Senior Director Type 2 Immunology

Sanofi; Cambridge (MA); On-site; USD 206,000 - 298,000; Full time

Job summary

Sanofi Cambridge is seeking a Senior Director of Type 2 Immunology to lead cutting-edge translational and preclinical research, shaping clinical development strategies within a world-class immunology portfolio.

You will drive strategy, mentor a high-performing team, and partner with Clinical Development to translate discoveries into clinical hypotheses, advancing patient outcomes across dermatology, gastroenterology, respiratory, and rheumatology.

Qualifications

• PhD in immunology, molecular biology, or related field with 12+ years in pharma/biopharma.
• Deep expertise in Type 2 inflammatory biology and translational research.
• Proven ability to lead cross-functional R&D teams and translate findings to clinical strategy.
• Strong publication record in high-impact journals.

Responsibilities

• Execute and refine the Type 2 Immunology research strategy, identifying novel biological targets and therapeutic hypotheses to advance the pipeline.
• Drive long range research planning, portfolio prioritization, and investment decisions across preclinical and translational programs.
• Represent Type 2 Immunology research in senior leadership forums, governance committees, and pipeline review boards.
• Oversee preclinical and translational research programs, from target identification and validation through to candidate nomination.
• Lead mechanism of action studies and disease biology investigations to deepen understanding of Type 2 inflammatory pathways in both preclinical and translational settings.
• Drive biomarker identification, development, and qualification strategies to support patient stratification, proof of concept, and clinical decision making.
• Ensure scientific rigor and innovation across all stages of the drug discovery and development continuum.
• Support our development and medical colleagues in championing investigator initiated studies and collaborative research programs that generate mechanistic and clinical insights.
• Partner with Clinical Development and Regulatory Affairs to translate preclinical findings into clinical hypotheses and study designs.
• Oversee the scientific interpretation of clinical data to inform pipeline progression and lifecycle decisions.
• Establish and manage strategic research collaborations with leading academic institutions, research consortiums, and external scientific networks.
• Identify and evaluate external innovation opportunities, including licensing, codevelopment, and research alliances.
• Represent Sanofi in scientific advisory boards, research consortiums, and industry academic partnerships to advance the field.
• Lead a high impact publication strategy, ensuring timely and rigorous dissemination of research findings in top tier peer reviewed journals.
• Represent Sanofi as a scientific thought leader at national and international research conferences and symposia.
• Shape the external scientific narrative for Type 2 Immunology through white papers, review articles, and engagement with the broader research community.
• Lead, mentor, and develop a high performing team of research scientists, with an ingrained drug hunting culture.
• Foster a culture of scientific excellence, intellectual curiosity, collaboration, and accountability.
• Set clear research objectives, provide ongoing scientific guidance, and support career development and succession planning.

Skills

Immunology expertise

Translational leadership

Big data analytics

Cross-functional leadership

Scientific communication

Education

PhD in immunology or related field

Job description

Job title: Senior Director Type 2 Immunology Location: Cambridge, MA

About the job

We have an exciting opportunity to join Sanofi's Type 2 Immunology cluster. This role sits at the intersection of cutting-edge preclinical research and clinical development, offering a unique platform to shape the trajectory of one of the industry's most compelling immunology portfolios. Working at our Cambridge Crossing research campus, you will contribute to a team with deep commitment to scientific excellence and patient impact across dermatology, gastroenterology, respiratory, and rheumatology. The Senior Director, Type 2 Immunology is a senior research leadership role responsible for driving scientific discovery, translational medicine, and research innovation within Sanofi's Type 2 Immunology portfolio. Reporting directly to the Senior Cluster Head, Type 2 Immunology, this individual will lead cutting edge research programs, identify and validate novel therapeutic targets, and oversee the translation of scientific insights into clinical development strategies. This role serves as a principal scientific authority in the Type 2 inflammatory disease and will be instrumental in shaping Sanofi's long term research vision in this space, and beyond. The successful candidate will leverage Sanofi's extensive technical capabilities, including AI enabled platforms, single cell technologies, and multiomic approaches, while collaborating closely with Development, Medical Affairs, and Commercial teams. This is an opportunity to make a meaningful scientific and strategic contribution within a highly collaborative, cross functional environment. Join the engine of Sanofi’s mission — where deep immunoscience meets bold, AI-powered research. In R&D, you’ll drive breakthroughs that could turn the impossible into possible for millions.

About Sanofi

We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.

Main Responsibilities

• Execute and refine the Type 2 Immunology research strategy, identifying novel biological targets and therapeutic hypotheses to advance the pipeline.
• Drive long range research planning, portfolio prioritization, and investment decisions across preclinical and translational programs.
• Monitor and integrate emerging scientific advances, competitive intelligence, and unmet medical needs to continuously evolve the research agenda.
• Represent Type 2 Immunology research in senior leadership forums, governance committees, and pipeline review boards.
• Oversee preclinical and translational research programs, from target identification and validation through to candidate nomination.
• Lead mechanism of action studies and disease biology investigations to deepen understanding of Type 2 inflammatory pathways in both preclinical and translational settings.
• Drive biomarker identification, development, and qualification strategies to support patient stratification, proof of concept, and clinical decision making.
• Ensure scientific rigor and innovation across all stages of the drug discovery and development continuum.
• Support our development and medical colleagues in championing investigator initiated studies and collaborative research programs that generate mechanistic and clinical insights.
• Partner with Clinical Development and Regulatory Affairs to translate preclinical findings into clinical hypotheses and study designs.
• Oversee the scientific interpretation of clinical data to inform pipeline progression and lifecycle decisions.
• Establish and manage strategic research collaborations with leading academic institutions, research consortiums, and external scientific networks.
• Identify and evaluate external innovation opportunities, including licensing, codevelopment, and research alliances.
• Represent Sanofi in scientific advisory boards, research consortiums, and industry academic partnerships to advance the field.
• Lead a high impact publication strategy, ensuring timely and rigorous dissemination of research findings in top tier peer reviewed journals.
• Represent Sanofi as a scientific thought leader at national and international research conferences and symposia.
• Shape the external scientific narrative for Type 2 Immunology through white papers, review articles, and engagement with the broader research community.
• Lead, mentor, and develop a high performing team of research scientists, with an ingrained drug hunting culture.
• Foster a culture of scientific excellence, intellectual curiosity, collaboration, and accountability.
• Set clear research objectives, provide ongoing scientific guidance, and support career development and succession planning.

About you

Basic Qualifications: PhD in immunology, molecular biology, or a closely related field with a minimum of 12 years of experience in the pharmaceutical or biopharmaceutical research industry, with a strong focus on immunology research. Deep expertise in inflammatory biology (ideally Type 2), disease mechanisms, and the evolving therapeutic landscape. Proven experience in translational research with evidence of going from benchside to bedside and back again. Evidence of big data competency by leveraging large data tools to build scientific hypotheses. Demonstrated ability to lead and influence cross functional R&D teams in a matrixed organization. Demonstrated track record of leading successful drug discovery and, or development programs from early research through clinical translation. Strong executive presence with excellent scientific communication, presentation, and stakeholder engagement skills. Strong publication record in high impact, peer reviewed scientific journals.

Preferred Qualifications

• Direct research experience in across multiple inflammatory diseases including but not limited to Type 2 inflammatory diseases.
• In depth knowledge of biologics development and immunotherapy, including antibody engineering and mechanism based drug design.
• Familiarity with regulatory science, including IND or CTA submissions and interactions with health authorities.
• Established network within the academic and scientific community in immunology or related fields.
• Experience building and managing academic industry research partnerships and collaborative research agreements.
• Prior experience managing and developing senior scientific talent.

Why Choose Us?

Bring the miracles of science to life alongside a supportive, future-focused team.

Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs.

Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science.

Help improve the lives of millions of people globally by making drug development quicker and more effective.

Sanofi US endeavours to make our career center accessible to any and all users.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce.

All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

The salary range for this position is: $206,250.00 - $297,916.66 All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.

We are an R&D driven, AI-powered biopharma company committed to improving people’s lives and creating compelling growth. Our team is guided by one purpose: we chase the miracles of science to improve people’s lives. We want to build a healthier, more resilient world, and turn the impossible into the possible by discovering, developing, and delivering medicines and vaccines for millions of people around the world. Discover more about us visiting www.sanofi.com or via our movie We are Sanofi Start a career that makes a difference. Reinvention is in our DNA. It’s what drove our evolution from a small French enterprise to one of the world’s leading biopharma companies. Whether it’s using AI to shorten drug-discovery times or building trust in healthcare, you could be helping our teams make life better for patients, partners, and communities. This is where you grow your career. We open the door for you to explore new opportunities, push your limits, and connect with people who are driven by a shared purpose: we chase the miracles of science to improve people’s lives.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.