Senior Director, Statistical Innovation & Strategy

amgen; United States; Hybrid; USD 224,000 - 303,000; Full time

Job summary

Amgen is seeking a Sr Director, Statistical Innovation in the United States to lead advanced statistical strategy for therapeutic areas. You will shape study designs, estimands, and innovative analysis approaches across late-stage programs, partnering with senior stakeholders worldwide.

You will guide modeling and simulation efforts, ensure regulatory alignment, and mentor biostatistics teams to deliver robust evidence for regulatory submissions and payer decisions.

Qualifications

• PhD or MS with substantial biostatistics experience in drug development.
• Experience leading statistical strategy across complex programs and regulatory filings.
• Proven leadership and cross-functional collaboration in biostatistics.

Responsibilities

• Provide senior advisory input in study design and product strategy.
• Advise on design options, estimands, estimators for objectives.
• Lead modeling and simulation, review design options for regulatory filings.
• Build partnerships to embed innovative design approaches across programs.

Skills

Statistical leadership

Clinical trial design

Modeling & simulation

Regulatory submissions

Education

Doctorate in Statistics/Biostatistics

Master’s degree in Statistics/Biostatistics

Bachelor’s degree + extensive stat content

Job description

Amgen is seeking a Sr Director, Statistical Innovation in the United States to lead advanced statistical strategy for therapeutic areas. You will shape study designs, estimands, and innovative analysis approaches across late-stage programs, partnering with senior stakeholders worldwide.

You will guide modeling and simulation efforts, ensure regulatory alignment, and mentor biostatistics teams to deliver robust evidence for regulatory submissions and payer decisions.