Senior Manager, Global Clinical Supply Chain

Kiniksa Pharmaceuticals, Ltd.; Lexington (MA); Hybrid; USD 160,000 - 170,000; Full time

Job summary

Kiniksa Pharmaceuticals, Ltd. is seeking a Senior Manager, Clinical Supply Chain Management in Lexington, MA to lead end-to-end clinical supply activities across studies and programs.

The role requires coordinating with Clinical Operations, Quality, Regulatory, and CMC/Manufacturing, ensuring reliable supply and proactive risk mitigation in a fast-paced environment. Based in our Lexington office, this position emphasizes hands-on leadership, vendor governance, and collaboration with external

Qualifications

• BS/BA degree required with 4+ years in Clinical Supply Chain in biotech/pharma.
• Experience leading contract packaging and labeling governance and vendor performance.
• Proven ability to develop risk-based supply plans for studies across development stages.
• Strong understanding of global regulatory expectations for clinical supply distribution (US/EU/APAC).
• Knowledge of cGMP, GCP, GDP and transportation requirements for pharmaceutical materials.

Responsibilities

• Provide end-to-end clinical supply support for global studies.
• Align supply timelines and demand with study teams for new studies.
• Lead management of packaging, labeling, depots, and distribution vendors; drive KPIs.
• Oversee master schedule development for packaging campaigns and issue resolution.
• Support comparator sourcing, labeling, and distribution strategies across global sourcing scenarios.
• Translate study protocols into demand forecasts and communicate risks to stakeholders.
• Oversee labeling strategy and regulatory-compliant execution, including translations.
• Develop integrated supply plans and inventory governance; update project teams.
• Manage global distribution and 3PL relationships, including temperature-controlled shipments.
• Own risk management for clinical supply and escalation of critical issues.

Skills

Strategic planning

Forecasting

Vendor management

Cross-functional collaboration

IRT/IXRS

SMartsheet/Excel

Education

BS/BA in related field

Advanced degree (plus)

Tools

Smartsheet

Excel

ERP systems

Job description

Kiniksa Pharmaceuticals, Ltd. is seeking a Senior Manager, Clinical Supply Chain Management in Lexington, MA to lead end-to-end clinical supply activities across studies and programs.

The role requires coordinating with Clinical Operations, Quality, Regulatory, and CMC/Manufacturing, ensuring reliable supply and proactive risk mitigation in a fast-paced environment. Based in our Lexington office, this position emphasizes hands-on leadership, vendor governance, and collaboration with external