Senior Genomics Data Platform Scientist

The University of North Carolina at Chapel Hill; North Carolina; On-site; USD 110,000 - 150,000; Full time

Job summary

The Senior Computational Scientist at The University of North Carolina at Chapel Hill's Lineberger Comprehensive Cancer Center leads development of software for the Initiative for Generative Immunotherapy. You will automate sequencing data handling, build an internal sample/data system, and create a public data portal for researchers to browse and download data.

The role partners with bioinformaticians, clinicians and researchers to ensure data sharing complies with consent and funder rules, and

Qualifications

• Experience building web applications with a modern front-end framework (e.g., React, Vue, or Svelte, with TypeScript), including interfaces for searching, filtering, and visualizing data.
• Experience automating data handling (ingestion, validation, transfer, cataloguing, release) for large scientific or clinical datasets.
• Working knowledge of high-throughput sequencing data, including WGS, WES, bulk RNA-seq, and single-cell, and the associated file formats and standards (e.g., FASTQ, BAM/CRAM, VCF, h5ad/AnnData, GA4GH), enough to work directly with bioinformaticians on pipeline inputs and outputs.
• Facility with modern AI methods and software process automation.
• Attention to detail and ability to work simultaneously on multiple priorities.
• Analytical capabilities, including the ability to think critically and strategically and to propose and implement change.
• Excellent presentation, communication, management, and mentorship skills.

Responsibilities

• Automate data handling for sequencing analyses.
• Build an internal system for tracking samples and data.
• Develop a public web portal for researchers to browse and download data.

Skills

React/Vue/Svelte

Data automation

Genomics data formats

AI methods

Attention to detail

Analytical thinking

Communication/mentorship

Education

PhD in Computer Science/Bioinformatics/Data Science

Tools

Python

Nextflow

Snakemake

FastAPI

Django

Node.js

PostgreSQL

REST/GraphQL

D3/Plotly/Vega

Globus/Aspera

Docker/Kubernetes

Job description

The Senior Computational Scientist at The University of North Carolina at Chapel Hill's Lineberger Comprehensive Cancer Center leads development of software for the Initiative for Generative Immunotherapy. You will automate sequencing data handling, build an internal sample/data system, and create a public data portal for researchers to browse and download data.

The role partners with bioinformaticians, clinicians and researchers to ensure data sharing complies with consent and funder rules, and