Senior Director, Medicinal Chemistry

USA - 3316 Takeda Development Center Americas, Inc.; Cambridge (MA); Híbrido; USD 212.000 - 333.000; Jornada completa

Descripción de la vacante

Takeda Pharmaceutical Co. is seeking an experienced Senior Director of Medicinal Chemistry in Boston, MA, with hybrid work options. You will lead the department, shape chemistry strategy, and oversee CRO-driven programs to deliver high-quality candidates.

You will mentor a team of chemists, collaborate across biology, pharmacology, and clinical development, and drive innovation using cutting-edge methods while aligning with company priorities.

Formación

• PhD in Chemistry or Medicinal Chemistry or related discipline with extensive experience.
• Proven track record leading drug discovery programs that produced clinical candidates.
• Experience overseeing external CROs and cross-functional collaboration.

Responsabilidades

• Provide strategic leadership and oversight of medicinal chemistry aligned with company priorities.
• Oversee CRO-based medicinal chemistry projects, managing budget, data integrity and IP.
• Mentor internal chemists and develop a high-performing team.
• Partner with biology, pharmacology, and clinical teams to advance candidates.
• Drive innovation through new technologies and best practices.
• Build external partnerships with academia, industry collaborators, and CROs.
• Identify external opportunities to meet strategic scientific and commercial needs.

Conocimientos

Leadership

Medicinal chemistry

CRO management

Project management

Communication

Educación

PhD in Chemistry or Medicinal Chemistry

MS with 21+ years experience

BS with 23+ years experience

Descripción del empleo

Job Description About the role

We are seeking an experienced leader to join the Global Chemistry Leadership Team as Senior Director of Medicinal Chemistry. In this role, the successful candidate will provide strategic guidance and oversight for our medicinal chemistry efforts. Drawing on deep drug-hunting expertise, they will help shape chemistry strategy and portfolio decisions, and ensure alignment with company priorities. They will also oversee medicinal chemistry projects conducted at contract research organizations (CROs), with accountability for their execution and progression.

How you will contribute

Leadership and Strategy

Provide strategic leadership and oversight to the medicinal chemistry department, aligned with company strategy and priorities.

Project Management

Oversee the design, execution, and management of medicinal chemistry projects conducted at CROs, ensuring timely progress and high-quality outcomes, including vendor performance, budget, data integrity, and IP protection.

Team Development

Mentor and develop a team of internal chemists, fostering a collaborative and innovative work environment.

Collaboration

Partner closely with cross-functional teams, including biology, pharmacology, and clinical development, to advance drug candidates from discovery through development.

Innovation

Drive innovation in medicinal chemistry through the integration of new technologies, methodologies, and best practices.

External Partnerships

Build and maintain relationships with external partners, including academic institutions, industry collaborators, and CROs.

Business Development

Identify and create external opportunities that meet the strategic scientific, therapeutic, and commercial needs of the organization.

Qualifications

• Expected education and experience: PhD degree in Chemistry, Medicinal Chemistry, or a related discipline, with 15+ years experience, or MS with 21+ years experience, or BS with 23+ years experience
• Proven track record of leading drug discovery programs that have delivered clinical candidates.

Leadership Skills

Experience leading and developing high-performing teams.

Technical Expertise

Deep understanding of medicinal chemistry principles, project execution, and drug design.

Communication

Excellent verbal and written communication skills, with the ability to explain complex scientific concepts to a broad audience.

CRO Management

Experience managing external CRO partners for medicinal chemistry programs, including vendor oversight, budget and resource management, and data quality, ideally across multiple regions and time zones.

Problem-Solving

Strong analytical and problem-solving skills, with a proactive and innovative approach to challenges.

Adaptability

Ability to adapt to changing priorities and make sound decisions with incomplete or evolving data.

This position is currently classified as “hybrid” in accordance with Takeda’s Hybrid and Remote Work policy.

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location: Boston, MA U.S.

Base Salary Range: $212,000.00 - $333,190.00 The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

For information about our benefits, please click here.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations Boston, MA Worker Type Employee Worker Sub-Type Regular Time Type Full time Job Exempt Yes It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Takeda is an industry-leading, global pharmaceutical company with an unwavering dedication to putting patients at the center of everything we do. We live our values of Takeda-ism – Integrity, Fairness, Honesty, and Perseverance – and are united by our mission to strive towards Better Health and a Brighter Future for people worldwide through leading innovation in medicine. Here, everyone matters and you will be a vital contributor to our inspiring, bold mission. At Takeda, you will make an impact on people’s lives – including your own. Takeda is an equal opportunity employer.

For applicants of U.S and Puerto Rico positions: Click here to learn about our commitment to Equal Employment Opportunity (EEO). If you are limited in the ability to use our job application tool, or otherwise require a reasonable accommodation for a disability please click here.