Senior Manager, External Quality-Supply Chain

Socket.dev; Brisbane (CA); On-site; USD 173,000 - 199,000; Full time

Job summary

Nurix Therapeutics is seeking a Senior Manager, Supply Chain Quality Assurance to ensure quality and compliance across global supply chains, including CMOs, suppliers, warehouses, depots, and logistics providers. You will drive investigations, CAPA, and continuous improvement while collaborating with Regulatory Affairs and Manufacturing to support Nurix’s pipeline programs.

The role requires deep knowledge of FDA regulations, ICH guidelines, and GMP, with extensive experience in quality events,

Qualifications

• Bachelor’s degree in chemistry, pharmaceutical sciences, life sciences, engineering or related field.
• 5+ years of progressive Supply Chain Quality Assurance in pharma with global distribution.
• Experience managing outsourced manufacturing, testing, packaging and labeling and distribution.
• Thorough knowledge of FDA regulations (21 CFR Parts 210/211) and ICH GMP guidelines.
• Proven track record managing quality events, deviations, CAPA programs, and change control.
• Experience supporting regulatory inspections (FDA, EMA, or equivalent).
• Excellent project management with multiple deliverables.
• Strong verbal and written communication; able to present complex topics clearly.
• Willingness to travel domestically and internationally.

Responsibilities

• Provide Quality oversight of global supply chain operations supporting clinical programs.
• Ensure quality requirements in procurement, manufacturing, packaging, storage, transport and distribution.
• Oversee quality aspects of warehousing and distribution operations.
• Qualify, monitor, and maintain approval status of suppliers, CMOs, depots and logistics providers.
• Participate in supplier audits and quality risk assessments.
• Manage supplier quality agreements and periodic reviews.
• Ensure compliance with Good Distribution Practices.
• Oversee qualification of shipping lanes and transportation providers.
• Review shipping validation documentation.
• Assess quality impact of deviations through deviation reviews.
• Identify opportunities to simplify quality processes while maintaining compliance.
• Maintain knowledge of evolving regulatory expectations and translate to operational guidance.

Skills

Project management

Communication

Leadership

Collaboration

Education

Bachelor's degree in chemistry, pharmaceutical sciences, life sciences, engineering or related field

Job description

Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for patients with cancer and inflammatory diseases. Powered by a fully AI-integrated discovery engine capable of tackling any protein class, and coupled with unparalleled ligase expertise, Nurix’s dedicated team has built a formidable advantage in translating the science of targeted protein degradation into clinical advancements. Nurix aims to establish degrader-based treatments at the forefront of patient care, writing medicine’s next chapter with a new script to outmatch disease.

About the Position:

The Senior Manager, Supply Chain Quality Assurance is responsible for ensuring the quality and compliance of materials, products, and distribution activities throughout the global supply chain. This position provides quality oversight of contract manufacturers, suppliers, warehouses, packaging operations, depots and logistics providers to ensure compliance with applicable GMP, GDP, GCP (where applicable) and company quality standards.

This role partners with Supply Chain, Manufacturing, Regulatory Affairs, Technical Operations, Clinical, CMC, and external business partners ensuring the quality, compliance, and timely supply of clinical materials across Nurix’s pipeline programs.

Reporting to the Senior Director, Quality Assurance, the Senior Manager will apply sound independent judgment to drive timely identification, investigation, and resolution of quality events, while building a culture of continuous improvement and cross-functional collaboration.

Responsibilities:

• Provide Quality oversight of global supply chain operations supporting early and late-stage clinical programs.
• Ensure quality requirements are incorporated into procurement, manufacturing, packaging, storage, transportation and distribution activities.
• Oversee quality aspects of warehousing and distribution operations.
• Qualify, monitor, and maintain approval status of suppliers, CMOs, laboratories depots and logistics providers.
• Participate in supplier audits and quality risk assessments.
• Manager supplier quality agreements and ensure periodic review.
• Ensure compliance with Good Distribution Practices.
• Oversee qualification of shipping lanes and transportation providers.
• Review shipping validation documentation.
• Assess quality impact of shipping deviations through the review of shipping deviations, including review of temperature excursion investigations and product impact assessments.
• Identify continuous improvement opportunities to simply quality processes while maintaining compliance.
• Maintain current knowledge of evolving regulatory expectations and industry standards; translate requirements into practical operational guidance for the organization.

Required Qualifications:

• Bachelor’s degree in chemistry, pharmaceutical sciences, life sciences, engineering or a related
• 5+ years of progressive Supply Chain or Supply Chain Quality Assurance experience in the pharmaceutical or biopharmaceutical industry with global distribution activities.
• Demonstrated experience managing and directing activities of outsourced manufacturing, testing, packaging and labeling and distribution operations.
• Thorough knowledge of FDA regulations (21 CFR Parts 210/211) and ICH guidelines (Q7, Q8, Q9, Q10, Q11), and EudraLex - Volume 4 - Good Manufacturing Practice (GMP) and their practical application to CMC development.
• Proven track record managing quality events, deviations, CAPA programs, and change control in a clinical or commercial pharmaceutical setting.
• Experience supporting regulatory agency inspections (FDA, EMA, or equivalent).
• Excellent project management skills with the ability to manage multiple high-priority deliverables simultaneously.
• Strong verbal and written communication skills; able to present complex quality and compliance topics clearly to diverse stakeholders.
• Willingness to travel to CDMO and laboratory sites domestically and internationally, as

Preferred Qualifications:

• Experience in a clinical-stage biotech environment scaling quality operations through late-stage development and toward commercialization.
• Experience with electronic QMS platforms (e.g., Veeva Vault) and document management
• Expertise in both development-phase and pre-commercial-phase quality assurance standards and expectations.

Salary: $173,000 - $199,00

Fit with Nurix Culture and Values

• Strong team orientation; highly collaborative
• Solutions and results-oriented focus
• Hands‑on approach; resourceful and open to diverse points of view