Senior Manager, Business Operations, G&A

Revolution Medicines; San Francisco (CA); On-site; USD 164,000 - 205,000; Full time

Job summary

Revolution Medicines is seeking a Senior Manager, Business Operations – G&A to partner with Finance, Legal, HR, IS, Facilities and Corporate Affairs. Lead cross-functional initiatives, develop business cases, and drive operational excellence in a fast-growing biotech environment.

The role emphasizes project management, data-driven decision making, and stakeholder collaboration, reporting to the Director, Business Operations – G&A in a dynamic, patient-centric culture.

Qualifications

• BS/BA in related field with 8+ years of experience or Master’s with 6+ years of experience.
• Experience in business operations, G&A operations, operational excellence, project management, or similar roles in biotech/pharma/life sciences.
• Proven success leading complex cross-functional initiatives with multiple stakeholders.

Responsibilities

• Plan, coordinate, and execute prioritized strategic and operational initiatives across G&A.
• Lead cross-functional projects, define timelines, deliverables, risks, and success metrics.

Skills

Project management

Cross-functional

Data analysis

Process improvement

Stakeholder management

G&A operations

Education

BS/BA + 8+ years

MS + 6+ years

Tools

Microsoft Office

Confluence

Smartsheet

MS Project

Visio

Office Timeline

Job description

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity

This is an exciting opportunity to be a key member of the Business Operations – G&A team. Embedded within the Commercialization Effectiveness & Operations function, we partner across Global G&A and Commercialization‑adjacent teams, including Finance, Legal, Human Resources, and Information Systems, Facilities, and Corporate Affairs. Our work brings together G&A operations and readiness, global commercialization contracts operations, change and capability enablement, as well as execution of prioritized cross‑functional initiatives to strengthen organizational readiness, improve operational clarity, and support RevMed’s continued growth.

Senior Manager, Business Operations – G&A

The Senior Manager, Business Operations - G&A serves as a trusted business operations partner to G&A teams, enabling teams to execute against strategic priorities, foster cross‑functional collaboration, and implement fit‑for‑purpose operational solutions. This individual brings strong project management, business operations, analytical and process improvement capabilities. They are comfortable evaluating complex business processes, identifying opportunities for optimization, translating business requirements into actionable solutions, and leveraging data and insights to support decision‑making.

Reporting to the Director, Business Operations – G&A, the ideal candidate is equally comfortable moving between planning, project execution, process improvement, data analysis, and stakeholder problem‑solving, serving as both an operational project lead and analytical thought partner within an exciting, dynamic and fast‑moving environment.

Key Responsibilities

• Partner with Business Operations - G&A team members and global G&A teams to plan, coordinate, and execute prioritized strategic and operational initiatives that support departmental and company priorities.
• Lead complex cross‑functional projects, workstreams and working sessions, ensuring alignment on objectives, timelines, deliverables, dependencies, risks, mitigation plans, and success measures, ultimately driving project progress.
• Collaborate across Finance, Legal, Human Resources, Information Systems, Corporate Affairs, Facilities, Commercialization and other functions to drive alignment and execution.
• Support development of project charters, change management plans, stakeholder engagement strategies, and communications approaches.
• Lead change management activities for assigned initiatives, including stakeholder engagement, communications, adoption planning, and feedback loops to support successful implementation of key initiatives.
• Develop business cases and project proposals, process analyses, operational metrics, reports/dashboards, and decision‑ready insights and recommendations.
• Help design, document and operationalize processes, governance mechanisms, and operating rhythms for assigned initiatives and cross‑functional workstreams.
• Create and maintain project documentation, including project charters, plans, timelines, status reports, process maps, meeting materials, and executive communications.
• Develop visual process documentation and operational tools to support business process design, continuous improvement, and cross‑functional clarity.
• Partner with external consultants and vendors supporting strategic business operations and enablement initiatives, ensuring alignment with project objectives and expected outcomes.
• Drive measurable outcomes through disciplined project management, clear accountability, data‑informed decision making, and proactive management of risks, dependencies, decisions, and execution against defined success metrics.
• Foster open, collaborative, and solutions‑oriented partnerships across stakeholder groups while embodying RevMed’s core values of patient‑centricity, collaboration, integrity, innovation, and inclusion.
• Contribute to the evolution of Business Operations tools, processes, and best practices to support scalable and effective G&A operations.
• Demonstrate sound judgment and adaptability in ambiguous and rapidly changing environments.

Required Skills, Experience and Education

• BS/BA degree in a related discipline with 8+ years of relevant experience, or Master’s degree with 6+ years of relevant experience.
• Experience in business operations, G&A operations, operational excellence, project management, management consulting, or similar roles within the biotechnology, pharmaceutical, or life sciences industry.
• Demonstrated success leading complex cross‑functional initiatives involving multiple stakeholders and business functions.
• Strong understanding of corporate business processes and systems supporting functions such as Finance, Human Resources, Legal, Procurement, Information Systems, and related G&A operations.
• Strong project management capabilities, including planning, prioritization, risk management, issue resolution, and execution.
• Experience analyzing and documenting business processes, requirements, workflows stakeholder needs, pain points and operating models to support process improvement and organizational effectiveness initiatives.
• Demonstrated ability to use qualitative and quantitative data to identify issues, evaluate alternatives, develop recommendations, and support decision‑making.
• Excellent analytical, problem‑solving, and organizational skills, with the ability to balance strategic context and operational detail.
• Strong written and verbal communication skills, including the ability to synthesize complex information into clear, concise, and actionable recommendations.
• Proven ability to influence and align diverse stakeholder groups without direct authority.
• Demonstrated ability to work independently and effectively in a fast‑paced, evolving environment with changing priorities.
• Growth mindset with a focus on continuous improvement, innovation, and operational excellence.
• Demonstrated ability to leverage approved AI‑enabled tools responsibly to improve productivity, streamline workflows, synthesize information, enhance project deliverables, and identify opportunities for operational efficiency while maintaining sound judgment, quality, and confidentiality and alignment with company policies.
• Strong proficiency with Microsoft Office applications and collaboration platforms (e.g., Teams, Confluence, Egnyte).
• Experience with process mapping, workflow visualization, and project management tools such as Visio, Smartsheet, MS Project, Office Timeline, or similar applications.

Preferred Skills

• PMP (Project Management Professional) or other PM certification or equivalent is a plus
• Prior experience in management consulting, business transformation, or enterprise change management.
• Experience with operational analysis, process improvement frameworks, operational metrics, dashboard development, or business intelligence/reporting tools.
• Experience supporting commercialization readiness, organizational scaling, or operational maturity initiatives within a high‑growth biotechnology or pharmaceutical organization.
• Experience working in global or geographically distributed organizations.

Base Pay Salary Range

The base pay salary range for this full‑time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job‑related skills, experience, market dynamics, and relevant education or training.

Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Base Pay Salary Range
$164,000 - $205,000 USD

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCA Notice and Privacy Policy. For additional information, please contact [e-mail].

Revolution Medicines acknowledges not obligating unsolicited employment offers and not mandating the provision of financial information, mandatory equipment purchase, mandatory fee payments. Not mandating mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory mandatory