Senior Engagement Manager - Commercial Strategy

Syneos Health, Inc.; San Francisco (CA); On-site; USD 210,000 - 258,000; Full time

Benefits offered by this job

Health benefits (Medical, Dental, Vis​

401k Company match

Flexible PTO & sick time

Job summary

Syneos Health, Inc. is seeking an Senior Engagement Manager - Commercial Strategy in San Francisco to lead client engagements, manage teams, and shape commercial strategies for biopharmaceutical brands.

You will supervise consulting staff, mentor junior members, and ensure on‑time, on‑budget delivery while pursuing follow‑on opportunities. The role emphasizes cross‑functional collaboration with client executives, development of analytical frameworks, and revenue forecasting across product

Qualifications

• 5+ years of life science consulting experience.
• 2+ years of management/leadership experience in a consulting firm.
• Experience in creating and evaluating commercial strategy for pharmaceutical brands.

Responsibilities

• Coach and mentor junior team members to extend their skills and responsibilities; conduct performance reviews & support recruitment/retention.
• Develop business strategy through researching product portfolio, forecasting revenue, market sizing and regression.
• Work directly with clients and managing directors to set project objectives, develop analytical frameworks, manage team responsibilities, and maintain timeline.
• Elevate new business opportunities through follow‑on work, product enhancements or additional service offerings.
• Lead team members in complex analysis and problem solving including structuring, techniques, synthesis, and client implications.
• 5+ years of experience in life science consulting with increasing seniority; 2+ years in management/leadership.

Skills

Leadership experience

Strategic planning

Client relationship management

Team mentorship

Revenue forecasting

Market sizing

Project management

Job description

Senior Engagement Manager - Commercial Strategy

Updated: November 2, 2026
Location: San Francisco, CA, United States
Job ID:19318-OTHLOC-CIxvYfws

You’re driven, resourceful, and above all else – remarkably smart.

In this role, you will build relationships (internally and externally), identify client needs, design strategic and innovative solutions, and deliver client contracts on time and on budget. As a member of the management team, you will be responsible for ensuring a superior client experience while developing the skills and supervising the work of consulting staff team members. You will:

• Coach and mentor junior team members to extend their skills and responsibilities as appropriate, conduct performance reviews & support overall recruitment/retention efforts
• Develop business strategy through conducting primary and secondary research relating to product portfolio and planning including forecasting revenue, market sizing and regression
• Work directly with clients and managing directors to set project objectives, develop analytical frameworks, manage team responsibilities, and maintain timeline
• Elevate new business opportunities through the identification of follow-on work, product enhancements or additional service offerings
• Leading team members in complex analysis and problem-solving including problem structuring, analytical techniques, synthesis, and client implications
  
• 5+ years of experience in life science consulting, with increasing levels of responsibility/exposure to senior leadership
• 2+ years of management/leadership experience in a consulting firm
  

Desired Requirements:

• Experience in creating and evaluating commercial strategy for pharmaceutical brands

The annual base salary for this position ranges from $210,000 to $258,000. The base salary range represents the anticipated low and high of the Syneos Health range for this position. Actual salary will vary based on various factors such as the candidate's qualifications, skills, competencies, and proficiency for the role. In addition, some positions may include eligibility to earn commissions/bonus based on company and / or individual performance.

At Syneos Health, we are dedicated to building a diverse, inclusive and authentic workplace. If your past experience doesn’t align perfectly, we encourage you to apply anyway. At times, we will consider transferable skills from previous roles. We also encourage you to join our Talent Network to stay connected to additional career opportunities.

Why Syneos Health? Here, you're a part of the big picture. You will collaborate with colleagues across clinical and commercial disciplines to guide premarket development through post-market commercial strategy. Every project is a chance to solve a new challenge, learn from your colleagues, and advance your career. The diversification and breadth of our new and existing partnerships create a multitude of career paths and employment opportunities. Join our game-changing, global company dedicated to creating better, smarter, faster ways to get biopharmaceutical therapies to patients. Experience the thrill of knowing that your everyday efforts are contributing to improving patients' lives around the world.

W o r k H e r e M a t t e r s E v e r y w h e r e | How are you inspired to change lives?

Syneos Health companies are affirmative action/equal opportunity employers (Minorities/Females/Veterans/Disabled)

At Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance. We reward and recognize our people by providing valuable benefits and a quality-of-life balance. The benefits for this position will include a competitive compensation package, Health benefits to include Medical, Dental and Vision, Company match 401k, flexible paid time off (PTO) and sick time. Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work. Syneos Health complies with all applicable federal, state, and municipal paid sick time requirements.

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.

Discover what our more than 25,000 employees already know: work here matterseverywhere. We work hard,and smart, all in the name of getting much-needed therapies to thosewho need them most. A career with Syneos Health means your everyday workimprovespatients’ lives around the world. Selecting us as an employer secures acareer inwhich you’re guaranteed to:

Syneos Health® is a leading fully integrated biopharmaceutical solutions organization builtto accelerate customer success. We translate unique clinical, medical affairs and commercialinsights into outcomes to address modern market realities. To learn more visit syneoshealth.com .

Syneos Health is an Equal Opportunity Employer. All qualified applicants will receiveconsideration for employment without regard to race, color, age, religion, marital status,ethnicity, national origin, sex, gender, gender identity, sexual orientation, protectedveteran status, disability or any other legally protected status and will not bediscriminated against. If you are an individual with a disability who requires reasonableaccommodation to complete any part of our application process, including the use of thiswebsite, please contact us at: Email: [emailprotected] One of our staff members willwork with you to provide alternate means to submit your application.