Senior Manager, Epidemiology/Real-World Data and Analytics (Oncology)

Regeneron Pharmaceuticals; Sleepy Hollow (WY); On-site; USD 151,000 - 246,000; Full time

Benefits offered by this job

Annual bonuses

Equity awards

Pension or retirement benefits

401(k) company match

Health and wellness programs

Paid time off

Job summary

Regeneron Pharmaceuticals seeks a Senior Manager, Epidemiology in Sleepy Hollow, NY to drive real-world evidence for Oncology programs. You will design observational studies, support regulatory and payer submissions, and collaborate with HEOR colleagues to influence development and commercialization decisions.

This role emphasizes advanced analytics, regulatory readiness, and global HTA engagement, with on-site work four days per week in a science-driven environment.

Qualifications

• Hands-on drafting of technical design documents, study protocols and statistical analysis plans using real-world data, with peer-reviewed publications.
• Excellent communication to translate complex designs into clear insights for diverse audiences.
• Experience conducting epidemiology and RWE research in oncology and related endpoints.
• Experience applying advanced analytical methods to large healthcare datasets (causal inference, bias assessment, robust estimation).
• Familiarity with global HTA and payor evidence needs, value and reimbursement strategies.
• 2+ years across academia, pharma/biotech, or consulting environments.

Responsibilities

• Generate high-quality observational research using diverse real-world data sources to support development and commercial strategies.
• Evaluate and implement emerging design and analytic methods to strengthen RWE capabilities.
• Synthesize and assess scientific evidence for regulatory and payor submissions and internal needs.
• Support global HTA/payor submissions with epidemiology and RWE inputs for value dossiers.
• Provide technical epidemiology expertise to clinical development and external control arms.
• Stay current with evolving regulatory and payor expectations for RWE and guide internal teams.
• Participate in epidemiologic design discussions in peer review forums.
• Drive projects forward with a growth mindset and prioritized planning.

Skills

Epidemiology methods

RWE study design

Scientific writing

Communication skills

Large healthcare data

Education

Doctoral degree in epidemiology

Job description

Build our future together:

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Senior Manager, Epidemiology for our Health Economics and Outcomes Research team to support our Oncology programs. In this role, you will generate real-world evidence that influences the development and commercialization of innovative oncology therapies while collaborating with HEOR colleagues and key collaborators.

This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

When & where

• Location: Sleepy Hollow, NY


• Work model/flexibility: On-site 4 days/week

Discover your rol e:

• Generate high-quality observational research using diverse real-world data sources to support development and commercial strategies


• Evaluate and implement emerging design and analytic methods to strengthen our RWE capabilities


• Synthesize and critically assess scientific evidence for regulatory and payor submissions, press releases, and internal business needs


• Support global HTA and payor submissions with epidemiology and RWE inputs for value dossiers and reimbursement packages


• Provide technical expertise to clinical development and evidence generation, and external control arms and hybrid approaches


• Stay current with evolving regulatory and payor expectations for RWE and guide internal teams on the implications


• Participate in epidemiologic design discussions in a peer review forum


• Drive projects forward with a growth mindset, proactively identifying solutions and managing priorities

This role requires

• Doctoral degree in epidemiology or a related subject area (e.g., health services research, public health), plus at least 2 years of experience across academia, pharma/biotech, or consulting


• Hands-on experience drafting technical design documents, study protocols and/or statistical analysis plans using real-world data, with a record of peer-reviewed publications


• Excellent communication skills, with the ability to translate complex designs and findings into clear, actionable insights for diverse audiences


• Experience conducting epidemiology and RWE research in oncology, including familiarity with cancer treatment paradigms and oncology endpoints is preferred


• Experience applying advanced analytical methods to large healthcare datasets, including causal inference, bias assessment, and robust estimation is preferred


• Familiarity with global HTA and payor evidence needs, value and reimbursement strategies are preferred

We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role:

• annual bonuses or other incentive plans


• equity awards


• pension or retirement benefits


• 401(k) company match


• health and wellness programs


• fitness centers


• insurance benefits (e.g. medical, dental, vision, life and disability)


• paid time off


• family support benefits

For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually)

$150,500.00 - $245,500.00