Senior Director, R&D Strategy Execution & Transformation

BeOne Medicines USA, Inc.; United States; Remote; USD 223,000 - 293,000; Full time

Job summary

BeOne Medicines Ltd. seeks a hands-on leader to drive strategic initiatives across its global R&D organization, translating priorities into tangible outcomes and strengthening program management across functions.

Reporting to the VP of R&D Strategy & Operations, you will design governance, executive communications, and operating cadences to enable rapid, evidence-based decision making. The role requires a PhD or advanced degree with substantial experience in biopharma, transformation, and

Qualifications

• Experience in biopharma, life sciences consulting, corporate strategy, transformation, or R&D operations.
• Strong understanding of pharma/biotech industry and R&D value chain; oncology experience is a plus.
• Proven ability to translate ambiguous objectives into structured workplans and drive execution.
• Analytical, problem-solving, organizational, and project management skills.
• Excellent executive communication and story-lining, including senior leadership materials.
• High emotional intelligence and ability to navigate global, matrixed organizations.
• Entrepreneurial, proactive, hands-on, adaptable; comfortable in a fast-paced environment.

Responsibilities

• Lead high-priority R&D transformation initiatives from strategy through implementation.
• Establish PMOs, including milestones, governance, risk, and performance tracking.
• Drive cross-functional alignment and resolve issues; translate priorities into plans.

Skills

Executive communication

Strategic program management

Cross-functional leadership

Problem solving

Change management

Education

Bachelor's degree

PhD

Master's degree

Job description

BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer.

General Description

BeOne Medicines is seeking a highly capable, hands-on leader to drive strategic initiatives and transformation across its global Research & Development organization. Reporting to the VP of R&D Strategy & Operations, this individual will translate R&D strategic priorities into tangible outcomes, lead complex cross-functional initiatives, establish effective program management structures, and strengthen organizational execution. The ideal candidate combines strategic problem-solving with exceptional operational discipline, strong business judgment, and the ability to influence stakeholders across a global, matrixed organization. This is a highly visible role with the opportunity to shape how BeOne executes its R&D strategy and accelerates the development of innovative medicines.

Essential Functions of the Job

• Strategic Initiative Execution & Transformation Lead high-priority R&D transformation initiatives from strategy through implementation, ensuring measurable outcomes. Establish and lead strategic program management offices (PMOs), including workstream design, milestones, governance, risk management, and performance tracking. Drive cross-functional alignment and accountability across Research, Development, and enabling functions; proactively resolve issues and elevate critical decisions. Identify opportunities to improve R&D operating models, processes, organizational effectiveness, and productivity; design and implement sustainable solutions.
• Governance & Operational Excellence Support the design and continuous improvement of R&D governance, strategic planning, goal-setting, and performance management processes. Establish practical management systems and operating cadences that strengthen decision-making, transparency, and follow-through. Partner with functional leaders to translate R&D-wide priorities into actionable plans, clear ownership, and measurable outcomes.
• Executive Engagement & Strategic Support Partner with R&D leadership to address complex strategic and operational challenges. Develop compelling executive communications, decision materials, and progress updates that translate complex information into actionable insights. Support leadership forums, strategic reviews, and high-priority activities of the R&D head office. Contribute to strategic problem-solving and new initiatives as organizational priorities evolve.

Qualifications & Experience

• Experience in biopharma, life sciences consulting, corporate strategy, transformation, R&D operations, or related fields; consulting and industry experience are equally valued.
• Strong understanding of the pharmaceutical/biotechnology industry and R&D value chain; direct drug development or oncology experience is a plus.
• Demonstrated success independently leading complex cross-functional initiatives, transformations, PMOs, or organizational change programs through implementation.
• Exceptional ability to translate ambiguous objectives into structured workplans and drive execution through stakeholders without direct authority.
• Strong analytical, problem-solving, organizational, and project management skills, with excellent attention to detail and follow-through.
• Excellent executive communication and story-lining capabilities, including the ability to independently develop senior leadership materials.
• High emotional intelligence, sound judgment, and the ability to navigate complex global and matrixed organizations.
• Entrepreneurial, proactive, hands-on, and adaptable; comfortable operating in a fast-paced environment with evolving priorities.
• Bachelor's degree required; advanced degree preferred.

What Success Looks Like

Critical R&D initiatives advance with clear ownership, disciplined execution, and measurable results. R&D leadership has greater visibility into priorities, progress, risks, and decisions. Cross-functional teams are better aligned, and strategic decisions translate into sustained organizational change.

Education Required

PhD with 6 years of experience or a master’s degree with 8 years of experience preferred. Exceptions might be made for candidates with relevant experience.

Global Competencies

When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world.

• Fosters Teamwork
• Provides and Solicits Honest and Actionable Feedback
• Self-Awareness
• Acts Inclusively
• Demonstrates Initiative
• Entrepreneurial Mindset
• Continuous Learning
• Embraces Change
• Results-Oriented Analytical Thinking/Data Analysis
• Financial Excellence
• Communicates with Clarity

Salary Range

Salary Range: $223,400.00 - $293,400.00 annually BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan.

Benefits

The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness.

Company Overview

BeOne is a global oncology company that is discovering and developing innovative treatments that are more affordable and accessible to cancer patients worldwide. With a broad portfolio, we are expediting development of our diverse pipeline of novel therapeutics through our internal capabilities and collaborations. We are committed to radically improving access to medicines for far more patients who need them. Our growing global team of more than 11,000 colleagues spans six continents.

Equal Opportunity

BeOne is proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need.

Accommodation

In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact [e-mail].

To learn more about BeOne, please visit www.beonemedicines.com and follow us on LinkedIn, X (formerly known as Twitter), Facebook and Instagram.

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At BeOne, how we work is just as important as the work we do.

Below are our Values that determine the decisions we make and how we do things.

Patients First Driving Excellence Bold Ingenuity Collaborative Spirit