Senior Medical Science Liaison, Central (Multiple Territories)

Praxis Precision Medicines, Inc.; Oregon; Hybrid; USD 190,000 - 220,000; Full time

Benefits offered by this job

Company-paid medical/dental/vision

401(k) with company match up to 6%

Stock incentives & ESPP

Discretionary quarterly bonus

Flexible wellness benefit

Generous PTO and holidays

Job summary

Praxis Precision Medicines, Inc. is seeking a field-based Senior Medical Science Liaison to support prelaunch and launch activities. The role emphasizes translating clinical data into meaningful insights for the field, educating healthcare professionals, and driving field strategy in a fast-paced launch environment.

You will work cross-functionally with Medical, Clinical Development, Market Access, and Commercial teams to align on and execute field strategy, while traveling extensively (60–80%).

Qualifications

• Advanced clinical or scientific degree required.
• Ability to interpret and convey complex data clearly to diverse audiences.
• Strong ownership mindset and independence in field settings.

Responsibilities

• Serve as field-based scientific partner to investigators and stakeholders.
• Deliver scientific exchanges on disease state and clinical data for the ulcerative product profile.
• Educate clinical sites and providers for launch and readiness.
• Gather and synthesize field insights to inform strategy across teams.
• Identify and engage key opinion leaders and influencers for engagement strategies.
• Collaborate with Medical, Clinical Development, Market Access, and Commercial teams.
• Represent Praxis at scientific congresses and advisory engagements.
• Maintain CNS/neurology expertise to inform field strategy.
• Ensure field activities comply with regulatory and Praxis policies.

Skills

Scientific communication

KOL engagement

Field-based flexibility

Cross-functional collaboration

Travel readiness

Education

Advanced clinical or scientific degree (PharmD, PhD, MD, NP, PA, or RN)

Job description

Location

This position may be performed remotely with the required ability to travel up to 60–80%, as needed. Locations: Omaha, NE; Ann Arbor, MI; Grand Rapids, MI; Columbus, OH; Chicago, IL; Indianapolis, IN.

Position Summary

Praxis is seeking a field-based Senior Medical Science Liaisons (MSL) to support prelaunch and launch activities. This role will focus on building trusted relationships with investigators and key stakeholders, delivering high-quality scientific exchange, and ensuring clinical and account readiness in advance of and following potential approval. You will play a critical role in translating clinical data into meaningful insights for the field, educating healthcare professionals on disease state and emerging data, and identifying opportunities and barriers that may impact adoption. Working cross‑functionally with Medical, Clinical Development, and Commercial teams, you will help shape and execute field strategy in a dynamic, fast‑moving launch environment. This is not a passive, reactive role – you are expected to operate with a high degree of ownership, proactively generate insights, and influence the field through credible, science‑driven engagement. We are open to hiring across levels and seek individuals who can operate independently in the field – whether developing into the role or already leading at a high level. Leveling will reflect experience, judgment, and the ability to drive impact in a prelaunch/launch setting. Success in this role requires strong clinical credibility, excellent communication skills, strategic thinking, and comfort operating autonomously in a fast‑paced environment.

Primary Responsibilities

• Serve as the primary field‑based scientific partner to investigators and key stakeholders, building trusted relationships to support prelaunch readiness and successful product adoption.
• Deliver high‑quality scientific exchange on disease state, clinical data, and the ulixacaltimide profile, ensuring clear understanding of its potential role in treatment.
• Educate and prepare clinical sites and healthcare providers for launch, including patient identification, treatment considerations, and integration into clinical practice.
• Proactively gather, synthesize, and communicate field insights (e.g., treatment paradigms, barriers to adoption, unmet needs) to inform medical and cross‑functional strategy.
• Identify and engage key opinion leaders (KOLs) and emerging influencers, supporting the development of advocacy and scientific engagement strategies.
• Partner cross‑functionally with Medical, Clinical Development, Market Access, and Commercial teams to align on and execute field strategy.
• Represent Praxis at scientific congresses and advisory engagements, translating external insights into actionable recommendations.
• Maintain deep expertise in CNS/neurology, including evolving treatment landscapes and competitive developments, and apply insights to field strategy.
• Ensure all field activities are conducted in compliance with regulatory requirements, GCP standards (as applicable), and Praxis policies and SOPs.

Qualifications and Key Success Factors

• Advanced clinical or scientific degree (PharmD, PhD, MD, NP, PA, or RN)
• Experience in medical affairs, clinical research, clinical care, or field‑based roles within biotech/pharma
• Demonstrated ability to interpret and communicate complex scientific and clinical data with clarity and credibility to diverse stakeholders
• Strong ownership mindset with the ability to operate independently, navigate ambiguity, and drive impact in a dynamic, prelaunch/launch environment
• Proven ability to build and maintain trusted relationships with healthcare professionals, including investigators and key opinion leaders
• Experience gathering and translating field insights into actionable recommendations for cross‑functional teams
• Ability to manage multiple priorities with strong organizational skills, attention to detail, and consistent follow‑through
• Willingness and ability to travel extensively (~60–80%) in a field‑based role
• Experience in neurology or CNS disorders preferred
• Experience within market access/payor landscape preferred
• Candidates with prior field‑based experience and a demonstrated track record of independently driving scientific engagement, shaping clinical perspectives, and contributing to successful pre‑launch and launch activities will be considered at a higher level

Annualized Base Salary

$190,000—$220,000 USD

Compensation & Benefits

• 99% of the premium paid for medical, dental and vision plans.
• Company‑paid life insurance, AD&D, disability benefits, and voluntary plans to personalize coverage.
• Dollar‑for‑dollar matching up to 6% on eligible 401(k) contributions.
• Long‑term stock incentives and ESPP.
• Discretionary quarterly bonus.
• Extremely flexible wellness benefit.
• Generous PTO, paid holidays and company‑wide shutdowns.

Company Overview

Praxis Precision Medicines is a clinical‑stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance. At Praxis we share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high‑impact medicines for patients and families affected by and living with complex brain disorders.

Core Values

Trust, Ownership, Curiosity and Results are foundational to every aspect of our business and are exemplified by each and every one of our team members.

Diversity, Equity & Inclusion

Guided by our core values, at Praxis Precision Medicines, Inc. we continue to DARE FOR MORE® to advance, promote, and champion diversity, equity, and inclusion by encouraging individuals to bring their authentic selves and perspectives to work each day. We are an equal opportunity employer and committed to providing opportunities to all qualified applicants without regard to race, religious creed, color, gender identity or expression, age, national origin, sexual orientation, disability, genetics, military service and veteran status, or any other characteristic protected by federal, state, or local laws.