Senior Medical Director, Clinical Development

Meet Life Sciences Ltd.; Cambridge (MA); On-site; USD 260,000 - 400,000; Full time

Job summary

Meet Life Sciences Ltd. in Cambridge, MA, seeks a Senior Medical Director, Clinical Development to lead global oncology trials with a focus on medical monitoring and patient safety.

The role requires an MD with board eligibility in oncology and 5+ years of clinical development experience, preferably in solid tumors. You will lead cross-functional teams and interact with regulators during trial submissions.

Qualifications

• MD or equivalent medical degree required.
• Board certification or board eligibility in Medical Oncology, Hematology/Oncology, or a related specialty strongly preferred.
• Approximately five or more years of clinical development experience within a biotechnology, pharmaceutical, or related research organization.
• Demonstrated experience serving as a study physician or medical monitor for interventional oncology clinical trials.
• Strong knowledge of solid-tumor drug development and contemporary oncology clinical practice.

Responsibilities

• Serve as the medical lead and study physician for global oncology clinical trials.
• Provide hands-on medical monitoring, including review of eligibility, safety events, lab findings, dose modifications, protocol deviations, and patient-level data.
• Lead ongoing assessment of safety, efficacy, pharmacokinetic, and pharmacodynamic data.
• Collaborate with Clinical Operations, Biostatistics, Data Management, Regulatory Affairs, Pharmacovigilance, Translational Medicine, and Medical Writing.
• Contribute to development plans, study concepts, protocols, informed consent documents, investigator brochures, clinical study reports, and regulatory submissions.
• Support study design, dose-escalation and expansion strategies, and benefit-risk assessments.
• Provide medical guidance to investigators, study sites, CROs, and internal teams.
• Lead or participate in safety review committees, data review meetings, investigator meetings, and governance discussions.
• Develop relationships with investigators and key opinion leaders; support interactions with health authorities including the FDA.
• Evaluate clinical data to identify trends, risks, and optimization opportunities.
• Contribute to publications, abstracts, and presentations.

Skills

Study physician

Oncology clinical trials

Safety monitoring

Data review

Regulatory interactions

Cross-functional collaboration

Global teams

Medical leadership

Education

MD or equivalent medical degree

Board certification in Medical Oncology or Hematology/Oncology

Job description

Senior Medical Director, Clinical Development

Location: Cambridge, Massachusetts

Employment Type: Full-Time

Position Overview

This individual will serve as a senior study physician supporting the development of novel therapies for patients with solid tumors. The Senior Medical Director will provide medical leadership across global clinical trials, with a strong emphasis on hands‑on medical monitoring, patient safety, clinical data review, and cross‑functional study execution. The position is well suited to an oncologist with experience leading early‑ and late‑stage clinical studies who wants to remain closely involved in the scientific and medical aspects of clinical development. Experience in lung cancer, including small‑cell lung cancer, and antibody‑drug conjugates is highly desirable, although candidates with broader solid‑tumor expertise will also be considered.

Responsibilities

• Serve as the medical lead and study physician for global oncology clinical trials.
• Provide hands‑on medical monitoring, including the review of patient eligibility, safety events, laboratory findings, dose modifications, protocol deviations, and patient‑level clinical data.
• Lead the ongoing assessment of emerging safety, efficacy, pharmacokinetic, and pharmacodynamic data.
• Collaborate closely with Clinical Operations, Biostatistics, Data Management, Regulatory Affairs, Pharmacovigilance, Translational Medicine, and Medical Writing.
• Contribute to clinical development plans, study concepts, protocols, informed consent documents, investigator brochures, clinical study reports, and regulatory submissions.
• Support study design, dose‑escalation and expansion strategies, and benefit‑risk assessments.
• Provide medical guidance to investigators, study sites, CROs, and internal clinical study teams.
• Lead or participate in safety review committees, data review meetings, investigator meetings, and program‑governance discussions.
• Develop productive relationships with investigators, key opinion leaders, cooperative groups, and external scientific experts.
• Support interactions with global health authorities, including the FDA and other regulatory agencies.
• Evaluate clinical data to identify meaningful trends, emerging risks, and opportunities to optimize development strategy.
• Contribute to publications, abstracts, scientific presentations, and the communication of clinical study results.
• Provide scientific and medical input into potential indications, combination strategies, and lifecycle‑development opportunities.
• Mentor clinical scientists and other members of the clinical development organization.

Qualifications

• MD or equivalent medical degree required.
• Board certification or board eligibility in Medical Oncology, Hematology/Oncology, or a related specialty strongly preferred.
• Approximately five or more years of clinical development experience within a biotechnology, pharmaceutical, or related research organization.
• Demonstrated experience serving as a study physician or medical monitor for interventional oncology clinical trials.
• Strong knowledge of solid‑tumor drug development and contemporary oncology clinical practice.
• Experience reviewing patient‑level safety and efficacy data and making timely medical decisions.
• Experience contributing to clinical protocols, development plans, regulatory documents, and health‑authority interactions.
• Ability to operate effectively across global, multidisciplinary clinical development teams.
• Strong written, verbal, presentation, and relationship‑management skills.
• Sound clinical judgment and the ability to succeed in a fast‑paced, data‑driven environment.

Required Skills

• Demonstrated experience serving as a study physician or medical monitor for interventional oncology clinical trials.
• Strong knowledge of solid‑tumor drug development and contemporary oncology clinical practice.
• Experience reviewing patient‑level safety and efficacy data and making timely medical decisions.
• Experience contributing to clinical protocols, development plans, regulatory documents, and health‑authority interactions.
• Ability to operate effectively across global, multidisciplinary clinical development teams.
• Strong written, verbal, presentation, and relationship‑management skills.
• Sound clinical judgment and the ability to succeed in a fast‑paced, data‑driven environment.

Preferred Skills

• Clinical or drug‑development experience in lung cancer, particularly small‑cell lung cancer.
• Experience developing antibody‑drug conjugates or other targeted oncology therapies.
• Experience within global Ph3 studies
• Familiarity with global clinical programs conducted across the United States, Europe, and Asia.
• Experience supporting regulatory submissions or major clinical-development milestones.