Senior Manager, Program Management

CSL; King of Prussia (PA); Hybrid; USD 140,000 - 190,000; Full time

Job summary

CSL Behring is seeking a Senior Manager, Program Management in King of Prussia, PA to drive end-to-end medical program management across the portfolio. You will partner with Global and Regional Medical Affairs leadership and cross-functional teams to enable timely, high-quality execution of medical strategy embedded in the portfolio.

You will lead planning, budgeting, governance, and delivery of key medical outputs, including evidence plans, publication planning, and strategic documents,

Qualifications

• Bachelor's degree required.
• 8+ years’ relevant experience in medical affairs operations/program management, cross-functional business operations, or related pharmaceutical/biotech experience.
• Demonstrated ability to lead complex, cross-functional initiatives in a matrix environment, including governance, senior stakeholder management, and influencing without authority.
• Strong strategic thinking, problem-solving, and execution focus with the ability to translate strategy into integrated plans, milestones, and measurable outcomes.
• Proficiency with project/program management tools (e.g., Smartsheet), timeline development (e.g., Gantt charts), and budget management; able to develop fit-for-purpose dashboards and reporting.

Responsibilities

• Lead the Medical Affairs Strategy Team (MAST) operating model for the assigned disease area(s).
• Own integration of Medical Affairs priorities into cross-functional governance forums.
• Drive cross-functional execution of priorities across Medical Affairs and key partners while ensuring SOP/gov compliance.
• Oversee project management and process framework for enterprise-wide initiatives and ensure alignment across functions.
• Manage the annual medical planning process linked to Brand Planning with timely delivery of plans and insights.
• Lead implementation and improvement of global templates, budgets, trackers, and dashboards.
• Develop and maintain the integrated business process calendar for milestones, congress planning, and core medical documents.
• Ensure resource availability and proactive risk mitigation.
• Lead budget planning, tracking, and forecasting for medical affairs activities with Finance.
• Identify and manage cross-functional execution risks and interdependencies.
• Facilitate scenario planning for portfolio-level visibility and decision-making.
• Establish and monitor program-level metrics and dashboards with concise readouts.
• Coach and mentor program management colleagues and share best practices.

Skills

Strategic thinking

Problem-solving

Execution focus

Education

Bachelor's degree

Tools

Smartsheet

Gantt charts

Job description

Senior Manager, Program Management

The Senior Manager, Program Management is accountable for driving integrated execution and visibility of Medical Affairs priorities across the assigned portfolio. It partners with Global and Regional Medical Affairs leadership and cross-functional stakeholders to enable timely, high-quality execution of medical strategy embedded in overall portfolio strategy. This role leads end-to-end medical program management for the assigned portfolio, including annual planning, budget and resource coordination, governance, and delivery of key medical affairs outputs (insight and evidence generation plans, publication planning, and medical strategy documents), ensuring the alignment across global, regions, and key functions.

Responsibilities

• Lead the Medical Affairs Strategy Team (MAST) operating model for the assigned disease area(s) including team charter, membership, governance, standing agenda, decision capture, and action tracking
• Owns the structured integration and representation of Medical Affairs priorities, risks and decisions, as managed by MAST into cross-functional governance and decision making forums, such as International & US Brand Teams (IBT, USBT), R&D Product Strategy Teams (PST).
• Accountable to drive cross-functional execution of priorities across Medical Affairs (e.g., disease area, regional medical affairs, medical communications, medical information, etc) and key partners (Marketing, Market Access, HEOR/RWE, PV/Safety, Regulatory, Clinical Development, etc.) while ensuring compliance with relevant SOPs and governance
• Owns the Project Management and Process framework of key enterprise-wide initiatives such as Advisory Boards and cross-functional strategic initiatives (eg evidence gap analysis) and ensure alignment of scope, timelines, decision points, risks and accountabilities across 3M (Marketing, Medical, Market Access) strategic activities and other key functions such as R&D
• Own the annual medical planning process, tightly linked to Brand Planning and ensure integrated, timely delivery of strategy, tactical plans, evidence generation plans, insight plans, and publication plans.
• Lead the implementation and continuous improvement of global templates and business processes (annual plans, budget worksheets, trackers, and dashboards)
• Develop and maintain the integrated business process calendar to ensure key deliverables (evidence/insight milestones, congress planning, scientific communications, and core medical documents) are delivered on time with appropriate reviews and approvals.
• Ensure resource availability and lead mitigation in case of constraints
• Lead budget planning, tracking, and forecasting for medical affairs activities in partnership with Finance and Medical leadership
• Proactively identify, elevate and manage potential cross-functional execution risks and interdependencies
• Facilitate scenario planning for mitigation strategies across book of work to enable portfolio-level visibility, prioritization and decision-making
• Establish and monitor program-level metrics and dashboards (e.g., milestone delivery, budget, scientific communications execution) and provide concise, actionable readouts
• Coach and mentor program management colleagues and contribute to capability building, standardization, and best-practice sharing across Medical Program Management
• Be an ambassador for change initiatives, key communication messages and other initiatives critical for the success of Medical Affairs

Qualifications

• Bachelor's degree required
• 8+ years’ relevant experience in medical affairs operations/program management, cross-functional business operations, or related pharmaceutical/biotech experience
• Relevant CSL disease area experience desirable
• Demonstrated ability to lead complex, cross-functional initiatives in a matrix environment, including governance, senior stakeholder management, and influencing without authority
• Strong strategic thinking, problem-solving, and execution focus with the ability to translate strategy into integrated plans, milestones, and measurable outcomes
• Proficiency with project/program management tools (e.g., Smartsheet), timeline development (e.g., Gantt charts), and budget management; able to develop fit-for-purpose dashboards and reporting
• Different qualifications or responsibilities may apply based on local legal and/or educational requirements. Refer to local job documentation where applicable.

About CSL Behring

CSL Behring is a global biotherapeutics leader driven by our promise to save lives. Focused on serving patients’ needs by using the latest technologies, we discover, develop and deliver innovative therapies for people living with conditions in the immunology, hematology, cardiovascular and metabolic, respiratory, and transplant therapeutic areas. We use three strategic scientific platforms of plasma fractionation, recombinant protein technology, and cell and gene therapy to support continued innovation and continually refine ways in which products can address unmet medical needs and help patients lead full lives. CSL Behring operates one of the world’s largest plasma collection networks, CSL Plasma. Our parent company, CSL, headquartered in Melbourne, Australia, employs 32,000 people, and delivers its lifesaving therapies to people in more than 100 countries. To learn more about CSL, CSL Behring, CSL Seqirus and CSL Vifor visit https://www.csl.com/ and CSL Plasma at https://www.cslplasma.com/.

Our Benefits

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