Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction‑associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH.
Madrigal’s medication, Rezdiffra (resmetirom), is a once‑daily, oral, liver‑directed THR‑β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c).
Our success is driven by our people. We are building a dynamic, inclusive, and high‑performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way.
Senior Manager of FP&A
The Senior Manager of FP&A will be a key member of Madrigal’s Finance team, serving as both a strategic business partner and a hands‑on leader of the financial planning and analysis processes supporting Madrigal’s G&A organization.
Key Responsibilities
- Strategic ELT Business Partnering : Serve as the strategic finance partner to numerous members of the Executive Leadership Team and their departments. Build trusted relationships with ELT members and department leaders, providing forward‑looking insights into planning, forecasting, variance analysis, and investment decisions, and proactively bringing recommendations that shape strategy and resource allocation.
- Technology & IT Finance : Partner with the CIO and IT leadership on technology spend planning, including software/SaaS licensing, infrastructure, IT services, and vendor contracts, as well as capital versus expense treatment of technology investments. Evaluate business cases, ROI, and total cost of ownership for major technology initiatives, and track spend against approved budgets.
- Month End Close & Spend Governance : Own the month‑end close process for G&A departments, ensuring accurate accrual, prepaid, and reclass entries in partnership with Accounting. Establish and reinforce spend governance, ensuring Purchase Orders are opened in line with approved budgets and proactively escalating unbudgeted commitments to business partners and Finance leadership.
- Budgeting and Forecasting : Lead the annual budget, quarterly forecast, and long‑range planning processes for G&A departments for all OpEx spend, inclusive of headcount forecasting, as well as capital expenditures. Drive continuous improvement of planning processes, models, timelines, and stakeholder engagement.
- Financial Reporting & Executive Communication : Own monthly and quarterly financial reporting, including actual‑versus‑budget/forecast reporting for business partners and quarterly LBE (Latest Best Estimate) reporting. Develop and present ELT‑ready materials that clearly communicate financial performance, key drivers, risks, and opportunities.
Required & Desired Qualifications
- Bachelor’s degree in accounting, finance, or related field; MBA, CPA, or CFA preferred.
- 8+ years of progressive finance/FP&A experience required, 2+ years in the pharma/biotech/life sciences industry preferred.
- Prior experience supporting a CIO / IT function strongly preferred, including technology spend planning, software and infrastructure costs, IT vendor management, and capitalization of internal‑use software.
- Demonstrated track record serving as a strategic partner to executive‑level leaders, with the executive presence to advise ELT members and the ability to manage multiple senior stakeholders and competing priorities.
- Expert proficiency with Excel and advanced PowerPoint skills, including the ability to build executive‑ready presentations.
- Strong communication skills, both written and verbal, and a desire to collaborate with colleagues across different functions.
- Ability to collaborate cross‑functionally and influence decisions at all levels of the organization, up to and including the ELT.
- Have a strong degree of self‑motivation, ownership, and flexibility, and the ability to proactively plan and prioritize workload in a fast‑paced environment.
- Experience with financial systems including Coupa, Concur, ERP systems (SAP, NetSuite, etc.), and consolidation systems (Datarails, Hyperion, OneStream, etc.).
- Strong understanding of US GAAP accounting, including capitalization of software and IT costs.
- Minimum requirement of 3 days in office each week.
As of the date of this posting, a good faith estimate of the current pay scale for this position, applicable to all candidates, is $151,214 - $177,203 per year. We comply with all applicable minimum wage laws.
Benefits
- Full-time employees receive equity, which we believe reinforces our ownership culture. Base salary is determined by several factors including the candidate’s qualifications, skills, education, experience, business needs and market demands.
- Full-time employees are also eligible for comprehensive benefits, including flexible paid time off, medical, dental, vision and life/disability insurance, and 401(k) offerings (i.e., traditional, Roth, and employer match) in accordance with applicable plans.
- We also offer additional voluntary benefits like supplemental life insurance, legal services, and other offerings.
- In addition, we offer mental health benefits through our Employee Assistance Program for employees and their family.
- The company also provides other benefits in accordance with applicable federal, state, and local laws.
Madrigal is committed to providing reasonable accommodations for individuals with disabilities throughout the hiring process. If you need assistance, please contact HR@madrigalpharma.com.
Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications, merit, and business need. Applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex gender identity, sexual orientation, national origin, age, disability, protected veteran or disabled status, or other characteristic protected by applicable federal, state, or local law.