Senior Manager, Biostatistics

Eikon Therapeutics, Inc.; Jersey City (NJ); On-site; USD 170,000 - 205,000; Full time

Benefits offered by this job

401(k) with company match

Medical, dental, vision insurance 95–0

Mental health and wellness benefits

Paid time off and holiday policies

Life/AD&D insurance

Job summary

Eikon Therapeutics, Inc. is seeking a Senior Manager, Biostatistics to lead statistical efforts across clinical trials and experimental studies in a biopharmaceutical setting. You will design analyses, supervise the analysis lifecycle, and guide cross-functional teams to support evidence-based decisions.

The role emphasizes oncology trial expertise, regulatory familiarity, and strong leadership, with onsite presence at our New Jersey office to enable high-performance delivery and team growth.

Qualifications

• PhD or equivalent with 3+ years clinical research and drug development, or MS with 7+ years experience.
• Strong proficiency in R within Posit/RStudio ecosystem.
• Experience with oncology trials and regulatory guidelines (ICH, FDA).
• Ability to own full analysis lifecycle and mentor teammates.

Responsibilities

• Collaborate with cross-functional teams to design trials, endpoints and analyses.
• Lead statistical analysis plans and reporting sections for regulatory submissions.
• Perform advanced analyses and interpret results for decision making.
• Mentor biostatisticians and statistical programmers.

Education

PhD in statistics/biostatistics or related discipline

MS in statistics/biostatistics

Tools

R (Posit/RStudio)

Job description

Eikon Therapeutics is a new biopharmaceutical company employing revolutionary technology at the intersection of chemistry, engineering, computation, and biology to discover novel treatments for life-threatening diseases. Eikon’s discovery platform is built on groundbreaking innovations from its founders (Nobel Prize, 2014), culminating in the creation of microscopes which enable real time, molecular-resolution measurements of protein movement in living cells, thereby unlocking otherwise intractable classes of proteins as drug targets.

Position

We are seeking a skilled and highly motivated Senior Manager, Biostatistics to join our talented team. The successful candidate will contribute their statistical expertise and strategic thinking to the design, execution, and analysis of clinical trials and experimental studies. In collaboration with cross-functional teams, you will lead statistical efforts that facilitate evidence-based conclusions and guide our research and development initiatives.

About You

The ideal candidate for this role should possess a proven track record of designing and analyzing clinical trials and experimental studies, particularly within the biotechnology, pharmaceutical, or related industries. This candidate excels in leading interdisciplinary teams to design studies, developing statistical analysis plans, performing advanced statistical analyses, and providing guidance to team members. Their proficiency in statistical programming languages, understanding of regulatory guidelines, and excellent communication skills are essential for conveying complex statistical concepts to non-technical stakeholders. The ideal candidate also demonstrates leadership capabilities and a deep knowledge of emerging trends and best practices in biostatistics, statistical tools, and software.

This role will require a minimum of 3 day a week of onsite presence (or more as business needs require) in our New Jersey office to ensure effective management, operational excellence and high-performance delivery of clinical studies and to support the expected significant team growth & collaboration.

What You’ll Do

• Collaborate with interdisciplinary teams to design clinical trials, experiments, and studies, ensuring appropriate statistical methodologies are employed.
• Lead the development of statistical analysis plans, including endpoints, sample size determination, randomization strategies, and statistical methodologies.
• Perform advanced statistical analyses on complex datasets, interpreting results and drawing actionable conclusions.
• Provide guidance and mentorship to biostatisticians and statistical programmers within the team.
• Contribute to regulatory submissions by providing statistical expertise and preparing relevant sections of documents.
• Stay current with emerging trends and best practices in biostatistics and their application in the biotechnology field.
• Drive the implementation and utilization of advanced statistical tools and software.

Qualifications:

• PhD or equivalent degree in statistics/biostatistics or related discipline with a minimum of 3 years of clinical research and drug development experience, or a Master's degree with a minimum of 7 years relevant work experience.
• Deep, hands‑on proficiency in R within the Posit/RStudio ecosystem (R Markdown, Shiny, tidyverse).
• Substantial oncology trial experience — familiarity with standard oncology designs and endpoints (RECIST, dose‑escalation/optimization designs such as BOIN, biomarker‑driven subgroup work).
• Demonstrated ability to independently own the full analysis lifecycle, from raw data through exploratory analysis to finished output.
• Strong understanding of regulatory guidelines (ICH, FDA, etc.) and experience authoring statistical analysis plans and reporting via tables, listings, and figures.
• Experience with Bayesian statistics and adaptive trial designs (e.g., BOIN‑type dose‑escalation, dose‑optimization frameworks).
• Excellent communication skills, including translating statistical findings for non-technical stakeholders.
• Demonstrated leadership capabilities, including the ability to lead and mentor a team.
• Experience contributing statistical analysis to peer‑reviewed clinical publications or conference presentations (e.g., trial results manuscripts, oncology conference abstracts and posters).

At Eikon, employee compensation also includes bonus and equity compensation, in addition to several generous benefit programs, including:

• 401k plan with company matching
• Medical (premiums covered by Eikon at 95%), dental and vision insurance (premiums covered by Eikon at 100%)
• Mental health and wellness benefits
• Weeklong summer and winter holiday shutdowns
• Generous paid time off and holiday policies
• Life/AD&D Insurance (premiums covered by Eikon at 100%) and optional supplemental employee‑paid life/AD&D policies
• Enhanced parental leave benefit
• Daily subsidized lunch program when on‑site

The expected salary range for this role is $170,000 to $204,750 depending on skills, competency, and the market demand for your expertise.

Eikon is proud to be an equal opportunity employer and will consider all qualified applicants for employment.

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey.Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiringprocess or thereafter. Any information that you do provide will be recorded and maintained in aconfidential file.

As set forth in Eikon Therapeutics’s Equal Employment Opportunity policy,we do not discriminate on the basis of any protected group status under any applicable law.

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection.As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measurethe effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categoriesis as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

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