes and system configuration and make informed recommendations regarding optimal system configuration

Understanding of warehouse and inventory management specifically in a GMP facility

Support software and configuration required for external systems interfaces such as DeltaV, SAP, LIMS, PI, and Maximo

Strong knowledge of historian technology and reporting systems

Experience with relational databases such as SQL, Oracle, etc.

Strong knowledge of IT/OT networking

Excellent technical writing and verbal communication skills

Working knowledge of MS Office products

Experience leading a team of engineers/technicians to provide MES solutions

Experience mentoring less experienced engineers

Professional references, preferably one from each of the following: a subordinate, a peer, and a manager

Ability to travel up to 25%

Conditions :

Permanent role

Salary :$110K-$120K base plus annual bonus and ESOP participation