Senior Manager, Cell Therapy Hub

AstraZeneca GmbH; Wilmington (DE); On-site; USD 138,000 - 207,000; Full time

Job summary

AstraZeneca seeks a Senior Manager, Cell Therapy Hub to lead patient coordination and vein-to-vein workflows across regions. You will work with Clinical Operations, Site Management, Supply Chain, and IT to support treatment sites and patients, ensuring a seamless patient journey from registration to infusion.

The role emphasizes SOP development, training materials, and continuous improvement while maintaining compliance with regulatory standards. Travel >50% will be required.

Qualifications

• Experience managing complex patient journeys and coordinating across cross-functional teams.
• Strong communication, collaboration, and relationship-building skills.
• Familiarity with multiple digital platforms and systems.
• Ability to work independently in a fast-paced, patient-focused environment.
• Experience supporting regulated healthcare programs and SOPs development.

Responsibilities

• Serve as single point of contact for treatment site collaborators within assigned regions.
• Manage patient vein-to-vein workflows from registration to infusion.
• Identify and resolve patient-related issues and provide coverage across regions.
• Collaborate with Clinical Operations, Site Management, Supply Chain, and other teams to meet needs.
• Develop and maintain SOPs and training materials for the Cell Therapy Hub.
• Drive process improvements and ensure compliance with regulations.

Skills

Communication

Collaboration

Relationship-building

Cross-functional coordination

Patient journey management

Project management

Independent work

Digital platforms

Education

Bachelor's degree (Life Sciences/Healthcare/Nursing/Business)

Advanced degree (PharmD/NP/PA/ Biomedical Eng.)

Job description

At AstraZeneca, we follow the science to explore and innovate, working to treat, prevent, modify, and ultimately cure some of the world's most complex diseases. Within our Cell Therapy organization, we are advancing cutting-edge science and technology to transform outcomes for patients with cancer.

We are seeking a Senior Manager, Cell Therapy Hub to join our Cell Therapy Patient Operations team supporting clinical and commercial cell therapy production across multiple sites. This field-based role serves as a critical connection point between treatment centers, healthcare professionals, patients, and AstraZeneca cross-functional teams, ensuring a seamless vein-to-vein (V2V) patient journey.

The successful candidate will demonstrate expertise in patient coordination, provider support, and cell therapy operations while delivering an exceptional experience for treatment sites and patients. Reporting to the Senior Director, Cell Therapy Hub, this position plays a key role in advancing life-changing cell therapy treatments through operational excellence and patient-centered support.

As the Senior Manager, Cell Therapy Hub, you will:

• Serve as a trusted, knowledgeable single point of contact for treatment site collaborators, improving the site experience through the AstraZeneca Cell Therapy Hub.
• Independently manage all patient vein-to-vein workflows from patient registration through infusion within assigned geographic regions.
• Identify, raise, and resolve patient-related issues while providing coverage support across regions as needed.
• Partner closely with cross-functional teams including Clinical Operations, Site Management, Supply Chain, Medical Affairs, Information Technology, Commercial, and other team members to meet patient and healthcare provider needs.
• Communicate critical patient-related information to site collaborators with empathy and professionalism while managing expectations.
• Collaborate with Regional and Territory Operations Managers to ensure site logistics, personnel readiness, and Chain of Identity (COI)/Chain of Custody (COC) access to AstraZeneca digital platforms.
• Coordinate communication and resolution of issues related to cellular starting materials, investigational medicinal products (IMPs), and associated supplies.
• Partner with Quality Assurance, Manufacturing, and Supply Chain teams on out-of-specification (OOS) communications, product recalls, and product-related site issues.
• Develop and maintain internal and external standard operating procedures (SOPs), training materials, and operational documentation related to the Cell Therapy Hub.
• Demonstrate proficiency in all Cell Therapy Hub systems, including Customer Portal and telephony platforms, as well as associated SOPs, work instructions, and business processes.
• Drive continuous improvement initiatives and contribute to the development of innovative solutions that enhance the patient care experience.
• Maintain compliance with AstraZeneca policies, regulatory standards, and Cell Therapy Hub procedures.
• Support implementation and rollout of process improvements and operational changes across assigned treatment sites.
• Demonstrate a strong commitment to patients by consistently reflecting AstraZeneca values in daily interactions and decision-making.
• Perform other duties as assigned while maintaining adherence to applicable regulations and SOPs.
• Travel greater than 50% as required.

Essential Skills/Experience

• Bachelor's degree in Life Sciences, Healthcare, Nursing, Business, or a related field, or equivalent combination of education and experience.
• Minimum of 4 years of experience within a cell therapy program, healthcare system, or regulated healthcare environment in roles such as:
• Research Coordinator
• Nurse Coordinator
• Apheresis Nurse
• Cell Laboratory Professional
• Quality Manager
• Other patient-focused cell therapy or oncology operational roles
• Experience managing complex patient journeys and coordinating across multiple cross-functions
• Ability to solve site-facing operational challenges and effectively navigate organizational complexity.
• Strong communication, collaboration, and relationship-building skills.
• Experience working across multiple digital platforms and systems.
• Strong organizational and project management capabilities with exceptional attention to detail.
• Ability to work independently in a fast-paced, patient-focused environment.

Desirable Skills/Experience

• Advanced degree in Life Sciences, Healthcare, Engineering, or a related field (e.g., PharmD, Nurse Practitioner, Physician Assistant, Biomedical Engineering).
• Experience supporting cell and gene therapy programs.
• Experience working with critical raw material suppliers and/or contract manufacturing organizations (CMOs).
• Knowledge of oncology, immuno-oncology, and cellular therapy treatment pathways.
• Familiarity with GMP, GCP, and regulated healthcare environments.
• Experience developing SOPs, training programs, and process improvement initiatives.

Why AstraZeneca

Here, courage, curiosity, and collaboration fuel a relentless focus on transforming cancer outcomes, powered by a pipeline that fuses innovative science with advanced technology. You will work in an environment where unexpected teams come together to spark bold ideas, backed by meaningful investment and a clear path from discovery to impact. We value kindness alongside ambition, and we empower leaders at every level to ask sharp questions, take smart risks, and turn data into decisions that help patients sooner.

Compensation & Benefits

The annual base pay for this position ranges from $137,937.60 - $206,906.40. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility.

Date Posted

16-Sep-2026

Closing Date

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.